聯絡方式

電話:(02)2736-1661 ext.6187
Email:wcc@tmu.edu.tw

專長學科

學門領域:藥物基因體學、鈣離子通道
學術專長:基因定序、基因型鑑定

發表著作

1. 2019 Hsing-Fang Lu,Kuo-Sheng Hung,Hou-Wei Chu,Henry Sung-Ching Wong,Jihye Kim,Bo Youl Choi, Mi Kyung Kim, Yu-Ting Tai, Shiro Ikegawa, Er-Chieh Cho, Wei-Chiao Chang. Meta-analysis of genome-wide association studies identifies three loci associated with stiffness index of the calcaneus . Journal of Bone and Mineral Research .2019

2. 2019 Chang CM,Wong HS,Huang CY,Hsu WL,Maio ZF,Chiu SJ，Tsai YT， Chen BK，Wan YY，Wang JY，Chang WC. Functional Effects of let-7g Expression in Colon Cancer Metastasis. . Cancers (Basel) .2019 ;(11)

3. 2019 Kao CC,Cheng SY,Wang YJ,Chien SC,Hsu YW,Wu MY, Lu HF, Nam S, Sun T, Wu MS, Chang WC. Association of endothelin genetic variants and hospitalized infection complications in end-stage renal disease (ESRD) patients. . BMC Nephrology .2019 ;(20):203

4. 2019 Wong JH,Wang YS,Nam S,Ho KH,Chang CM,Chen KC, Chen YF, Chang WC. Phthalate plasticizer di(2-ethyl-hexyl) phthalate induces cyclooxygenase-2 expression in gastric adenocarcinoma cells. . ENVIRONMENTAL TOXICOLOGY .2019 ;(34):1191-1198

5. 2019 Chang CM,Hsu YW,Wong HS,Wei JC,Liu X,Liao HT, Chang WC.. Characterization of T-Cell Receptor Repertoire in Patients with Rheumatoid Arthritis Receiving Biologic Therapies . Disease Markers .2019 ;(2019)

6. 2019 Hung CS,Huang CY,Hsu YW,Makondi PT,Chang WC,Chang YJ, Wang JY, Wei PL. HSPB1 rs2070804 polymorphism is associated with the depth of primary tumor . Journal of cellular biochemistry. .2019

7. 2019 Kuo CN,Liao YM,Kuo LN,Tsai HJ,Chang WC,Yen Y. Cancers in Taiwan: Practical insight from epidemiology, treatments, biomarkers, and cost. . J Formos Med Assoc .2019

8. 2019 Chen YC,Wu MY,Hu PJ,Chen TT,Shen WC,Chang WC, Wu MS. Effects and Safety of an Oral Adsorbent on Chronic Kidney Disease Progression: A Systematic Review and Meta-Analysis. . Journal of clinical medicine .2019 ;(8)

9. 2019 Wong HS,Lin YJ,Lu HF,Liao WL,Chen CH,Wu JY, Chang WC, Tsai FJ.. Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning. . J Biomed Sci .2019 ;(26)

10. 2019 Chen HF,Shiao CY,Wu MY,Lin YC,Chen HH,Chang WC, Wu MS, Kao CC, Tsai IL.. Quantitative determination of human IgA subclasses and their Fc-glycosylation patterns in plasma by using peptide analogue internal standard and ultra-high-performance liquid chromatography-triple quadrupole mass spectrometry. . Rapid Commun Mass Spectrom. .2019

11. 2019 Wang YJ,Chang WC,Wu CC,Chiang YH,Chiu WT,Chen KY, Chang WP.. Increased short- and long-term risk of sleep disorders in people with traumatic brain injury. . Neuropsychol Rehabil. .2019

12. 2019 Wakabayashi G,Lee YC,Luh F,Kuo CN,Chang WC,Yen Y. Development and clinical applications of cancer immunotherapy against PD-1 signaling pathway . Journal of Biomedical Science .2019 ;(26):98

13. 2019 Wang YJ,Wong HS,Wu CC,Chiang YH,Chiu WT,Chen KY, Chang WC. The functional roles of IGF-1 variants in the susceptibility and clinical outcomes of mild traumatic brain injury . Journal of Biomedical Science .2019 ;(26):94

14. 2019 Chen WC,Chou WH,Chu HW,Huang CC,Liu X,Chang WP, Chou YH, Chang WC. The rs1256328 (ALPL) and rs12654812 (RGS14) Polymorphisms are Associated with Susceptibility to Calcium Nephrolithiasis in a Taiwanese population. . Sci Rep .2019 ;(9):17296

15. 2019 Irham LM,Wong HS,Perwitasari DA,Chou WH,Yang HI,Chang WC. Single-nucleotide polymorphism of rs7944135 (macrophage-expressed gene 1) is associated with hepatitis B surface antigen seroclearance in chronic hepatitis B infection . Medicine (Baltimore) .2019 ;(98)

16. 2018 Wang YJ,Chen KY,Kuo LN,Wang WC,Hsu YW,Wong HS, Lin CM, Liao KH, Zhang YF, Chiang YH, Chang WC. The association between BDNF Val66Met polymorphism and emotional symptoms after mild traumatic brain injury. . BMC medical genetics .2018 ;(19):13

17. 2018 Chuang SY,Hsu PF,Lin FJ,Huang YW,Wang GZ,Chang WC, Tsai HJ. Association between nonsteroidal anti-inflammatory drugs and atrial fibrillation among a middle-aged population: a nationwide population-based cohort. . British journal of clinical pharmacology. .2018

