Experience

Jul. 2020 – , Director & Chairman, Dept. of Pharmacology, National Defense Medical Center, Taipei, Taiwan, R. O. C.
Aug. 2016 – , Professor, Dept. of Pharmacology, National Defense Medical Center, Taipei, Taiwan, R. O. C.
Aug. 2005 – Jul. 2016, Associate Professor, Dept. of Pharmacology, National Defense Medical Center, Taipei, Taiwan, R. O. C.
Feb. 2001 – Jul. 2005, Assistant Professor, Dept. of Pharmacology, National Defense Medical Center, Taipei, Taiwan, R. O. C.
May 2000 – Jul. 2000, Visiting Research Fellow, Dept. of Biochemistry, University of Southampton, Southampton, U. K. (funded by the Royal Society, U. K.)
Aug. 1999 – Jan. 2001, Assistant Professor, Graduate Institute of Clinical Medical Sciences, Chang Gung University, Tao-Yuan, Taiwan, R. O. C.
Nov. 1998 – Jan. 2001, Research Fellow, Dept. of Anesthesiology, Chang Gung Memorial Hospital, Tao-Yuan, Taiwan, R. O. C.
Feb. 1998 – Oct. 1998, Postdoctoral Research Fellow, Dept. of Pharmacology, Chang Gung University, Tao-Yuan, Taiwan, R. O. C.
Nov. 1997 – Jan. 1998, Postdoctoral Research Fellow, Dept. of Pharmacology, National Defense Medical Center, Taipei, Taiwan, R. O. C.
Jun. 1993 – Jul. 1994, Research Assistant, Lab. of Endocrinology, Institute of Zoology, Academia Sinica, Taipei, Taiwan, R. O. C.

Publication

Lok-Hi Chow, Yuan-Hao Chen, Ying-Jie Chen, Hao-Yuan Hung, and Eagle Yi-Kung Huang (2022) Intrathecal injections of non-peptide oxytocin receptor agonists, WAY 267,464 and TC OT 39, induce significant anti-hyperalgesia in both male and female rats that underwent intraplantar carrageenan injection. Peer J. (submitted)


Kuan-Yin Tseng, Tung-Tai Kuo, Vicki Wang, Eagle Yi-Kung Huang, Kuo-Hsing Ma, Lars Olson, Barry J Hoffer, and Yuan-Hao Chen (2022) Tetrabenazine mitigates aberrant release and clearance of dopamine in the nigrostriatal system, and alleviates L-DOPA-induced dyskinesia in a mouse model of Parkinson's disease. Journal of Parkinson's Disease (in press)

Lok-Hi Chow, Hao-Yuan Hung, Wan-Chuan Wu, Yuan-Hao Chen, Weihong Pan, and Eagle Yi-Kung Huang. (2022) Estrogen can abolish oxytocin-induced spinal antihyperalgesia. Psychoneuroendocrinology 136: 105603.

Hao-Yuan Hung, Wu-Chien Chien, Chi-Hsiang Chung, Li-Ting Kao, Lok-Hi Chow, Yuan-Hao Chen, Jolanta H. Kotlińska, Jerzy Silberring, and Eagle Yi-Kung Huang. (2021) Patients with alcohol use disorder increase pain and analgesics use: A nationwide population-based cohort study. Drug and Alcohol Dependence 229(Pt A): 109102.

Hsiao-Ming Chao, Eagle Yi-Kung Huang, and Chieh-Fu Chen. (2021) The essentials for the study of vision improving drugs. Journal of Chinese Medicine Research Vol.33: 1-18.

Mielczarek P, Hartman K, Drabik A, Hung HY, Huang EY, Gibula-Tarlowska E, Kotlinska JH, Silberring J. (2021) Hemorphins-From Discovery to Functions and Pharmacology. Molecules 26(13): 3879.

Wang V, Kuo TT, Huang EY, Ma KH, Chou YC, Fu ZY, Lai LW, Jung J, Choi HI, Choi DS, Li Y, Olson L, Greig NH, Hoffer BJ, and Chen YH. (2021) Sustained Release GLP-1 Agonist PT320 Delays Disease Progression in a Mouse Model of Parkinson's Disease. ACS Pharmacol Transl Sci. 4(2): 858-869.

