研究興趣

腫瘤幹細胞
神經科學

研究論文

Kao Y,Tsai WC,Chen SH,Hsu SY,Huang LC,Chang CJ,Huang SM,*Hueng DY(2021)Shugosin 2 is biomarker for pathological grading and survival prediction in patients with gliomas. Scientific Reports (SCI,IF 4.379, Rank 23.3%, Multidisciplinary Sciences)

Luo SM,Wu YP,Huang LC,Huang SM,*Hueng DY(2021,Aug).
The anti-cancer effect of four curcumin analogues on human glioma cells. OncoTargets and Therapy, 2021 Aug 4;14:4345-4359.(SCI, IF 4.147, Rank 32.7%, Biotechnology & Applied Microbiology)

Chen SH, Lin HH, Li YF, Tsai WC, *Hueng DY (2021, May). Clinical Significance and Systematic Expression Analysis of the Thyroid Receptor Interacting Protein 13 (TRIP13) as Human Gliomas Biomarker. Cancers, 2021, 13, 2338. https://doi.org/10.3390/ cancers13102338. (SCI, IF 6.639, Rank 21.1%, Oncology).

Luo SM, Tsai WC, Tsai CK, Chen Y, *Hueng DY (2021, Mar). ARID4B knockdown suppresses PI3K/AKT signaling and induces apoptosis in human glioma cells. OncoTargets and Therapy, 2021:14 1843–1855 . (SCI, IF 4.147, Rank 32.7%, Biotechnology & Applied Microbiology).

Lin HH, Tsai WC, Tsai CK, Chen SH, Huang LC, *Hueng DY, *Hung KC (2021, Feb). Overexpression of Cell-Surface Marker SLC16A1 Shortened Survival in Human High-Grade Gliomas. Journal of Molecular Neuroscience, 2021. doi:10.1007/s12031-021-01806-w. (SCI, IF 3.444,Neurosciences).

Hsu WC,Sugiarto T,Liao YY,Lin YJ,Yang FC,Hueng DY,Sun CT,Chou KN(2021).Can Trunk Acceleration Differentiate Stroke Patient Gait Patterns Using Time-and Frequency-Domain Features.Applied Sciences

Chuang JMJ, *Hueng DY (2021, Mar). Treatment of MGMT positive glioblastoma. Journal of Neurosurgery. (Accepted). (SCI).

Tsai CK, Huang LC, Wu YP, Kan IY, *Hueng DY (2019, Dec). SNAP reverses temozolomide resistance in human glioblastoma multiforme cells through downregulation of MGMT. FASEB Journal(IF: 5.391, Ranking 9.2%, 8/87,
Biology), 33(12):14171-14184

Chi KC, Tsai WC, Wu CL, Lin TY, *Hueng DY (2019, Jun). An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis. Molecular Neurobiology(IF: 4.586, Ranking 21.3%, Neurosciences)

Lin BJ, Ju DT, Hsu TH, Chung TT, Liu WH, Hueng DY, Chen YH, Hsia CC, Ma HI, Liu MY, Hung HC, Tang CT (2019, Jun). Endoscopic transorbital approach to anterolateral skull base through inferior orbital fissure: a cadaveric study. Acta
Neurochir (Wien), doi: 10.1007/s00701-019-03993-3. (SCI).

Syu WZ, Hueng DY, Chen WL, Chan JY, Chen SG, Huang SM (2019, May). Adipose-Derived Neural Stem Cells Combined with Acellular Dermal Matrix as a Neural Conduit Enhances Peripheral Nerve Repair. Cell Transplantation, doi: 10.1177/0963689719853512. (SCI).

Wang CC, Hueng DY, Huang AF, Chen WL, Huang SM, Chan JY (2019, Mar). CD164 regulates proliferation, progression, and invasion of human glioblastoma cells. Oncotarget, 10(21):2041-2054.

Lin BJ, Hong KT, Chung TT, Liu WH, Hueng DY, Chen YH, Ju DT, Ma HI, Liu MY, Hung HC, Tang CT (2019, Feb). Endoscopic transorbital transtentorial approach to middle incisural space: preclinical cadaveric study. Acta Neurochir
(Wien), doi: 10.1007/s00701-019-03831-6. (SCI).