18. 2018 Kuo CN,Pan JJ,Huang YW,Tsai HJ,Chang WC. Association between Nonsteroidal Anti-inflammatory Drugs and Colorectal Cancer: a Population-based Case-control Study. . Cancer Epidemiol Biomarkers Prev. .2018

19. 2018 Ho KH,Chang CK,Chen PH,Wang YJ,Chang WC,Chen KC. miR-4725-3p targeting Stim1 signaling is involved in xanthohumol inhibition of glioma cell invasion. . J Neurochem. .2018

20. 2018 Wong HS,Chang WC. Losses of Cytokines and Chemokines are Common Genetic Features of Human Cancers: the Somatic Copy Number Alterations are Correlated with Patient Prognoses and Therapeutic Resistance. . Oncoimmunology. .2018 ;(7):e1468951

21. 2018 Hsing-Fang Lu,Henry Sung-Ching Wong,Ben-Kuen Chen,Hsien-Tzung Liao,Yu-Wen Hsu,Shiro Ikegawa, Er-Chieh Cho, Kuo-Sheng Hung, Wei-Chiao Chang. Integrative genomic analysis for the functional roles of ITPKC in bone mineral density . Biosci Rep. .2018 ;(38)

22. 2018 Tsung‐Chieh Yao,Ren‐Hua Chung,Chung‐Yen Lin,Pei‐Chien Tsai,Wei‐Chiao Chang, Kuo‐Wei Yeh, Ming‐Han Tsai, Sui‐Ling Liao, Man‐Chin Hua , Shen‐Hao Lai, Li‐Chen Chen, Su‐Wei Chan, Ya‐Wen Yu, Jing‐Ya Hsu, Su‐Ching Chang, Wen‐Chih Cheng, Donglei Hu, Xiumei Hong, Esteban G. Burchard , Xiaobin Wang, Jung‐Ying Tzeng, Hui‐Ju Tsai, Jing‐Long Huang. Genetic loci determining total immunoglobulin E levels from birth through adulthood. . Allergy .2018

23. 2018 Chao-Yuan Yu,Wei-Chiao Chang,Jia-Huei Zheng,Wei-Hung Hung,Er-Chieh Cho. Transforming growth factor alpha promotes tumorigenesis and regulates epithelial-mesenchymal transition modulation in colon cancer. . Biochem Biophys Res Commun .2018 ;(506):901-906

24. 2018 Chih-Chin Kao, Jia-Sin Liu, Yu-Kang Chang, Ming-Huang Lin,Yen-Chung Lin,Hsi-Hsien Chen, Wei-Chiao Chang, Chih-Cheng Hsu, Mai-Szu Wu. Cancer and mTOR inhibitors in kidney transplantation recipients. . PeerJ .2018 ;(6):e5864

25. 2018 Chien-Yu Huang,Po-Li Wei,Wei-Yu Chen,Wei-Chiao Chang,Yu-Jia Chang. Silencing Heat Shock Protein 27 Inhibits the Progression and Metastasis of Colorectal Cancer (CRC) by Maintaining the Stability of Stromal Interaction Molecule 1 (STIM1) Proteins. . Cells .2018 ;(7)

26. 2017 Wei-Chiao Chen,James Cheng-Chung Wei,Hsing-Fang Lu,Henry Sung-Ching Wong,Peng Yeong Woon,Yu-Wen Hsu,Jin-Ding Huang,Wei-Chiao Chang. rs657075 (CSF2) Is Associated with the Disease Phenotype (BAS-G) of Ankylosing Spondylitis. . International journal of molecular sciences .2017 ;(18)

27. 2017 Tsung-Chieh Yao,Su-Wei Chang,Wei-Chiao Chang,Ming-Han Tsai,Sui-Ling Liao,Man-Chin Hua, Shen-Hao Lai, Kuo-Wei Yeh, Yu-Lun Tseng, Wan-Chen Lin, Hui-Ju Tsai, Jing-Long Huang. Exposure to tobacco smoke and childhood rhinitis: a population-based study. . Scientific reports. .2017 ;(7):42836

28. 2017 Jhen-Hong Wong,Kuo-Hao Ho,Sean Nam,Wen-Li Hsu,Chia-Hsien Lin,Che-Mai Chang, Jaw-Yuan Wang, Wei-Chiao Chang. Store-operated Ca2+ Entry Facilitates the Lipopolysaccharide-induced Cyclooxygenase-2 Expression in Gastric Cancer Cells. . Scientific reports. .2017 ;(7):12813

29. 2017 Ho-Chang Kuo,Henry Sung-Ching Wong,Wei-Pin Chang,Ben-Kuen Chen,Mei-Shin Wu, Kuender D. Yang, Kai-Sheng Hsieh, Yu-Wen Hsu, Shih-Feng Liu, Xiao Liu, Wei-Chiao Chang. Prediction for Intravenous Immunoglobulin Resistance by Using Weighted Genetic Risk Score Identified From Genome-Wide Association Study in Kawasaki Disease. . Circulation. Cardiovascular genetics. .2017 ;(10): e001625

30. 2017 Wei-Chiao Chen, Wen-Chang Wang, Hsing-Fang Lu, Yukinori Okada,Wei-Pin Chang,Yii-Her Chou, Hui-Hua Chang, Jin-Ding Huang, Der-Yuan Chen, Wei-Chiao Chang. rs2841277 (PLD4) is associated with susceptibility and rs4672495 is associated with disease activity in rheumatoid arthritis. . Oncotarget .2017 ;(8):64180-64190