Hung HY, Chow LH, Kotlinska JH, Drabik A, Silberring J, Chen YH, and Huang EY. (2021) LVV-hemorphin-7 (LVV-H7) plays a role in antinociception in a rat model of alcohol-induced pain disorders. Peptides 136:170455.

Loh SH, Chang CY, Huang SF, Chao SC, Lin WK, Huang EY, Tsai CS, and Tsai YT. (2020) Functional effects of urotensin-II on intracellular pH regulators in human radial artery smooth muscle cells. Peptides 126: 170236

Chen YH, Wang V, Huang EY, Chou YC, Kuo TT, Olson L, and Hoffer BJ. (2019) Delayed Dopamine Dysfunction and Motor Deficits in Female Parkinson Model Mice. Int J Mol Sci. 20(24) pii: E6251

Chen YH, Hsieh TH, Kuo TT, Kao JH, Ma KH, Huang EY, Chou YC, Olson L, and Hoffer BJ. (2019) Release parameters during progressive degeneration of dopamine neurons in a mouse model reveal earlier impairment of spontaneous than forced behaviors. J Neurochem. 150(1): 56-73

Wu WL, Cheng SJ, Lin SH, Chuang YC, Huang EY, and Chen CC. (2019) The Effect of ASIC3 Knockout on Corticostriatal Circuit and Mouse Self-grooming Behavior. Front Cell Neurosci. 13: 86

Chen YH, Lin BJ, Hsieh TH, Kuo TT, Miller J, Chou YC, Huang EY, and Hoffer BJ. (2019) Differences in nicotine encoding dopamine release between the striatum and shell portion of the nucleus accumbens. Cell Transplantation 28(3): 248-261

Yuan-Hao C, Kuo TT, Huang EY, Hoffer BJ, Kao JH, Chou YC, Chiang YH, and Miller J. (2018) Nicotine-induced conditional place preference is affected by head injury: correlation with dopamine release in the nucleus accumbens shell. Int. J. Neuropsychopharmacol. 21(10): 949-961

Chen YH, Kuo TT, Kao JH, Huang EY, Hsieh TH, Chou YC, and Hoffer BJ. (2018) Exercise ameliorates motor deficits and improves dopaminergic functions in the rat hemi-Parkinson's model. Sci Rep. 8(1): 3973

Chow LH, Chen YH, Lai CF, MD, Lin TY, Chen YJ, Kao JH, and Huang EY. (2018) Sex difference of angiotensin IV-, LVV-hemorphin 7-, and oxytocin-induced antiallodynia at the spinal level in mice with neuropathic pain. Anesthesia & Analgesia 126(6): 2093-2101

Chen YH, Kuo TT, Huang EY, Chou YC, Chiang YH, Hoffer BJ, and Miller J (2018) Effect of traumatic brain injury on nicotine-induced modulation of dopamine release in the striatum and nucleus accumbens shell. Oncotarget 9: 10016-10028

Chen YH, Huang EY, Kuo TT, Hoffer BJ, Miller J, Chou YC, and Chiang YH. (2017) Dopamine release in the nucleus accumbens is altered following traumatic brain injury. Neuroscience 348: 180-190

Chen YH, Huang EY, Kuo TT, Miller J, Chiang YH, and Hoffer BJ. (2017) Impact of traumatic brain injury on dopaminergic transmission. Cell Transplantation 26(7): 1156-1168

Lok-Hi Chow, Yuan-Hao Chen, Wan-Chuan Wu, En-Pei Chang, and Eagle Yi-Kung Huang (2016) Sex difference in oxytocin-induced anti-hyperalgesia at the spinal level in rats with intraplantar carrageenan-induced inflammation. PLoS ONE 11(9): e0162218