Huang ZY, Hueng DY, Tsai WC (2019, Jan). The Application of FOXO1A Expression Predicts Aggressive Behavior and Poor Prognosis in Gliomas. Appl Immunohistochem Mol Morphol, doi: 10.1097/PAI.0000000000000710. (SCI).

Ke HH, Hueng DY, Tsai WC (2019, Jan). Low expression of pentraxin 3 and nuclear factor-like 2 implying a relatively longer overall survival time in gliomas. Chin J Physiol, 62(1):35-43. (SCI).

Lin PC, Chen CY, Chu CW, Tai YM, Hueng DY, Tzeng NS (2019, Jan). Psychotic Symptoms Related to the Prophylactic Use of Levetiracetam After Brain Surgery. Am J Ther, doi: 10.1097/MJT.0000000000000940. (SCI).

Liu HW, Su YK, Bamodu OA, Hueng DY, Lee WH, Huang CC, Deng L, Hsiao M, Chien MH, Yeh CT, Lin CM (2018, Dec). The Disruption of the β- Catenin/TCF-1/STAT3 Signaling Axis by 4-Acetylantroquinonol B Inhibits the Tumorigenesis and Cancer Stem-Cell-Like Properties of Glioblastoma Cells, In Vitro and In Vivo. Cancers (Basel), pii: E491. doi: 10.3390/cancers10120491.(SCI).

Lin BJ, Hong KT, Lin C, Chung TT, Tang CT, Hueng DY, Hsia CC, Ju DT, Ma HI, Liu MY, Chen YH (2018, Nov). Impact of global spine balance and cervical regional alignment on determination of postoperative cervical alignment after laminoplasty. Medicine (Baltimore), 97(45):e13111. (SCI).

Lin MC, Li CZ, Hsieh CC, Hong KT, Lin BJ, Lin C, Tsai WC, Lee CH, Lee MG, Chung TT, Tang CT, Ju DT, Ma HI, Liu MY, Chen YH, *Hueng DY (2018, Nov). Preoperative grading of intracranial meningioma by magnetic resonance spectroscopy (1H-MRS). PLoS One, 2018 19;13(11):e0207612. (SCI)

Chen YH, Hueng DY, Tsai WC (2018, Oct). Proteolipid Protein 2 Overexpression Indicates Aggressive Tumor Behavior and Adverse Prognosis in Human Gliomas. Int J Mol Sci, 19(11). pii: E3353. (SCI).

Tsai WC, Hueng DY, Lin CR, Yang TCK, Nieh S, Gao HW (2018, Apr). Applying DDX3X Biomarker to Discriminate Atypical from Benign Meningiomas in Tissue Microarray. Appl Immunohistochem Mol Morphol, 2018;26(4):263-267.

Ho HH, Li YH, Lee JC, Wang CW, Yu YL, Hueng DY, Ma HI, Hsu HH, Juan CJ (2018, Feb). Vestibular schwannomas: Accuracy of tumor volume estimated by ice cream cone formula using thin-sliced MR images. PLoS One, 2018;13(2):e0192411

Tsai CK, Huang LC, Tsai WC, Huang SM, Lee JT, *Hueng DY (2018, Feb). Overexpression of PLOD3 promotes tumor progression and poor prognosis in gliomas. Oncotarget, 2018;9(21):15705-15720

Li CZ, Liu FC, Li CC, Lin MC, Hsieh CC, Lin BJ, Chen NF, Chen CL, Chung TT, Tang CT, Hueng DY, Ju DT, Ma HI, Liu MY, Lu CH, Chen YH (2018, Jan). The Efficacy of Therapeutic Plasma Exchange in Antiphospholipid Antibodypositive Patients With Spontaneous Intracerebral Hemorrhage and High D-dimer Levels. Neurologist, 2018;23(1):7-11.