31. 2017 Chih-Chin Kao,Shih-Ying Cheng,Mei-Yi Wu,Shu-Chen Chien,Hsing-Fang Lu,Yu-Wen Hsu, Yan-Feng Zhang, Mai-Szu Wu, Wei-Chiao Chang. Associations of genetic variants of endothelin with cardiovascular complications in patients with renal failure. . BMC nephrology .2017 ;(18):291

32. 2017 Ying-Hsien Huang,Kuender D. Yang,Yu-Wen Hsu,Hsing-Fang Lu,Henry Sung-Ching Wong,Hong-Ren Yu, Hsing-Chun Kuo, Fu-Chen Huang, Mao-Hung Lo, Kai-Sheng Hsieh, Su-Fen Chen, Wei-Chiao Chang, Ho-Chang Kuo. Correlation of HAMP gene polymorphisms and expression with the susceptibility and length of hospital stays in Taiwanese children with Kawasaki disease. . Oncotarget .2017 ;(8):51859-51868

33. 2017 Henry Sung-Ching Wong,Che-Mai Chang,Chih-Chin Kao,Yu-Wen Hsu,Xiao Liu,Wen-Chang Chang, Mai-Szu Wu, Wei-Chiao Chang. V-J combinations of T-cell receptor predict responses to erythropoietin in end-stage renal disease patients. . Journal of biomedical science. .2017 ;(24):43

34. 2017 Sukhontip Klahan,Henry Sung-Ching Wong,Shih-Hsin Tu,Wan-Hsuan Chou,Yan-Feng Zhang,Thien-Fiew Ho, Chih-Yi Liu, Shih-Ying Yih, Hsing Fang Lu, Sean Chun-Chang Chen, Chi-Cheng Huang, Wei-Chiao Chang. Identification of genes and pathways related to lymphovascular invasion in breast cancer patients: A bioinformatics analysis of gene expression profiles. . Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. .2017 ;(39)

35. 2017 Ling-Sai Chang,Yu-Wen Hsu,Chien-Chang Lu,Mao-Hung Lo,Kai-Sheng Hsieh,Sung-Chou Li, Wei-Chiao Chang, Ho-Chang Kuo. CYP2E1 Gene Polymorphisms Related to the Formation of Coronary Artery Lesions in Kawasaki Disease. . The Pediatric infectious disease journal. .2017 ;(36):1039-1043

36. 2017 Kuo-Hao Ho,Peng-Hsu Chen,Edward Hsi,Chwen-Ming Shih, Wei-Chiao Chang,Chia-Hsiung Cheng, Cheng-Wei Lin, Ku-Chung Chen . Identification of IGF-1-enhanced cytokine expressions targeted by miR-181d in glioblastomas via an integrative miRNA/mRNA regulatory network analysis. . Scientific reports. .2017 ;(7):732

37. 2017 Huang YC,Chang WC,Huang YC,Lin CY,Wang CL,Dai CY, Ho CK, Wu MT, Chuang HY. Toxic Metals Increase Serum Tumor Necrosis Factor-α Levels, Modified by Essential Elements and Different Types of Tumor Necrosis Factor-α Promoter Single-nucleotide Polymorphisms. . Epidemiology. .2017 ;(28):S113-S120

38. 2016 Lin CH,Chung CA,Wong JH,Chen BK,Chiu SJ,Klahan S, Lee YC, Chang WC. Involvement of L-type Ca2+ channel and toll-like receptor-4 in nickel-induced interleukin-8 gene expression. . Environ Toxicol .2016 ;(1):5-12

39. 2016 Wong HSC,Chang CM,Xiao L,Huang WC,Chang WC. Characterization of cytokinome landscape for clinical responses in human cancers . oncoimmunology .2016 ;(0):e12147-e12147

40. 2016 Huang YH,Hsu YW,Lu HF,Wong HS,Yu HR,Kuo HC, Huang FC, Chang WC, Kuo HC.. Interferon-gamma Genetic Polymorphism and Expression in Kawasaki Disease. . Medicine (Baltimore) .2016 ;(95):e3501-e3501

41. 2015 Wang JY,Sun J,Huang MY,Wang YS,Hou MF,Sun Y, He H, Krishna N, Chiu SJ, Lin S, Yang S, Chang WC. STIM1 Overexpression Promotes Colorectal Cancer Progression, Cell Motility and COX-2 Expression . Oncogene .2015 ;(34):4358-67

42. 2015 Yang IH,Wong JH,Chang CM,Chen BK,Tsai YT,Chen WC, Wang ET, Hsu WL, Chang WC. Involvement of Intracellular Calcium Mobilization in IL-8 Activation in Human Retinal Pigment Epithelial Cells. . Invest Ophthalmol Vis Sci. .2015

43. 2015 Chang WC,Wu SL,Huang WC,Hsu JY,Chan SH,Wang JM, Tsai JP, Chen BK. PTX3 gene activation in EGF-induced head and neck cancer cell metastasis . Oncotarget .2015 ;([Epub):0-0

44. 2015 Juan YS,Lee YL,Long CY,Wong JH,Jang MY,u JH, Wu WJ, Huang YS, Chang WC*, Chuang SM*. Translocation of NF-κB and expression of cyclooxygenase-2 are enhanced by ketamine-induced ulcerative cystitis in rat bladder . Am J Pathol .2015 ;(185):2269-2285