Eagle Yi-Kung Huang, Yuan-Hao Chen, Tzu-Ying Huang, Ying-Jie Chen, and Lok-Hi Chow (2016) Chronic administration of nandrolone increases susceptibility to morphine dependence without correlation with LVV-hemorphin 7 in rats. Neuropeptides 59: 63-69

Yuan-Hao Chen, Eagle Yi-Kung Huang, Tung-Tai Kuo, Barry J. Hoffer, Pei-Jie Wu, Hsin-I Ma, Jing-Jr Tsai, Yu-Ching Chou, and Yung-Hsiao Chiang (2016) Levetiracetam prophylaxis ameliorates seizure epileptogenesis after fluid percussion injury. Brain Res. 1642: 581-589

Eagle Yi-Kung Huang, Yuh-Chiang Shen, and Chieh-Fu Chen (2016) Mitochondria: Target for the develop of anti-inflammatory drugs. Journal of Chinese Medicine 27(1): 2701004

Lok-Hi Chow, Pao-Luh Tao, Yuan-Hao Chen, Yu-Hui Lin and Eagle Yi-Kung Huang (2015) Angiotensin IV possibly acts through PKMzeta in hippocampus to regulate cognitive memory in rats. Neuropeptides 53: 1-10

Pao-Pao Yang, Geng-Chang Yeh, Eagle Yi-Kung Huang, Ping-Yee Law, Horace H. Loh and Pao-Luh Tao (2015) Effects of dextromethorphan and oxycodone on treatment of neuropathic pain in mice. J. Biomed. Sci. 22(1): 81

Yuan-Hao Chen, Eagle Yi-Kung Huang, Tung-Tai Kuo, Hsin-I Ma, Barry J. Hoffer, Pi-Fen Tsui, Jing-Jr Tsai, Yu-Ching Chou and Yung-Hsiao Chiang (2015) Dopamine release impairment in striatum after different levels of cerebral cortical fluid percussion injury. Cell Transplantation 24(10): 2113-2128

Yi-Ting Tsai, Chung-Yi Lee, Chih-Chin Hsu, Chung-Yi Chang, Ming-Kai Hsueh, Eagle Yi-Kung Huang, Chien-Sung Tsai, and Shih-Hurng Loh (2014) Effects of Urotensin II on intracellular pH regulation in cultured human internal mammary artery smooth muscle cells. Peptides 56: 173-182

Eagle Yi-Kung Huang, Tung-Tai Kuo, Jing-Jr Tsai, Pi-Fen Tsui, Yu-Ching Chou, Tsai Tung-Han, Hsin-I. Ma, Yung-Hsiao Chiang and Yuan-Hao Chen (2014) Remote effects on the striatal dopamine system after fluid percussion injury. Behavioural Brain Research 267: 156-172

陳介甫、黃翊恭、吳令怡、廖志飛 (2014) 發炎、發炎體、抗發炎藥 (ISBN 978-986-7825-95-7) 知音出版社

Eagle Yi-Kung Huang, Pi-Fen Tsui, Tung-Tai Kuo, Jing-Jr Tsai, Yu-Ching Chou, Hsin-I Ma, Yung-Hsiao Chiang and Yuan-Hao Chen (2014) Amantadine ameliorates dopamine-releasing deficits and behavioral deficits in rats after fluid percussion injury. PLoS ONE 9(1): e86354

Ling-Yi Wu, Chieh-Fu Chen and Eagle Yi-Kung Huang (2013) Obesity related metabolic complications and anti-obesity drugs. Journal of Chinese Medicine 24(2): 261-277

Yuan-Hao Chen, Tong-Tai Kuo, Ming-Ting Chu, Hsin-I Ma, Yung-Hsiao Chiang and Eagle Yi-Kung Huang (2013) Postnatal systemic inflammation exacerbates impairment of hippocampal synaptic plasticity in animal seizure model. Neuroimmunomodulation 20(4): 223-232

Weihong Pan, Xiaojun Wu, Yi He, Hung Hsuchou, Eagle Yi-Kung Huang, Pramod K. Mishra and Abba J. Kastin (2013) Brain interleukin-15 in neuroinflammation and behavior. Neurosci. Biobehav. Rev. 37(2): 184-192