Yang YJ, Chien WC, Chung CH, Hong KT, Yu YL, Hueng DY, Chen YH, Ma HI, Chang HA, Kao YC, Yeh HW, Tzeng NS (2018, Jan). Risk of Erectile Dysfunction After Traumatic Brain Injury: A Nationwide Population-Based Cohort study in Taiwan. Am J Mens Health, 2018 Jan 1:1557988317750970

Chang YL, Huang LC, Chen YC, Wang YW, *Hueng DY, *Huang SM (2017, Nov). The synergistic effects of valproic acid and fluvastatin on apoptosis induction in glioblastoma multiforme cell lines. Int J Biochem Cell Biol, 92:155-163. (SCI, IF: 3.247, Ranking 32.8%, Biochemistry & Molecular Biology)

Hueng DY, Hsieh CH, Cheng YC, Tsai WC, Chen Y (2017, Mar). Cordycepin inhibits migration of human glioblastoma cells by affecting lysosomal degradation and protein phosphatase activation. J Nutr Biochem, 41:109-116. (SCI).

Li CZ, Li CC, Hsieh CC, Lin MC, Hueng DY, Liu FC, Chen YH (2017, Jan). Fatal antiphospholipid syndrome following endoscopic transnasaltranssphenoidal surgery for a pituitary tumor: A case report. Medicine (Baltimore), 96(1):e5774

Yu YL, Yang YJ, Lin C, Hsieh CC, Li CZ, Feng SW, Tang CT, Chung TT, Ma HI, Chen YH, *Ju DT, *Hueng DY (2017, Jan). Analysis of volumetric response of pituitary adenomas receiving adjuvant CyberKnife stereotactic radiosurgery with the application of an exponential fitting model. Medicine (Baltimore), 96(4):e4662. (SCI)

Tsai CK, Lee JT, Chen YH, Liang CS, Lin CC, Chang NW, Liu C, Chou CH, Chen GS, Liu FC, Lin TY, *Hueng DY (2016, Dec). Cell Division Cycleassociated 7-like Gene: A Novel Biomarker for Adverse Survival in Human High-grade Gliomas. Journal of Medical Sciences, 36(6):224?228.


Lin BJ, Chung TT, Lin MC, Lin C, Hueng DY, Chen YH, Hsia CC, Ju DT, Ma HI, Liu MY, Tang CT (2016, Oct). Quantitative analysis of anatomical relationship between cavernous segment internal carotid artery and pituitary macroadenoma. Medicine (Baltimore), 95(41):e5027. (SCI).

Tsai CK, Kao TW, Lee JT, Wu CJ, Hueng DY, Liang CS, Wang GC, Yang FC, Chen WL (2016, Sep). Increased risk of cognitive impairment in patients with components of metabolic syndrome. Medicine (Baltimore), 2016 Sep;95(36):e4791. (SCI).

Lin CK, Ting CC, Tsai WC, *Chen YW, *Hueng DY (2016, Aug). A tissue microarray study of toll-like receptor 4, decoy receptor 3, and external signal regulated kinase 1/2 expressions in astrocytoma. Indian J Pathol Microbiol, 59(3):294-300 . (SCI).

Cheng CP, Huang LC, Chang YL, Hsieh CH, *Huang SM, *Hueng DY (2016, Jul). The mechanisms of malic enzyme 2 in the tumorigenesis of human gliomas.Oncotarget, 7(27):41460-41472. (SCI)

Cheng YC, Ding YM, Hueng DY, Chen JY, Chen Y (2016, Jul). Caffeine suppresses the progression of human glioblastoma via cathepsin B and MAPK signaling pathway. J Nutr Bilchem, 33:63-72. (SCI)

Tsai WC, Hueng DY, Nieh S, Gao HW (2016, Jul). ARID4B is a Good Biomarker to Predict Tumor Behavior and Decide WHO Grades in Gliomas and Meningiomas. Journal of Clinical Pathology. (SCI)

Feng SW, Chen Y, Tsai WC, Chiou HY, Wu ST, Huang LC, Lin C, Hsieh CC, Yang YJ, *Hueng DY (2016, Jun). Overexpression of TELO2 decreases survival in human high-grade gliomas. Oncotarget. (SCI)