45. 2015 Lou YT,Chen CW,Fan YC,Chang WC,Lu CY,Wu IC, Hsu WH, Huang CW, Wang JY. LINE-1 Methylation Status Correlates Significantly to Post-Therapeutic Recurrence in Stage III Colon Cancer Patients Receiving FOLFOX-4 Adjuvant Chemotherapy . PLoS One .2015 ;(10):e01239-e01239

46. 2015 Kuo HC,Hsu YW,Wu MS,Woon PY,Wong HS,Tsai LJ, Lin RK, Klahan S, Hsieh KS, Chang WC. FCGR2A Promoter Methylation and Risks for Intravenous Immunoglobulin Treatment Responses in Kawasaki Disease. . Mediators Inflamm .2015 ;(2015):564625-564625

47. 2015 Klahan S,Huang CC,Chien SC,Wu MS,Wong HS,Huang CY, Chang WC*, Wei PL*. Bioinformatic analyses revealed underlying biological functions correlated with oxaliplatin responsiveness . Tumour Biol .2015 ;(0):[Epub-[Epub

48. 2015 Lim LM,Zhao X,Chao MC,Chang JM,Chang WC,Kao HY, Hwang DY, Chen HC. Novel Vitamin D Receptor Mutations in Hereditary Vitamin D Resistant Rickets in Chinese . PLoS One .2015 ;(10):e01381-e01381

49. 2015 Wei JC,Sung-Ching HW,Hsu YW,Wen YF,Wang WC,Wong RH, Lu HF, Gaalen FA, Chang WC. Interaction between HLA-B60 and HLA-B27 as a Better Predictor of Ankylosing Spondylitis in a Taiwanese Population . PLoS One .2015 ;(10):e01371-e01371

50. 2015 Lu HF,Hung KS,Hsu YW,Tai YT,Huang LS,Wang YJ, Wong HS, Hsu YH, Chang WC. Association Study between the FTCDNL1 (FONG) and Susceptibility to Osteoporosis . PLoS One .2015 ;(10):e01405-e01405

51. 2015 Wong HS,Chang WC. Correlation of clinical features and genetic profiles of stromal interaction molecule 1 (STIM1) in colorectal cancers . Oncotarget .2015 ;(0):[Epub-[Epub

52. 2015 Wong HS,Juan YS,Wu MS,Zhang YF,Hsu YW,Che HH, Liu WM, Chang WC. Integrative bioinformatic analyses of an oncogenomic profile reveal the biology of endometrial cancer and guide drug discovery . Oncotarget .2015 ;(0):0-0

53. 2015 Sukhontip Klahan,Wan-Chen Huang,Che-Mai Chang,Henry SungChing Wong,Chi-Cheng Huang,Mei-Shin Wu, Yu-Chiao Lin, Hsing-Fang Lu, Ming-Feng Hou, Wei-Chiao Chang. Gene Expression Profiling Combined with Functional Analysis Identify Integrin Beta1 (ITGB1) as a Potential Prognosis Biomarker in Triple Negative Breast Cancer . Pharmacological Research .2015 ;(0):0-0

54. 2015 Lin YC,Wei PL,Tsai YT,Wong JH,Chang CM,Wang JY, Hou MF, Lee YC, Chuang HY, Chang WC. Pb2+ induced IL-8 gene expression by extracellular signal-regulated kinases and the transcription factor, activator protein 1, in human gastric carcinoma cells . Environ Toxicol .2015 ;(3):315-320

55. 2015 Chan CP,Tsai YT,Chen YL,Hsu YW,Tseng JT,Chuang HY, Shiurba R. Lee MH, Wang JY, Chang WC. Pb2+ induces gastrin gene expression by extracellular signal-regulated kinases 1/2 and transcription factor activator protein 1 in human gastric carcinoma cells. . Environ Toxicol .2015 ;(3):129-136

56. 2015 Tsai YT,Chang CM,Wang JY,Hou MF,Wang JM,Shiurba R, Chang WC, Chang WC. Function of DNA methyltransferase 3a in lead (Pb2+ )-Induced Cyclooxygenase-2 gene. . Environ Toxicol. .2015 ;(9):1024-1032

57. 2014 Chou PS,Chang WC,Chou WP,Liu ME,Lai CL,Liu CK, Ku YC, Tsai SJ, Chou YH, Chang WP. Increased risk of benign prostate hyperplasia in sleep apnea patients: a nationwide population-based study. . PLoS One. .2014 ;(9):e93081-e93081

58. 2014 Chang WC,Fang YY,Chang HW,Chuang LY,Lin YD,Hou MF, Yang CH. Identifying association model for single-nucleotide polymorphisms of ORAI1 gene for breast cancer. . Cancer Cell Int. .2014 ;(14):29-29

59. 2014 Wu PH,Lin YT,Kuo CN,Chang WC,Chang WP. No increased risk of herpes zoster found in cirrhotic patients: a nationwide population-based study in taiwan. . PLoS One. .2014 ;(9):e93443-e93443

60. 2014 Kuo HC,Wu CM,Chang WP,Kuo CN,Yeter D,Lin CY, Pai JT, Chi YC, Lin CH, Wang LJ, Chang WC. Association between Kawasaki Disease and Autism: A Population-Based Study in Taiwan. . Int J Environ Res Public Health. .2014 ;(11):3705-3716

61. 2014 Huang CH,Wei JC,Chang WC,Chiou SY,Chou CH,Lin YJ, Hung PH, Wong RH. Higher expression of whole blood microRNA-21 in patients with ankylosing spondylitis associated with programmed cell death 4 mRNA expression and collagen cross-linked C-telopeptide concentration. . J Rheumatol .2014 ;(41):1104-1111