Lok-Hi Chow, Pao-Luh Tao, Jin-Chung Chen, Ruey-Ming Liao, En-Pei Chang and Eagle Yi-Kung Huang (2013) A possible correlation between oxytocin-induced and angiotensin IV-induced anti-hyperalgesia at the spinal level in rats. Peptides 39(1): 21-28

Pao-Pao Yang, Eagle Yi-Kung Huang, Yu-Ying Fu, Tsai-Shan Ho and Pao-Luh Tao (2012) Post-treatment of dextromethorphan on methamphetamine-induced drug-seeking and behavioral sensitization. Synapse 66(10): 858-869

Bor-Chih Cheng, Pao-Luh Tao, Ya-Yun Cheng and Eagle Yi-Kung Huang (2012) LVV-hemorphin 7 and angiotensin IV in correlation with antinociception and anti-thermal hyperalgesia in rats. Peptides 36(1): 9-16

Weihong Pan, Hung Hsuchou, Bhavaani Jayaram, Reas S. Khan, Eagle Yi-Kung Huang, Xiaojun Wu, Chu Chen and Abba J. Kastin (2012) Leptin action on nonneuronal cells in the CNS: potential clinical applications. Ann N Y Acad Sci. 1264(1): 64-71

Shih-Lin Chang, Yao-Chang Chen, Yung-Hsin Yeh, Yu-Jun Lai, Hung-I Yeh, Cheng-I Lin, Yung-Kuo Lin, Yenn-Jiang Lin, Tsu-Juey Wu, Yi-Kung Huang, Shih-Ann Chen and Yi-Jen Chen (2011) Heart failure enhances arrhythmogenesis in pulmonary veins. Clin. Exp. Pharmacol. Physiol. 38(10): 666-674

Jen-Hsin Kao, Eagle Yi-Kung Huang and Pao-Luh Tao (2011) NR2B subunit of NMDA receptor at nucleus accumbens is involved in morphine rewarding effect by siRNA study. Drug Alcohol Depend. 118(2-3): 366-374

Pao-Luh Tao, Jain-Fang Chen and Eagle Yi-Kung Huang (2011) Dextromethorphan attenuated the higher vulnerability to inflammatory thermal hyperalgesia caused by prenatal morphine exposure in rat offspring. J. Biomed. Sci. 18(1): 64

Shiou-Lan Chen, Kuei-Ying Hsu, Eagle Yi-Kung Huang, Ru-Band Lu and Pao-Luh Tao (2011) Low doses of dextromethorphan attenuate morphine-induced rewarding via the sigma-1 receptor at ventral tegmental area in rats. Drug Alcohol Depend. 117(2-3): 164-169

Chun-Hung Wu, Pao-Luh Tao and Eagle Yi-Kung Huang (2010) Distribution of neuropeptide FF (NPFF) receptors in correlation with morphine-induced reward in the rat brain. Peptides 31(7): 1374-1382

Ling-Yi Wu, Eagle Yi-Kung Huang and Pao-Luh Tao (2010) Co-administration of dextromethorphan during pregnancy and throughout lactation prevents morphine-induced hyperprolactinemia in female rats. Fertility and Sterility 93(5): 1686-1694

Ling-Yi Wu, Jain-Fang Chen, Pao-Luh Tao and Eagle Yi-Kung Huang (2009) Attenuation by dextromethorphan on the higher liability to morphine-induced reward, caused by prenatal exposure of morphine in rat offspring. J. Biomed. Sci. 16: 106

Wei-Li Wu, Chih-Hung Wang, Eagle Yi-Kung Huang and Chih-Cheng Chen (2009) ASIC3-/- Female Mice with Hearing Deficit Affects Social Development of Pups. PLoS ONE 4(8): e6508

Chung-Shiun Yang, Jen-Hsin Kao, Eagle Yi-Kung Huang and Pao-Luh Tao (2008) The role of the NR2B subunit of NMDA receptors in morphine rewarding, drug seeking, and behavioral sensitization. Journal of Medical Sciences 28(6): 245-253

