李世裕 Professor, Head      
Shih-Yu Lee

Position

Professor

Contact

+886-2-8792-3100 ext.18049
leeshihyuno1@mail.ndmctsgh.edu.tw

Publication

1. Wei-Hsiu Liu, Li-Shian Shi, Min-Chieh Chung, Tsu-Chung Chang, Shih-Yu Lee* (2019, Sep). Antcamphin M inhibits TLR4-mediated inflammatory responses by upregulating the Nrf2/HO-1 pathway and suppressing the NLRP3 inflammasome pathway in macrophages . The American Journal of Chinese Medicine, volume 47, issue 7, 1-16. (SCI, 3/26 in alternative and complementary medicine). 本人為通訊作者.

2. Kuen-Tze Lin, Shih-Yu Lee, Shao-Cheng Liu, Chih-Cheng Tsao, Sheng-Der Hsu, Wu-Chien Chien, Chi-Hsiang Chung, Wei-Kuo Chang, Yuan-Wu Chen, MD, Chun-Shu Lin (2019, Aug). Risk of Ocular Complications following Radiation Therapy in Patients with Nasopharyngeal Carcinoma. The Laryngoscope. (Accepted). (SCI).


3. Shih-Ming Chen, Kuen-Tze Lin, Yang-Hong Dai, Kwo-Tsao Chiang , Shih-Yu Lee* (2019, Jul). Fighter Pilots with Nasopharyngeal Carcinoma Successfully Returning to Flight After Radiotherapy: A Case Series. Military Medicine.(Accepted). (SCI). 本人為通訊作者.

4. KT Lin, SW Lai, SD Hsu, CY Fan, HJ Wang, PK Chang, WH Liu, YL Chen, IC Yen, SY Lee*. Shoulder Pain and Risk of Developing Hypertension and Cardiovascular Disease: A Nationwide Population-based Cohort Study in Taiwan. J Med Sci. Accepted. (Jan 7, 2019)本人為責任作者

5. Pi-Kai Chang, I-Chuan Yen, Wei-Cheng Tsai, Tsu-Chung Chang, Shih-Yu Lee*(2018, Aug). Protective effects of Rhodiola crenulata extract on hypoxia-induced endothelial damage via regulation of AMPK and ERK pathways. International Journal of Molecular Sciences. (Accepted). (IF=3.687, Ranking=90/292 in Biochemistry and Molecular biology).

6. Chih-Cheng Tsao, Shih-Yu Lee, Wei-Kuo Chang, Kuen-Tze Lin, Sheng-Der Hsu, Chen-Liang Tsai, Chun-Shu Lin (2018, Jun). Risk of gastric cancer following percutaneous endoscopic gastrostomy: A nationwide population-based cohort study . Medical Hypotheses. (Accepted). (SCI).

7. I-Chuan Yen, Li-Shian Shi, Min-Chieh Chung, Blerina Ahmetaj-Shala, TsuChung Chang, Shih-Yu Lee* (2018, Jun). Antrolone, a new benzoid from Antrodia cinnamomea mycelium, inhibits LPS-induced inflammatory response via balance of the NFκB and Nrf2 pathways in RAW 264.7 macrophage cells. The American Journal of Chinese Medicine, 46(6) 1-16.. (Accepted). (SCI, 3/26 in alternative and complementary medicine). 本人為通訊作者.

8. Kuen-Tze Lin, Tsu-Chung Chang, Feng-Yi Lai, Chun-Shu Lin, Hsing-Lung Chao, Shih-Yu Lee* (2018, Feb). Rhodiola crenulata attenuates gamma-ray induced cellular injury via modulation of oxidative stress in human skin cells. The American Journal of Chinese Medicine (AJCM), volume 46, issue 1 . (SCI, 3/26 in alternative and complementary medicine). 本人為通訊作者.

9. Shih-Yu Lee, W.-L. Chang, Z.-X. Li, N.S. Kirkby, Wei-ChengTsai, S.-F. Huang, C.-H. Oue, T.-C. Chang, (2018, Jan). Astragaloside VI and cycloastragenol-6-Obeta-D glucoside promote wound healing in in vitro and in vivo. , 38, 183-191. (SCI, 2/26, alternative and complementary medicine). 本人為第一作者.

10. 7. S.-Y. Lee, P.-Y. Chen, J.-C. Lin, N.S. Kirkby, C.-H. Ou, T.-C. Chang, (2017, Dec). Melaleuca alternifolia concentrate induces heme oxygenase-1 expression in murine RAW264.7 cells through activation of the Nrf2-ARE pathway. The American Journal of Chinese Medicine, 45(8), 1-18. (SCI, 3/26 in alternative and complementary medicine). 本人為第一作者.

11. Sheng-Der Hsu, Shih-Yu Lee, Kuen-Tze Lin, Chun-Shu Lin, Wu-Chien Chien, Cheng-Jueng Chen, Chi-Hsiang Chung and Chang W.-K. (2017, Dec). Risk of infertility following pelvic angiographic embolization in female patients with pelvic fractures: A nationwide population-based cohort study in Taiwan. PloS one , 12(12) (2017) e0174733.. (SCI).

12. Li-Yen Huang, I-Chuan Yen, Wei-Cheng Tsai, Blerina Ahmetaj-Shala, TsuChung Chang, Chien-Sung Tsai and Shih-Yu Lee (2017, Sep). Rhodiola crenulata Attenuates High Glucose Induced Endothelial Dysfunction in Human Umbilical Vein Endothelial Cells.. The American Journal of Chinese Medicine , 45 (6), 1-16. (SCI, 3/26 in alternative and complementary medicine). 本人為通 訊作者.