62. 2014 Kan WC,Chou YH,Chiu SJ,Hsu YW,Lu HF,Hsu W, Chang WC. Study of the association between ITPKC genetic polymorphisms and calcium nephrolithiasis. . Biomed Res Int. .2014 ;(2014):397826-397826

63. 2014 Yen JH,Chang CM,Hsu YW,Lee CH,Wu MS,Hwang DY, Chen BK, Liao HT, Wu MT, Chang WC. A polymorphism of ORAI1 rs7135617, is associated with susceptibility to rheumatoid arthritis. . Mediators Inflamm .2014 ;(2014):834831-834831

64. 2014 Wang YJ,Hsu YW,Chang CM,Wu CC,Ou JC,Tsai YR, Chiu WT, Chang WC, Chiang YH, Chen KY. The influence of BMX gene polymorphisms on clinical symptoms after mild traumatic brain injury. . Biomed Res Int .2014 ;(2014):293687-293687

65. 2014 Shieh JM,Shen CJ,Chang WC,Cheng HC,Chan YY,Huang WC, Chang WC, Chen BK. An increase in reactive oxygen species by deregulation of ARNT enhances chemotherapeutic drug-induced cancer cell death. . PLoS One .2014 ;(9):e99242-e99242

66. 2014 Klahan S,Wu MS,Hsi E,Huang CC,Hou MF,Chang WC. Computational Analysis of mRNA Expression Profiles Identifies the ITG Family and PIK3R3 as Crucial Genes for Regulating Triple Negative Breast Cancer Cell Migration. . Biomed Res Int .2014 ;(2014):536591-536591

67. 2014 Chien SC,Chang WC,Lin PH,Chang WP,Hsu SC,Chang JC, Wu YC, Pei JK, Lin CH. A chinese herbal medicine, jia-wei-xiao-yao-san, prevents dimethylnitrosamine-induced hepatic fibrosis in rats. . ScientificWorldJournal. .2014 ;(2014):217525-217525

68. 2014 Chen PH,Shih CM,Chang WC,Cheng CH,Lin CW,Ho KH, Su PC, Chen KC. MicroRNA-302b-inhibited E2F3 transcription factor is related to all trans retinoic acid-induced glioma cell apoptosis. . J Neurochem .2014 ;(2014):0-0

69. 2014 Lin IL,Chou HL,Lee JC,Chen FW,Fong Y,Chang WC, Huang HW, Wu CY, Chang WT, Wang HM, Chiu CC. The antiproliferative effect of C2-ceramide on lung cancer cells through apoptosis by inhibiting Akt and NFκB. . Cancer Cell Int. .2014 ;(14):1-1

70. 2014 Chang WP,Liu ME,Chang WC,Yang AC,Ku YC,Pai JT, Lin YW, Tsai SJ. Sleep apnea and the subsequent risk of breast cancer in women: a nationwide population-based cohort study. . Sleep Med. .2014 ;(S1389-):00262-00267

71. 2014 Chou PS,Kuo CN,Hung KS,Chang WC,Liao YC,Chi YC, Chou WP, Tsai SJ, Liu ME, Lai CL, Chou YH, Chang WP. Osteoporosis and the Risk of Symptomatic Nephrolithiasis: A Population-Based 5-Year Follow-Up Study in Taiwan . Calcif Tissue Int .2014 ;(95):317-322

72. 2014 Tseng WN,Lo MH,Guo MM,Hsieh KS,Chang WC,Kuo HC. IL-31 Associated with Coronary Artery Lesion Formation in Kawasaki Disease . PLoS One .2014 ;(9):e10519-e10519

73. 2014 Chang WC. Pharmacogenomics in personalized medicine and drug metabolism . Biomed Res Int .2014 ;(2014):897963-897963

74. 2014 Kuo HC,Huang YH,Chien SC,Yu HR,Hsieh KS,Hsu YW, Chang WC. Genetic Variants of CD209 Associated with Kawasaki Disease Susceptibility . PLoS One .2014 ;(9):e10523-e10523

75. 2014 Wen YF,Wei JC,Hsu YW,Chiou HY,Wong HS,Wong RH, Ikegawa S, Chang WC. rs10865331 Associated with Susceptibility and Disease Severity of Ankylosing Spondylitis in a Taiwanese Population . PLoS One .2014 ;(9):e10452-e10452

76. 2014 Sun J,Lu F,He H,Shen J,Messina J,Mathew R, Wang D, Sarnaik AA, Chang WC, Kim M, Cheng H, Yang S. STIM1- and Orai1-mediated Ca2+ oscillation orchestrates invadopodium formation and melanoma invasion . J Cell Biol .2014

77. 2014 Klahan S,Kuo CN,Chien SC,Lin YW,Lin CY,Lin CH, Chang WC, Lin CI, Hung KS, Chang WP. Osteoporosis increases subsequent risk of gallstone: a nationwide population-based cohort study in Taiwan . BMC Gastroenterol .2014 ;(14):192-192

78. 2014 Lin CH,Chang WC,Kuo CN,Yu HC,Yang CC,Lin YW, Hung KS, Chang WP. A population-based five-year study on the risk of stroke in patients with osteoporosis in Taiwan . Bone .2014

79. 2014 Chang WP,Huang JJ,Klahan S,Su PF,Kuo CN,Yu HC, Chang WC, Huang MY. Association between oral cavity cancer and depression: A population-based study in Taiwan. . Oral Oncol. .2014 ;(50):e21-e22