Yu-Jun Lai, Eagle Yi-Kung Huang, Hung-I Yeh, Yen-Lin Chen, Jim Jung-Ching Lin and Cheng-I Lin (2008) On the mechanisms of arrhythmias in the myocardium of mXinalpha-deficient murine left atrial-pulmonary veins. Life Sci. 83: 272-283

Wei-Li Wang, Sheau-Farn Yeh, Eagle Yi-Kung Huang, Yu-Ling Lu, Chun-Fa Wang, Chi-Ying F. Huang and Wey-Jinq Lin (2007) Mitochondrial anchoring of PKC by PICK1 confers resistance to etoposide-induced apoptosis. Apoptosis 12: 1857-1871

Wei-Ming Lue, Eagle Yi-Kung Huang, San-Nan Yang, Chih-Shung Wong and Pao-Luh Tao (2007) Post-treatment of dextromethorphan reverses morphine effect on conditioned place preference in rats. Synapse 61(6): 420-428

Eagle Yi-Kung Huang, Hsiang-Jen Hsiao, Wei-Ming Lue and Pao-Luh Tao (2007) U-50,488 decreased the rewarding effect and mesolimbic dopamine neuron activity induced by morphine in rats. Journal of Medical Sciences 27(1): 15-22

Pao-Pao Yang, Eagle Yi-Kung Huang, Geng-Chang Yeh and Pao-Luh Tao (2006) Co-administration of dextromethorphan with methamphetamine attenuates methamphetamine-induced rewarding and behavioral sensitization. J. Biomed. Sci. 13(5): 695-702

Jin-Chung Chen, Wei-Hsin Lee and Eagle Yi-Kung Huang (2006) Rat NPFF1 receptor-mediated signaling: functional comparison of neuropeptide FF (NPFF), FMRFamide and PFR(Tic)amide. Peptides 27(5): 1005-1014

Pao-Luh Tao, Kai-Wen Liang, Wen-Yi Sung, Yung-Tsun Wu and Eagle Yi-Kung Huang (2006) Nalbuphine is effective in decreasing the rewarding effect and drug-seeking behavior induced by morphine in rats. Drug Alcohol Depend. 84: 175-181

Pao-Luh Tao, Yong-Shang Lai, Lok-Hi Chow and Eagle Yi-Kung Huang (2005) Effects of morphine and endomorphins on the polysynaptic reflex in the isolated rat spinal cord. N-S Arch. Pharmacol. 371: 72-80

Shiou-Lan Chen, Eagle Yi-Kung Huang, Lok-Hi Chow and Pao-Luh Tao (2005) Dextromethorphan differentially affects opioid antinociception in rats. Br. J. Pharmacol. 144(3): 400-404

Lok-Hi Chow, Eagle Y.-K. Huang, Shung-Tai Ho, Shen-Kou Tsai and Pao-Luh Tao (2004) Dextromethorphan potentiates morphine-induced antinociception at both spinal and supraspinal sites but not related to descending serotoninergic or adrenergic pathways. J. Biomed. Sci. 11(6): 717-725

Lok-Hi Chow, Eagle Y.-K. Huang, Shung-Tai Ho, Tak-Yu Lee and Pao-Luh Tao (2004) Dextromethorphan potentiates morphine antinociception at the spinal level in rats. Can. J. Anaesth. 51(9): 905-910

Eagle Yi-Kung Huang, Ching-Ming Chen and Pao-Luh Tao (2004) Supraspinal anti-allodynic and rewarding effects of endomorphins in rats. Peptides 25(4): 577-583

Eagle Yi-Kung Huang, Te-Chen Liu and Pao-Luh Tao (2003) Co-administration of dextromethorphan with morphine attenuates morphine rewarding effect and related dopamine release at the nucleus accumbens. N-S Arch. Pharmacol. 368: 386-392

Jin-Chung Chen, Pao-Luh Tao, Jihn-Yih Li, Chung-Hang Wong and Eagle Yi-Kung Huang (2003) Endomorphin-1 and –2 induce naloxone-precipitated withdrawal syndromes in rats. Peptides 24(3): 477-481