Tsai WC, Hueng DY, Lin CR, Yang TCK, Gao HW (2016, May). Nrf2 expressions correlate with WHO grades in gliomas and meningiomas. International Journal of Molecular Sciences, 17(5). pii: E722. (SCI)

Cheng YC, Hueng DY, Huang HY, Chen JY, Chen Y (2016, Apr). Magnolol and honokiol exert a synergistic anti-tumor effect through autophagy and apoptosis in human glioblastomas. Oncotarget , doi: 10.18632/oncotarget.8674. (SCI)

Chung TT, Hueng DY, Lin SC (2015, Dec). Hybrid strategy of Two-level Cervical Artificial Disc and Intervertebral Cage: Biomechanical Effects onTissues and Implants. Medicine (Baltimore), 94(47):e2048. (SCI)

Chou CH, Fan HC, Hueng DY (2015, Nov). Potential of Neural Stem Cell-Based Therapy for Parkinson's Disease. Parkinson's Disease , Volume 2015, Article ID 571475, 9 pages. (SCI)

Lai SF, Ko BH, Chien CC, Chang CJ, Yang SM, Chen HH, Petibois C,*Hueng DY, Ka SM, Chen A, Margaritondo G, *Hwu Y (2015, Nov). Gold nanoparticles as multimodality imaging agents for brain gliomas. J Nanobiotechnology (SCI)

Lin BJ, Chou KN, Feng SW, Ju DT, Ma HI, *Hueng DY (2015, Oct). Role of Post-Decompressive Hydrocephalus in Patients with Malignant Cerebral Infarction . Turk Neurosurg, 25(5):742-748. (SCI, 176/198, 88%, Surgery).

*Hueng DY, Tsai WC, Chiou HY, Feng SW, Lin C, Li YF, Huang LC, Lin MH (2015, Jul). DDX3X biomarker correlates with poor survival in human gliomas. International Journal of Molecular Sciences, 16:15578-15591. (SCI, IF = 2.862,45/157, 28.7%, Chemistry, Multidisciplinary).

Chen CC, Hsu YH, Jayaseema DM, Chen JY, *Hueng DY, *Chang C (2015, Jul). White matter tracts for the trafficking of neural progenitor cells characterized by cellular MRI and immunohistology: the role of CXCR12/CXCR4 signaling.Brain Structure and Function, 220: 2073-2085. (SCI, IF: 3.622, 1/21, 4.76% in Anatomy & Morphology).

Chiou HY, Lai WK, Huang LC, Huang SM, Chueh SH, Ma HI, *Hueng DY. (2015) Valproic acid promotes radiosensitization in meningioma stem-like cells. Oncotarget. 2015 Mar 29. Impact factor: 6.63 (17/202, 8.4%, Oncology)

Tsai WC, Hueng DY, Lin CK. (2015) Nuclear overexpression of urocortin discriminates primary brain tumors from reactive gliosis. Acta Pathologica, Microbiologica, ET Immunologica Scandinavica (APMIS). APMIS. 2015 Apr 23. doi: 10.1111/apm.12374. Impact factor: 1.922 (43/76, 56.6%, Pathology)

*Hueng DY, Sytwu HK. (2015) Letter to the Editor: Fusion antibody Fc-endostatin. Journal of Neurosurgery 2015 Feb. 27 [SCI]

Zheng ZH, Lin Y, Su PS, Wang PW, Tsai WT, Hueng DY. (2015) Letter to the Editor. Trigeminal neuralgia Journal of Neurosurgery. DOI: 10.3171/2012.2.JNS122202 [SCI]

Chen CH, Lin FS, Liao WN, Liang SL, Chen MH, Chen YW, Lin WY, Hsu MH, Wang MY, Peir JJ, Chou FI, Chen CY, Chen SY, Huang SC, Yang MH, Hueng DY, Hwu Y, Yang CS, Chen JK. (2015) Establishment of a Trimodality Analytical Platform for Tracing, Imaging and Quantification of Gold Nanoparticles in Animals by Radiotracer Techniques.
Analytical Chemistry. 87(1) :601-608. PMID :25424326. Impact factor: 5.825 (4/76, 5.26%, Chemistry, Analytical)