80. 2014 Kuo HC,Hsu YW,Lo MH,Huang YH,Chien SC,Chang WC. Single-Nucleotide Polymorphism rs7251246 in ITPKC Is Associated with Susceptibility and Coronary Artery Lesions in Kawasaki Disease. . PLoS One. .2014 ;(9):e91118-e91118

81. 2013 Kuo HC,Hsu YW,Wu CM,Chen HY,Hung KS,Chang WP, Yang KD, Hsoeh KS, Chen WC, Onouchi Y and Chang WC. A Replication Study for Association of ITPKC and CASP3 Two-locus analysis in IVIG unresponsiveness and coronary artery lesion in Kawasaki disease . PLoS One .2013 ;(8):e69685

82. 2013 Lee HY,Li JH,Sheu YL,Tang HP,Chang WC,Tang TC, Yeh YC, Wang SY, Liu RH. Moving toward personalized medicine in the methadone maintenance treatment program: a pilot study on the evaluation of treatment responses in Taiwan. . Biomed Res Int. .2013

83. 2013 Chang WP,Liu ME,Chang WC,Yang AC,Ku YC,Pai JT, Huang HL, Tsai SJ. Sleep apnea and the risk of dementia: a population-based 5-year follow-up study in Taiwan. . PLoS One. .2013 ;(8):e78655-e78655

84. 2013 Chang WC,Yang KD,Wu MT,Wen YF,Hsi E,Chang JC, Lin YM, Kuo HC, Chang WP. Close correlation between season of birth and the prevalence of bronchial asthma in a Taiwanese population. . PLoS One. .2013 ;(8):e80285-e80285

85. 2013 Chang WP,Wu SJ,Chang WC,Kuo HC. Population-based study of the association between Urbanization and Kawasaki Disease in Taiwan . The scientific world journal .2013 ;(2013)

86. 2013 Woon PY,Chang WC,Liang CC,Hsu CH,Klahan S,Huang YH, Chang WP, Kuo HC. Increased risk of atopic dermatitis in preschool children with kawasaki disease: a population-based study in taiwan . Evid Based Complement Alternat Med .2013

87. 2013 Chang WP,Chang WC,Wu MS,Pai JT,Guo YC,Chen KC, Liu ME, Chiu WT, Hung KS. Population-based 5-year Follow-up Study in Taiwan of Osteoporosis and Risk of Periodontitis . J Periodontol .2013

88. 2013 Chang WC,Yang KD,Wu MTM,Wen YF,Chang YM,Kuo HC, Chang WP. Close Correlation between Season of Birth and the Prevalence of Bronchial Asthma in a Taiwanese Population . PLoS One .2013

89. 2013 Wei JC,Hsu YW,Hung KS,Wong RH,Huang CH,Liu YT, Guo YC, Ikegawa S, Chang WC. Association study of polymorphisms rs4552569 and rs17095830 and the risk of ankylosing spondylitis in a Taiwanese population . PLoS One .2013

90. 2013 Guo YC,Chang CM,Hsu WL,Chiu SJ,Tsai YT,Chou YH, Hou MF, Wang JY, Lee MH, Tsai KL, Chang WC. Indomethacin inhibits cancer cell migration via attenuation of cellular calcium mobilization . Molecules .2013

91. 2013 Chan CP,Tsai YT,Chen YL,Hsu YW,Tseng JT,Chuang HY, Shiurba R, Lee MH, Wang JY, Chang WC. Pb2+ induces gastrin gene expression by extracellular signal-regulated kinases 1/2 and transcription factor activator protein 1 in human gastric carcinoma cells. . Environ Toxicol .2013

92. 2013 Hsu YW,Chuen SC,Liang CC,Yang KD,Chang WP,Lee JA, Kuo HC, Chang WC. Stromal Interaction Molecule 1 Polymorphisms are Associated with Coronary Artery Dilation but not with Aneurysm Formation in Patients with Kawasaki Disease . J Exp Clin Med .2013

93. 2013 Chang WP,Liu ME,Chang WC,Yang AC,Ku YC,Pai JT, Huang HL, Tsai SJ. Sleep Apnea and the Risk of Dementia: A Population-Based 5-Year Follow-Up Study in Taiwan . PLoS One .2013 ;(8):e78655

94. 2013 Lim LM,Chang JM,Wang IF,Chang WC,Hwang DY,Chen HC. Atypical X-linked agammaglobulinaemia caused by a novel BTK mutation in a selective immunoglobulin M deficiency patient. . BMC Pediatr .2013 ;(13):150-150

95. 2013 Hsu WL,Chiu SJ,Tsai YT,Chang CM,Wang JY,Wang ET, Hou MF, Huang CY, Sheu JH, Chang WC. A Soft Coral Natural Product, 11-Episinulariolide Acetate, Inhibits Gene Expression of Cyclooxygenase-2 and Interleukin-8 through Attenuation of Calcium Signaling. . Molecules .2013 ;(18):7024-7034

96. 2013 Yang IH,Tsai YT,Chiu SJ,Liu LT,Lee HH,Hou MF, Hsu WL, Chen BK, Chang WC.. Involvement of STIM1 and Orai1 in EGF-mediated cell growth in retinal pigment epithelial cells. . J Biomed Sci. 2013 Jun 25;20(1):41. .2013 ;(20):41