Eagle Yi-Kung Huang, Jihn-Yih Li, Chung-Hang Wong, Peter Pei-Chiung Tan and Jin-Chung Chen (2002) Dansyl-PQRamide, a possible neuropeptide FF receptor antagonist, induces conditioned place preference. Peptides 23(3): 489-496

Jin-Chung Chen, Kai-Wen Liang, Yi-Kung Huang, Cheng-Sheng Liang and Yao-Chang Chiang (2001) Significance of glutamate and dopamine neurons in the ventral pallidum in the expression of behavioral sensitization to amphetamine. Life Sci. 68(9): 973-983

Jihn-Yih Li, Chung-Hang Wong, Eagle Y.-K. Huang, Yen-Chien Lin, Yun-Long Chen, Peter P. C. Tan and Jin-Chung Chen (2001) Modulation of spinal serotonin activity affect the development of morphine tolerance. Anesthesia and Analgesia 92(6): 1563-1568

Jin-Chung Chen, Kai-Wen Liang and Eagle Yi-Kung Huang (2001) Differential effects of endomorphin-1 and -2 on amphetamine sensitization: neurochemical and behavioral aspects. Synapse 39(3): 239-248

Eagle Yi-Kung Huang, Jihn-Yih Li, Peter Pei-Chiung Tan, Chung-Hang Wong and Jin-Chung Chen (2000) The cardiovascular effects of PFRFamide and PFR(Tic)amide, a possible agonist and antagonist of neuropeptide FF (NPFF). Peptides 21(2): 205-210

Peter Pei-Chiung Tan, Jin-Chung Chen, Jihn-Yih Li, Kai-Wen Liang, Chung-Hang Wong and Eagle Yi-Kung Huang (1999) Modulation of naloxone-precipitated morphine withdrawal syndromes in rats by neuropeptide FF analogs. Peptides 20(10): 1211-1217

J.-C. Chen, J.-Y. Li, K.-W. Liang and Y.-K. Huang (1999) Neuropeptide FF potentiates the behavioral sensitization to amphetamine and alters the level of neurotransmitters in the median prefrontal cortex. Brain Res. 816(1): 220-224

E. Y.-K. Huang, J. Bagust, R. P. Sharma and R. J. Walker (1998) The effect of FMRFamide-like peptides on electrical activity in isolated mammalian spinal cord. Neuroscience Res. 30: 295-301

S. J. Perry, E. Y.-K. Huang, D. Cronk, J. Bagust, R. Sharma, R. J. Walker, S. Wilson and J. F. Burke (1997) A human gene encoding morphine modulating peptides related to NPFF and FMRFamide. FEBS Letters 409(3): 426-430

Eagle Yi-Kung Huang, Jeff Bagust, Ram P. Sharma and Robert J. Walker (1997) FLFQPQRFamide (NPFF) inhibits the fast wave of the evoked field potential in the rat isolated spinal cord preparation. Br. J. Pharmacol. 120(SS): 233P

Eagle Yi-Kung Huang, Jeff Bagust, Ram P. Sharma and Robert J. Walker (1996) Naloxone and desaminoYFLFQPQRamide block potentiation by FLFQPQRFamide (NPFF) of the rat isolated spinal cord monosynaptic reflex (MSR). Br. J. Pharmacol. 117(SS): 314P

CONFERENCE ABSTRACTS:

Eagle Yi-Kung Huang, Yuan-Hao Chen, and Lok-Hi Chow (2019) Sex difference in oxytocin-induced antihyperalgesia and antiallodynia at the spinal cord. The 5th Meeting of the Japanese Branch of International Neuropeptide Society, 26-27 October 2019.

Hao-Yuan Hung, Yuan-Hao Chen, and Eagle Yi-Kung Huang (2019) The potential role of LVV-hemorphin 7 in alcohol-induced pain disorders. 20th International Congress of the Polish Pharmacological Society. Lublin, Poland, 5-7 June 2019.