【2014】30篇

Cheng YS, Lin C, Cheng YP, Yu EL, Tang CT, *Hueng DY. (2014) Epithelial cell transformation sequence 2 is a potential biomarker of unfavorable survival in human gliomas. Neurology India 62(4):406-409. (SCI)

Lin BJ, Chou KN, Lin C , Lee MS, Feng SW, Ju DT, Ma HI, *Hueng DY. (2014) Open-Door Laminoplasty Modulates the Cervical Spinal Cord Morphology. Turkish Neurosurgery (SCI)【Accepted】

Chen CC, Hsu YH, Jayaseema DM, Chen JY, *Hueng DY, *Chang C (2014). White matter tracts for the trafficking of neural progenitor cells characterized by cellular MRI and immunohistology: the role of CXCR12/CXCR4 signaling. Brain Structure and Function. DOI: 10.1007/s00429-014-0770-4. (SCI IF= 7.837 JCR2012 , 1/21, Anatomy & Morphology).

Chan TM, Chen JY, Ho LI, Lin HP, Hsueh KW, Liu DD, Chen YH, Hsieh AC, Tsai NM, Hueng DY, Tsai ST, Chou PW, Lin SZ, Harn HJ (2014). ADSC Therapy in Neurodegenerative Disorders. Cell Transplant. 23(4-5):549-57. (2013 IF=3.570, 5/26 = 19.2%, Transplantation)

Wang CW, Liu YJ, Lee YH, Hueng DY, Fan HC, Yang FC, Hsueh CJ, Kao HW, Juan CJ, Hsu HH (2014, Jul). Hematoma Shape, Hematoma Size, Glasgow Coma Scale Score and ICH Score: Which Predicts the 30-Day Mortality Better for Intracerebral Hematoma. PLoS One. 9(7):e102326. (SCI, 7/56, 12.5%, Multidisciplinary Sciences). NSC 101-2314-B-016-031-MY2.

Chen YW, Huang HS, Shieh YS, Ma KH, Huang SH, Hueng DY, Sytwu HK, Lin GJ A novel compound NSC745885 exerts an anti-tumor effect on tongue cancer SAS cells in vitro and in vivo. PLoS One. 2014 Aug 15;9(8):e104703.

Lin BJ, Chou KN, Kao HW, Lin C, Tsai WC, Feng SW, Lee MS, *Hueng DY. (2014) Correlation between Magnetic Resonance Imaging Grading and Pathologic Grading in Meningioma. Journal of Neurosurgery 121(5):1201-1208. (SCI IF: 3.148, ranking: 21/199=10.6%) (2013 IF=3.227, 21/202=10.4%, Surgery)

He WJ, Hosseinkhani H, Mohammadinejad R, Roveimiab Z, Hueng DY, Ou KL, Domb AJ. (2014) Polymeric Nanoparticles for Therapy and Imaging. Polymers for Advanced Technologies. DOI: 10.1002/pat.3381 (SCI IF: 1.964, ranking: 33/82=40.24%, POLYMER SCIENCE)

Hosseinkhani H, Abedini F, Hueng DY, Ou KL, Domb AJ. (2014) Polymers in Gene Therapy Technology. Polymers for Advanced Technologies. 【Accepted】(SCI IF: 1.964, ranking: 33/82=40.24%, POLYMER SCIENCE)

Lin BJ, Chou KN, Lin C, Lee MS, Ma HI, *Hueng DY. (2014) The response of ventriculoperitoneal shunt to post-decompressive hydrocephalus. Turkish Neurosurgery (SCI) 【Accepted】

Yang CW, Hsu SN, Liu JS, *Hueng DY. (2014) Serratia Marcescens Spinal Epidural Abscess after Acupuncture: A Case Report. Internal Medicine. 53(15):1665-8 [SCI]
Chen JH, Chen KY, Hueng DY, Jin JS. Secondary pulmonary conventional chordoma arising from primary sarcomatoid chordoma of the sacrum: A case report. Oncology Letters. 8(1):208-210 [SCI 0.237]

