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haoai@office365.ndmctsgh.edu.tw

專長學科

神經科學 (neuroscience)
蛋白質體學 (proteomics)
質譜儀 (mass spectrometer)在生物醫學上之應用
細胞骨架與小包運輸

研究論文

[01]. Liaw WJ, Tsao CM, Huang GS, Wu CC, Ho ST, Wang JJ, Tao YX, Shui HA* (責任作者). Phosphoproteomics and bioinformatics analyses of spinal cord proteins in rats with morphine tolerance. PLoS One. 2014; 9(1):e83817.

[02]. Huang CY, Chang WS, Shui HA, Hsieh YH, Loh CH, Wang HC, Ji HX, Hsiao CL, Hsu CM, Tsai CW, Bau DT. Evaluation of the contribution of methylenetetrahydrofolate reductase genotypes to Taiwan breast cancer. Anticancer Res. 2014; 34(8):4109-15.

[03]. Ma HI, Hueng DY, Shui HA, Han JM, Wang CH, Lai YH, Cheng SY, Xiao X, Chen MT, Yang YP. Intratumoral decorin gene delivery by AAV vector inhibits brain glioblastomas and prolongs survival of animals by inducing cell differentiation. Int J Mol Sci. 2014;15(3):4393-414.

[04]. Ka SM, Tsai PY, Chao TK, Yang SM, Hung YJ, Chen JS, Shui HA, Chen A. Urine annexin A1 as an index for glomerular injury in patients. Dis Markers. 2014;2014:854163.

[05]. Liaw WJ, Tsao CM, Huang GS, Wu CC, Ho ST, Wang JJ, Tao YX, Shui HA. Phosphoproteomics and bioinformatics analyses of spinal cord proteins in rats with morphine tolerance. PLoS One. 2014;9(1):e83817.

[06]. Tsai CW, Ho CY, Shih LC, Ying TH, Hsieh YH, Chen YC, Chang WS, Huang CY, Pan SB, Shui HA, Chen CP, Wang PS, Bau DT. The joint effect of hOGG1 genotype and smoking habit on endometriosis in Taiwan. Chin J Physiol. 2013; 56(5):263-8.

[07]. Chan CC, Sun GH, Shui HA, Wu GJ. Differential spermatozoal protein expression profiles in men with varicocele compared to control subjects: upregulation of heat shock proteins 70 and 90 in varicocele. Urology. 2013; 81(6):1379.e1-8.

[08]. Yeh CB, Shui HA, Chu TH, Chen YA, Tsung HC, Shyu JF. Hyperpolarisation-activated cyclic nucleotide channel 4 (HCN4) involvement in Tourette's syndrome autoimmunity. J Neuroimmunol. 2012; 250(1-2):18-26.

[09]. Tsai YF, Shih CH, Su YT, Yao CH, Lian JF, Liao CC, Hsia CW, Shui HA, Rani R. The total synthesis of a ganglioside Hp-s1 analogue possessing neuritogenic activity by chemoselective activation glycosylation. Org Biomol Chem. 2012; 10(5):931-4.

[10]. Chiang SY, Tsai ML, Wang CY, Chen A, Chou YC, Hsia CW, Wu YF, Chen HM, Huang TH, Chen PH, Liu HT, Shui HA. Proteomic analysis and identification of aqueous humor proteins with a pathophysiological role in diabetic retinopathy. J Proteomics. 2012; 75(10):2950-9.

[11]. Chen PH, Wang CY, Hsia CW, Ho MY, Chen A, Tseng MJ, Wu YF, Chen HM, Huang TH, Liu HT, Shui HA* (責任作者), Impact of taxol on dermal papilla cells - A proteomics and bioinformatics analysis. J Proteomics. 2011;74:2760-2773.

[12]. Chiang SY, Tsai ML, Wang CY, Chen A, Chou YC, Hsia CW, Wu YF, Chen HM, Huang TH, Chen PH, Liu HT, Shui HA*(責任作者). Proteomic analysis and identification of aqueous humor proteins with a pathophysiological role in diabetic retinopathy Journal of Proteomics. J Proteomics. 2012 Jun 6;75(10):2950-9.

[13]. Huang TH, Ka SM, Hsu YJ, Shui HA* (共同責任作者), Tang BL, Hu KY, Chang JL, Chen A. Rab23 plays a role in the pathophysiology of mesangial cells--a proteomic analysis. Proteomics. 2011;11:380-94.

[14]. Chu CC, Wang JJ, Chen KT, Shieh JP, Wang LK, Shui HA*(共同責任作者), Ho ST. Neurotrophic effects of tianeptine on hippocampal neurons: a proteomic approach. J Proteome Res. 2010;9:936-44.

[15]. Huang TH, Shui HA*(共同責任作者), Ka SM, Tang BL, Chao TK, Chen JS, Lin YF, Chen A. Rab 23 is expressed in the glomerulus and plays a role in the development of focal segmental glomerulosclerosis. Nephrol Dial Transplant. 2009;24:743-54.