Eagle Yi-Kung Huang, Lok-Hi Chow, Yuan-Hao Chen, and Ai-Lun Tsai (2018) Effects of dextromethorphan on nicotine-induced reward, behavioral sensitization, withdrawal signs, and drug seeking-related behavior in rats. The College on Problems of Drug Dependence (CPDD) annual meeting, San Diego, California, U.S.A.

Lok-Hi Chow, Yuan-Hao Chen, Ying-Jie Chen, and Eagle Yi-Kung Huang (2016) Angiotensin IV acts through c-Met to suppress hippocampal long-term depression (LTD) with a possible connection with memory decay in rats. Zing Conferences, Memory Mechanisms in Health and Disease, Tampa, Florida, U.S.A.

Eagle Yi-Kung Huang, Yuan-Hao Chen, Tzu-Ying Huang, Ying-Jie Chen, and Lok-Hi Chow (2016) Chronic administration of nandrolone increases susceptibility to morphine dependence without correlation with LVV-hemorphin 7 in rats. The College on Problems of Drug Dependence (CPDD) annual meeting, Palm Springs, California, U.S.A.

Eagle Yi-Kung Huang (2012) LVV-hemorphin 7, angiotensin IV, and oxytocin in regulation of pain at the spinal cord. Zing Peptide Chemistry Conference, Cancun, Occidental Grand Xcaret Hotel, Mexico

Wan-Chun Wu, Pao-Luh Tao, and Eagle Yi-Kung Huang (2012) Sex difference of oxytocin-induced anti-hyperalgesia at the spinal level in rats with intraplantar carrageenan-induced inflammation. 14th World Congress on Pain, Milan, Italy

Eagle Yi-Kung Huang, En-Pei Chang, Ya-Yun Cheng, and Pao-Luh Tao (2011) Potential use of intrathecal oxytocin and related peptides in the treatment of inflammatory hyperalgesia. New Frontiers in Persistent Pain Conference, Paris, France

Eagle Yi-Kung Huang, En-Pei Chang, and Pao-Luh Tao (2010) A possible correlation between the oxytocin-induced and angiotensin IV-induced anti-hyperalgesia at the spinal level in rats. 5th International Peptide Symposium in conjunction with 47th Japanese Peptide Symposium, Kyoto, Japan

Eagle Yi-Kung Huang and Pao-Luh Tao (2009) A different view in searching for a new drug target: insulin-regulated amino peptidase (IRAP). The 2nd Protein and Peptide Conference & The 2nd World Congress of Industrial Biotechnology 2009, Seoul, Korea

Eagle Yi-Kung Huang, Ya-Yun Cheng, and Pao-Luh Tao (2008) LVV-hemorphin-7 and angiotensin IV in correlation with anti-hyperalgesia in rats. 12th World Congress on Pain, Glasgow, U. K.

Shu-Hsuan Chou, Tsung-Hsun Yang, Eagle Yi-Kung Huang, and Pao-Luh Tao (2007) Mechanisms of dextromethorphan on treatment of morphine rewarding effect. 38th International Narcotics Research Conference, Berlin, Germany

Eagle Yi-Kung Huang, Jun-Hong Wu, and Pao-Luh Tao (2007) Possible mechanisms of neuropeptide FF (NPFF) to modulate the rewarding effect of morphine in rats. 38th International Narcotics Research Conference, Berlin, Germany

Pao-Pao Yang, Sue-Yi Chen, Eagle Yi-Kung Huang, and Pao-Luh Tao (2007) ASIC3 may play an important role in primary afferent depolarization in the spinal cord of rats. 38th International Narcotics Research Conference, Berlin, Germany

Eagle Yi-Kung Huang, Kuei-Ying Hsu, and Pao-Luh Tao (2006) Acid-sensing ion channel 1a (ASIC1a) may play an important role in the expression of morphine addiction. Joint Meeting of the 28th Annual Meeting of the Japanese Society of Biological Psychiatry, the 36th Annual Meeting of the Japanese Society of Neuropsychopharmacology, the 49th Annual Meeting of the Japanese Society of Neurochemistry, Nagoya, Japan