Hueng DY, Chung TT, Chuang WH, Hsu CP, Chou KN, Lin SC. (2014) Biomechanical Effects of Cage Positions and Facet Fixation on Initial Stability of the Anterior Lumbar Interbody Fusion Motion Segment. Spine. 39(13):E770-6 [SCI]

Cheng YP, Lin C, Lin PY, *Chen CM, *Hueng DY. (2014) Midkine expression in high grade gliomas – correlation of this novel marker with proliferation and survival in human gliomas. Surgical Neurology International. 5:78 [SCI]

Chen Y, Yang SH, Hueng DY, Syu JP, Liao CC, Wu YJ. (2014) Cordycepin induces apoptosis of C6 glioma cells through the adenosine 2A receptor-p53-caspase-7-PARP pathway. Chemico-Biological Interactions. 216:17-25 [SCI 2.967, 28.7% Pharmacology]

Cheng YP, Lee KW, Lin PY, Huang APH, Cheng CY, Ma HI, *Chen CM, *Hueng DY. (2014) Full-endoscopic interlaminar removal of chronic lumbar epidural hematoma after spinal manipulation. Technical Note. Surgical Neurology International. 5:55 [SCI]

Cheng YP, Lin PY, Huang APH, Cheng CY, *Chen CM, *Hueng DY. (2014) Durotomy repair in minimally invasive transforaminal lumbar interbody fusion by nonpenetrating clips. Technical Note. Surgical Neurology International. 5:36 [SCI]

Chou KN, Lin BJ, Wu YC, Liu MY, *Hueng DY. (2014) Progressive kyphosis after vertebroplasty in osteoporotic vertebral compression fracture. Spine. 39(1):68-73. [SCI]

Ma HI, Hueng DY, Shui HA, Han JM, Wang CH, Lai YH, Cheng SY, Xiao Xiao, Chen MT, Yang YP. (2014) Intratumoral decorin gene delivery by AAV vector inhibits brain glioblastomas and prolongs survival of animals by inducing cell differentiation. International Journal of Molecular Sciences 15(3):4393-4414. [SCI]

Chen YW, Lin GJ, Hueng DY, Huang SH, Chia WT, Shieh YS, Ma KH, Sytwu HK. (2014) Enhanced Anti-Tumor Activity of Triptolide in Combination with Irradiation for the Treatment of Oral Cancer. PLANTA MEDICA. 80(4):255-61. [SCI]

Cheng YP, Feng SW, Chen CM, *Hueng DY. (2014) Complex regional pain syndrome. Journal of Neurosurgery: Spine. 20(4):473 [SCI]

Yu TY, Chen CH, Hua MW, Lee CC, *Hueng DY. (2014) Subarachnoid hemorrhage. Journal of Neurosurgery. 120(1):285. [SCI]

Hueng DY, Lin GJ, Sytwu HK. (2014) Glioma immunoenvironment. Journal of Neurosurgery. 120(4):1012-1203

Peng YL, Liu NT, Peng DY, Hsieh YT, *Hueng DY. (2014) Intracranial pressure monitoring and traumatic brain injury. Journal of Neurosurgery. 120(3):779. [SCI]
Hueng DY, Sytwu HK. (2014)Vestibular schwannoma growth and hearing loss. Journal of Neurosurgery 120(3)786. [SCI]

Feng SW, Sytwu HK, *Hueng DY. (2014) Cell transplantation. Journal of Neurosurgery. 120(2):574. [SCI]

*Hueng DY, Sytwu HK. (2014) Blood-brain barrier. Journal of Neurosurgery. 120(1):290. [SCI]

Chen YC, Chang WC, Huang CY, *Hueng DY. (2014) Cerebrospinal fluid leak. Journal of Neurosurgery. 120(2):575. [SCI]

Huang LC, *Hueng DY. (2014) CD97 and glioma invasion. Journal of Neurosurgery. 120(2):579-580. [SCI]

Chou KN, Tsai GH, Huang WY, *Hueng DY. (2014) Morbidity in vestibular schwannoma surgery. Journal of Neurosurgery.2014;120(3):785-786. [SCI]