13. Shih-Yu Lee, Wei-Cheng Tsai, Jung-Chun Lin, Blerina Ahmetaj-Shala, Su-Feng Huang, Wen-Liang Chang, Tsu-Chung Chang (2017, Sep). Astragaloside II promotes intestinal epithelial repair by enhancing L-arginine uptake and activating the mTOR pathway. Scientific Reports, 7; 12302. (SCI, 10/64 Multidisciplinary Science). 本人為第一作者.

14. I-Chuan Yen, Shih-Yu Lee, Kuen-Tze Lin, Feng-Yi Lai, Mao-Tien Kuo, Chang W-L (2017, May). In Vitro Anticancer Activity and Structural Characterization of Ubiquinones from Antrodia cinnamomea Mycelium. Molecules, 22(747):1-12..

15. Hsu, S.-W.; Chang, T.-C.; Wu, Y.-K.; Lin, K.-T.; Shi, L.-S.; Lee, S.-Y* (2017, Jan). Rhodiola crenulata extract counteracts the effect of hypobaric hypoxia in rat heart via redirection of the nitric oxide and arginase 1 pathway.. BMC Complementary and Alternative Medicine, 17(1) . (SCI, Ranking/Category=6/26, INTEGRATIVE COMPLEMENTARY MEDICINE). MOST 104-2320-B-016-003. 本人為通訊作者.

16. Lin K-T, Hsu S-W, Lai F-Y, Chang T-C, Shi L-S, Lee S-Y (2016, May). Rhodiola crenulata extract regulates hepatic glycogen and lipid metabolism via activation of the AMPK pathway. BMC Complementary and Alternative Medicine , 2016, 16(1). 1-10. (SCI, 6/26, integrative and complementary medicine). MOST 104-2320-B-016-003. 本人為通訊作者.


17. Lin, S.; Gou, G.; Hsia, C.; Ho, C.; Huang, K.; Wu, Y.; Lee, S.; Chen, Y (2016, May). Simulated Microgravity Disrupts Cytoskeleton Organization and Increases Apoptosis of Rat Neural Crest Stem Cells via Upregulating CXCR4 Expression and RhoA-ROCK1-p38 MAPK-p53 Signaling. . Stem Cells Dev .

18. Lin KT, Lin CS, Lee SY, Huang WY, Chang WK (2016, Mar). Risk of Esophageal Cancer Following Percutaneous Endoscopic Gastrostomy in Head and Neck Cancer Patients: A Nationwide Population-Based Cohort Study in Taiwan. Medicine, 95(9):e2958..

19. Min-Hui Li, Yi-Ling Chen, Kuen-Tze Lin, Shih-Wei Hsu, Yi-Hui Chen, Shih-Yu Lee* (2015, Dec). TAZ is Associated with Poor Osteoblast Differentiation of Mesenchymal Stem Cells under Simulated Microgravity. Journal of Medical Sciences, 35 (6). 本人為通訊作者. 國防醫學院期刊.


20. Ju, D.-T., Hsu, S.-W., Chao, H.-L., Lin, K.-T., Chou, Y.-C., Lo, C.-H., Lee, S.-Y., Huang, W.-Y., Lin, C.-S., Lin, C.-M., Fan, C.-Y. (2015, Aug). Pain relief following spinal lesion treatment with stereotactic radiosurgery: Clinical experience in 65 cases.. Journal of Medical Science, 35(4):162-168. 國防醫學院 期刊.

21. Lee S-Y, Lai F-Y, Shi L-S, Chou Y-C, Yen IC, Chang T-C. (2015, Mar). Rhodiola crenulata extract suppresses hepatic gluconeogenesis via activation of the AMPK pathway.. Phytomedicine, 22, 477-486. (SCI, 2/26. INTEGRATIVE & COMPLEMENTARY MEDICINE). 本人為第一作者.

22. Chiang, K.-T., Lee, S.-Y., Chu, H. (2015, Jan). Dermatofibrosarcoma protuberans, a rare but locally aggressive tumor on finger: clinical and aeromedical considerations.. Case Reports in Plastic Surgery and Hand Surgery.

23. Shih-Yu Lee, Li-Shian Shi, Hsin Chu, Min-Hui Li, Cheng-Wen Ho, Feng-Yi Lai, Chih-Yang Huang, and Tsu-Chung Chang* (2013, May). Rhodiola Crenulata and its Bioactive Components, Salidroside and Tyrosol, Reverse the HypoxiaInduced Reduction of Plasma Membrane-Associated Na,K-ATPase expression via Inhibition of ROS-AMPK-PKCζ Pathway . Evidence-Based Complementary and Alternative Medicine (eCAM) , Volume 2013, Article ID 284150, 15 pages.. (SCI, 6/22 in INTEGRATIVE & COMPLEMENTARY MEDICINE). 本人為第 一作者.

24. Shih-Yu Lee, Min-Hui Li, Li-Shian Shi, Hsin Chu, Cheng-Wen Ho, Tsu-Chung Chang* (2013, Mar). Rhodiola Crenulata Extract Alleviates Hypoxic Pulmonary Edema in Rats. . Evidence-Based Complementary and Alternative Medicine (eCAM) , Article ID 718739, 9 pages.. (SCI, 6/22 in INTEGRATIVE & COMPLEMENTARY MEDICINE). 本人為第一作者.

25. Hsin Chu, Min-Hui Li, Yu-Cheng Huang, Shih-Yu Lee. (2013). Simultaneous transcutaneous electrical nerve stimulation mitigates simulator sickness symptoms in healthy adults: a crossover study. BMC Complement Altern Med , 13:84, 1