97. 2013 Liu ME,Tsai SJ,Chang WC,Hsu CH,Lu T,Hung HS, Chiu WT, Chang WP. Population-based 5-year Follow-up Study in Taiwan of Dementia and Risk of Stroke . PLoS One .2013 ;(8):e61771-e61771

98. 2013 Kuo HC,Chang WC,Yang KD,Yu HR,Wang CL,Ho SC, Yang CY. Kawasaki disease and subsequent risk of allergic diseases: a population-based matched cohort study . BMC Pediatr .2013

99. 2013 Chuang SM,Liu KM,Lee YC,Chang CY,Wu WJ,Chang WC, Robert M. Levin, Juan YS. Effects of supraphysiological testosterone treatment and orchiectomy on ischemia/reperfusion-induced bladder dysfunction in male rabbit . J Sex Med .2013

100. 2013 Chuang SM,Liu KM,Li YL,Jang MY,Lee HH,Wu WJ, Chang WC, Robert M Levins, Juan YS. Dual involvements of cyclooxygenase and nitric oxide synthase expressions in ketamine-induced ulcerative cystitis in rat bladder . Neurourol Urodyn .2013

101. 2013 Wei JC,Hsu YW,Hung KS,Wong RH,Huang CH,Liu YT, Guo YC, Ikegawa S, Chang WC. Association study of polymorphisms rs4552569 and rs17095830 and the risk of ankylosing spondylitis in a Taiwanese population . PLoS One .2013 ;(8):e52801-e52801

102. 2013 Chuang SM,Long CY,Lin RJ,Liu KM,Levin RM,Chang CY, Ho YW, Wu WJ, Chang WC, Juan YS. Protective effects of estrogen on ischemia/reperfusion–induced bladder dysfunction in female rabbits . Menopause .2013 ;(20):209-217

103. 2012 Chen CJ,Huang FC,Tiao MM,Huang YH,Lin LY,Yu HR, Yang KD, Huang YC, Chen CC, Chang WC, Kuo HC. Sonographic Gallbladder Abnormality Is Associated with . ScientificWorldJournal .2012 ;(2012):485758-485758

104. 2012 Chou YH,Chang WC,Wu WJ,Li CC,Yeh HC,Chou PS, Lee MH, Chang WP, Li WM. The association between gender and outcome of patients with upper tract urothelial cancer . The Kaohsiung journal of medical sciences .2012 ;(29):37-42

105. 2012 Lin YJ,Lin IC,Yu HR,Kuo HC,Yang KD,Chang WC, Liang CD, Liu SF, Kuo HC. Tricuspid regurgitation in acute phase of kawasaki disease associated with intensive care unit admission . Pediatr Cardiol .2012 ;(34):250-255

106. 2012 Wei CC,Hung KS,Hsu YW,Wong RH,Huang CH,Jan MS, Wu SJ, Juan YS, Chang WC. Genetic Polymorphisms of Stromal Interaction Molecule 1 Associated with the Erythrocyte Sedimentation Rate and C-Reactive Protein in HLA-B27 Positive Ankylosing Spondylitis Patients . PloS one .2012 ;(7):e49698-e49698

107. 2012 Chang WC,Lee CH,Hirota T,Wang LF,Doi S,Miyatake A, Enomoto T, Tomita K, Sakashita M, Yamada T, Fujieda S, Ebe K, Saeki H, Takeuchi S et al.. ORAI1 genetic polymorphisms associated with the susceptibility of atopic dermatitis in Japanese and Taiwanese populations . PLoS One .2012 ;(7):e29387-e29387

108. 2012 Chang WP,Yang YL,Hsu YW,Chen WC,Yu HR,Liang CD, Tsai YT, Huang YH, Yang KD, Kuo HC, Chang WC. Lack of association between CLEC5A gene single nucleotide polymorphisms and Kawasaki disease in Taiwanese children . J Biomed Biotechnol .2012 ;(2012:)

109. 2012 Kuo HC,Chao MC,Hsu YW,Lin YC,Huang YH,u HR, Hou MF, Liang CD, Yang KD, Wang CL, Chang WC. CD40 Gene polymorphisms associated with susceptibility and coronary artery lesions of Kawasaki disease in the Taiwanese population . ScientificWorldJournal .2012 ;(2012)

110. 2012 Chang WC,Woon PY,Wei CC,Chang CM,Hsu YW,Guo YC, Hwang DY, Kochi Y, Yen JH. A single-nucleotide polymorphism of CCR6 (rs3093024) is associated with susceptibility to rheumatoid arthritis but not ankylosing spondylitis, in a Taiwanese population . J Rheumatol .2012 ;(39):1765

111. 2012 Chang WC. Genetic Variants of Store-Operated Channels and Human Diseases . J Cell Sci Ther .2012 ;(3):1000e1

112. 2012 Kuo HC,Chang WC. The Genomics and Pharmacogenomics of Kawasaki Disease . J Cell Sci Ther .2012 ;(3):1000e1

113. 2012 Kuo HC,Yang YL,Chuang JH,Tiao MM,Yu HR,Huang LT, Yang KD, Chang WC, Lee CP, Huang YH. Inflammation-Induced Hepcidin is Associated with the Development of Anemia and Coronary Artery Lesions in Kawasaki Disease . J Clin Immunol .2012 ;(2012):746-752

114. 2012 Hong CH,Yu HS,Ko YC,Chang WC,Chuang HY,Chen GS, Lee CH. Functional regulation of interleukin-31 production by its genetic polymorphism in patients with extrinsic atopic dermatitis . Acta Derm Venereol. .2012 ;(92):430-432