Jain-Fang Chen, Pao-Luh Tao, and Eagle Yi-Kung Huang (2006) Co-administration of dextromethorphan during pregnancy reverses morphine-potentiated psychological dependence and inflammatory hyperalgesia in rat offspring from morphine-addicted dams. 6th European Opioid Conference, Salamanca, Spain

P.-L. Tao, W.-Y. Sung, P.-C. Wu, and E. Y.-K. Huang (2004) Nalbuphine is effective on prevention of morphine addiction. 35th International Narcotics Research Conference, Kyoto, Japan

E. Y.-K. Huang, C.-F. Wu, and P.-L. Tao (2004) Acid-sensing ion channels (ASICs) may play important roles in spinal nociception and hyperalgesia. 35th International Narcotics Research Conference, Kyoto, Japan

P. L. Tao, W. Y. Sung, P. C. Wu, and E. Y.-K. Huang (2003) Dextromethorphan is effective on treatment of morphine addiction. 34th International Narcotics Research Conference, Perpignan, France

E. Y.-K. Huang, Y. H. Lai, and P. L. Tao (2003) The effects of mu-opioids on polysynaptic reflex in the isolated spinal cord preparation of rats. 34th International Narcotics Research Conference, Perpignan, France

E. Y.-K. Huang, J.-C. Chen, and P.-L. Tao (2002) PFR(Tic)amide, a possible antagonist of neuropeptide FF, produces analgesia intrathecally and attenuates amphetamine-induced locomotor sensitization. XIVth World Congress of Pharmacology, San Francisco, CA, U. S. A.

P.-L. Tao, T. C. Liu, and E. Y.-K. Huang (2002) Effect of dextromethorphan on the rewarding and behavioral sensitization induced by morphine. XIVth World Congress of Pharmacology, San Francisco, CA, U. S. A.

P.-L. Tao, C.-M. Chen, and E. Y.-K. Huang (2002) Effects of supraspinal endomorphin-1 and endomorphin–2 on allodynia and rewarding in rats. 33rd International Narcotics Research Conference, Asilomar, Pacific Grove, CA, U. S. A.

E. Y.-K. Huang, H.-J. Hsiao, and P.-L. Tao (2002) The effects of U-50488, a kappa opioid agonist, on morphine rewarding and dependence. 33rd International Narcotics Research Conference, Asilomar, Pacific Grove, CA, U. S. A.

Eagle Yi-Kung Huang, Pao-Luh Tao, Jihn-Yih Li, and Jin-Chung Chen (2001) Endomorphin-1 and –2 induce naloxone-precipitated withdrawal syndromes in rats. 32nd International Narcotics Research Conference, Helsinki, Finland

E. Y.-K. Huang, J.-Y. Li, K.-W. Liang, C.-H. Wong, P. P.-C. Tan, R.-C. Huang, and J.-C. Chen (1999) The cardiovascular effects of PFRFamide and PFR(Tic)amide, a possible agonist and antagonist of neuropeptide FF (NPFF). Soc. Neurosci. Abstr., Vol. 25, Part 1, p. 958

J.-Y. Li, E. Y.-K. Huang, H.-L. Wang, C.-H. Wong, P. P.-C. Tan, and J.-C. Chen (1999) Depletion of spinal serotonin attenuates the rate of morphine tolerance in rats. Soc. Neurosci. Abstr., Vol. 25, Part 1, p. 176

J.-C. Chen, Y.-K. Huang, M. Y. Lin, and H. C. Hsieh (1999) The modulatory effect of endomorphin-1 and –2 on the induction and expression of amphetamine sensitization. Soc. Neurosci. Abstr., Vol. 25, Part 2, p. 2082

J.-C. Chen, J.-Y. Li, I.-K. Huang, and K.-W. Liang (1998) The significance of ventral pallidum on behavioral sensitization to amphetamine. Soc. Neurosci. Abstr., Vol. 24, Part 2, p. 1964