[16]. Chan CC, Shui HA*(共同責任作者), Wu CH, Wang CY, Sun GH, Chen HM, Wu GJ. Motility and protein phosphorylation in healthy and asthenozoospermic sperm. J Proteome Res. 2009;8:5382-6.

[17]. Shui HA (第一作者), Hsia CW, Chen HM, Chang TC, Wang CY. Proteomics and bioinformatics analysis of lovastatin-induced differentiation in ARO cells. J Proteomics. 2012;75:1170-1180.

[18]. Lin CY, Wang V, Shui HA (並列第一作者), Juang RH, Hour AL, Chen PS, Huang HM, Wu SY, Lee JC, Tsai TL, Chen HM. A comprehensive evaluation of imidazole-zinc reverse stain for current proteomic researches. Proteomics. 2009;9:696-709.

[19]. Hsia CW, Shui HA, Wang CY, Yu HM, Ho MY, Cheng KT, Tseng MJ. Proteomics demonstration that histone H4 is a colchicine-induced retro-modulator of growth and alkaline phosphatase activity in hair follicle dermal papilla culture. J Proteomics. 2011;74:805-16.

[20]. Wang CY, Shui HA, Chang TC. In vivo evidence of duality effects for lovastatin in a nude mouse cancer model. Int J Cancer. 2010;126:578-82.

[21]. Tsai PY, Ka SM, Chang JM, Chen HC, Shui HA, Li CY, et al. Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation. Free Radic Biol Med. 2011;51:744-54.

[22]. Wu HC, Chen TN, Kao SH, Shui HA, Chen WJ, Lin HJ, Chen HM. Isoelectric focusing management: an investigation for salt interference and an algorithm for optimization. J Proteome Res. 2010;9:5542-56.

[23]. Hwang JC, Chang LC, Lin YF, Shui HA, Chen JS. Effects of fungal statins on high-glucose-induced mouse mesangial cell hypocontractility may involve filamentous actin, t-complex polypeptide 1 subunit beta, and glucose regulated protein 78. Transl Res. 2010;156:80-90.

[24]. Chu CC, Shieh JP, Shui HA, Chen JY, Hsing CH, Tzeng JI, Wang JJ, Ho ST. Tianeptine reduces morphine antinociceptive tolerance and physical dependence. Behav Pharmacol. 2010;21:523-9.

[25]. Chin LT, Huang PR, Hu KY, Huang NK, Chiu CD, Hour AL, Shui HA, Chen HM. A proteomics-based translational approach reveals an antifolate resistance inherent in human plasma derived from blood donation. J Proteome Res. 2010;9:3091-102.

[26]. Wen ZH, Wu GJ, Hsu LC, Chen WF, Chen JY, Shui HA, Chou AK, Wong CS. N-Methyl-D-aspartate receptor antagonist MK-801 attenuates morphine tolerance and associated glial fibrillary acid protein up-regulation: a proteomic approach. Acta Anaesthesiol Scand. 2008;52:499-508.

[27]. Shui, H.A. (第一作者), T.H. Huang, S.M. Ka, P.H. Chen, Y.F. Lin, and A. Chen, Urinary proteome and potential biomarkers associated with serial pathogenesis steps of focal segmental glomerulosclerosis. Nephrol Dial Transplant, 2008. 23(1): p. 176-85.

[28]. Shui, H.A. (第一作者), S.M. Ka, S.M. Yang, Y.F. Lin, Y.F. Lo, and A. Chen, Osteopontin as an injury marker expressing in epithelial hyperplasia lesions helpful in prognosis of focal segmental glomerulosclerosis. Transl Res, 2007. 150(4): p. 216-22.

[29]. Shui, H.A. (第一作者), S.M. Ka, W.M. Wu, Y.F. Lin, Y.C. Hou, L.C. Su, and A. Chen, LPS-evoked IL-18 expression in mesangial cells plays a role in accelerating lupus nephritis. Rheumatology (Oxford), 2007. 46(8): p. 1277-84.

[30]. Shui, H.A. (第一作者), S.T. Ho, J.J. Wang, C.C. Wu, C.H. Lin, Y.X. Tao, and W.J. Liaw, Proteomic analysis of spinal protein expression in rats exposed to repeated intrathecal morphine injection. Proteomics, 2007. 7(5): p. 796-803.

[31]. Cheng, C.W., S.M. Ka, S.M. Yang, H.A. Shui, Y.W. Hung, P.C. Ho, Y.C. Su, and A. Chen, Nephronectin expression in nephrotoxic acute tubular necrosis.Nephrol Dial Transplant, 2008. 23(1): p. 101-9.

[32]. Ka, S.M., X.R. Huang, H.Y. Lan, P.Y. Tsai, S.M. Yang, H.A. Shui, and A. Chen, Smad7 gene therapy ameliorates an autoimmune crescentic glomerulonephritis in mice. J Am Soc Nephrol, 2007. 18(6): p. 1777-88.

[33]. Ka, S.M., C.W. Cheng, H.A. Shui, W.M. Wu, D.M. Chang, Y.C. Lin, and A. Chen, Mesangial cells of lupus-prone mice are sensitive to chemokine production.Arthritis Res Ther, 2007. 9(4): p. R67.