115. 2012 Chang WC,Woon PY,Hsu YW,Yang S,Chiu YC,Hou MF. The association between single-nucleotide polymorphisms of ORAI1 gene and breast cancer in a Taiwanese population . ScientificWorldJournal .2012 ;(2012)

116. 2012 Yu HR,Chang WP,Wang L,Lin YJ,Liang CD,Yang KD, Kuo CM, Huang YC, Chang WC, Kuo HC. DC-SIGN (CD209) promoter -336 A/G (rs4804803) polymorphism associated with susceptibility of Kawasaki disease . ScientificWorldJournal .2012 ;(2012)

117. 2012 Liu CS,Chang CC,Du YC,Chang FR,Wu YC,Chang WC, Hsieh TJ. 2-hydroxy-4'-methoxychalcone inhibits proliferation and inflammation of human aortic smooth muscle cells by increasing the expression of peroxisome proliferator-activated receptor gamm . J Cardiovasc Pharmacol. .2012 ;(59)

118. 2012 Wu TY,Yang IH,Tsai YT,Wang JY,Shiurba R,Hsieh TJ, Chang FR, Chang WC. Isodesacetyluvaricin, an Annonaceous acetogenin, specifically inhibits gene expression of cyclooxygenase-2 . J Nat Prod .2012 ;(2012):572-576

119. 2012 Lin YL,Yang TH,Liang CD,Yu HR,Yang KD,Huang YC, Chang WC, Kuo HC. Comparison of the laboratory data between Kawasaki disease and enterovirus after intravenous immunoglobulin treatment . Pediatr Cardiol .2012 ;(2012):1269-1274

120. 2012 Chang WC,Liao CY,Chen WC,Fan YC,Chiu SJ,Kuo HC, Woon PY, Chao MC. R450H TSH receptor mutation in congenital hypothyroidism in Taiwanese children . Clin Chim Acta .2012 ;(413):1004-1007

121. 2012 Kuo HC,Yang KD,Chang WC,Ger LP,Hsieh KS. Kawasaki disease: an update on diagnosis and treatment . Pediatr Neonatol .2012 ;(53):4-11

122. 2012 Wang JY,Chen BK,Wang YS,Tsai YT,Chen WC,Chang WC, Hou MF, Wu YC, Chang WC. Involvement of store-operated calcium signaling in EGF-mediated COX-2 gene activation in cancer cells . Cell Signal .2012 ;(20):41

123. 2012 Chen CJ,Huang FC,Tiao MM,Huang YH,Lin LY,Yu HR, Yang KD, Huang YC, Chen CC, Chang WC, Kuo HC. Sonographic Gallbladder Abnormality Is Associated with intravenous immunoglobulin resistance in Kawasaki disease. . ScientificWorldJournal .2012 ;(2012)

124. 2012 Juan YS,Chuang SM,Lee YL,Long CY,Wu TH,Chang WC, Levin RM, Liu KM, Huang CH.. Green tea catechins decrease oxidative stress in surgical menopause-induced overactive bladder in a rat model . BJU Int .2012 ;(110):E236-E244

125. 2011 Kuo HC,Onouchi Y,Hsu YW,Chen WC,Huang JD,Huang YH, Yang YL, Chao MC, Yu HR Juan YS, Kuo CM, Yang KD, Huang JS, Chang WC. Polymorphisms of Transforming Growth Factor-β Signaling Pathway and Kawasaki Disease in the Taiwanese population . Journal of Human Genetics .2011 ;(56):840-845

126. 2011 Kuo HC,Yu HR,Juo SH,Yang KD,Wang YS,Liang LD, Chen WC, Chang WP, Huang CF, Lee CP, Lin LY, Liu YC, Guo YC, Chiu CC, Chang WC. CASP3 gene single nucleotide polymorphism (rs72689236) and Kawasaki disease in Taiwanese children . J Hum Genet .2011 ;(56):161-165

127. 2011 Chou YH,Juo SH,Chiu YC,Liu ME,Chen WC,Chang CC, Chang WP, Chang JG, Chang WC. A Polymorphism of ORAI1 Gene is Associated with the Risk and Recurrence of Calcium Nephrolithiasis . J Urology .2011 ;(185):1742-1746

128. 2011 Huang WC,Chai CY,Chen WC,Hou MF,Wang YS,Chiu YC, Lu SR, Chang WC, Juo SH, Wang JY, Chang WC. Histamine regulates Cycloxygenase 2 gene activation through Orai1-mediated NFκB activation in lung cancer cells . Cell Calcium .2011 ;(50):27-35

129. 2011 Kuo HC,Chang WC. Genetic polymorphisms of Kawasaki disease . Acta Pharmacologica Sinica .2011 ;(2011):1193-1198

130. 2011 Chou YH,Li CC,Hsu H,Chang WC,Liu CC,Li WM, Ke ML, Lee MH, Liu ME, Pan SH, Wang HS. Renal function in patients with urinary stones of varying compositions . Kaohsiung J Med Sci .2011 ;(27):264-267

131. 2011 Chen KC,Wang YS,Hu CY,Chang WC,Liao YC,Dai CY, Juo SH. OxLDL up-regulates microRNA-29b, leading to epigenetic modifications of MMP-2/MMP-9 genes: a novel mechanism for cardiovascular diseases . FASEB J .2011 ;(25):1718-1728

132. 2011 Sun J,He H,Xiong Y,Lu S,Shen J,Cheng A, Chang WC, Hou MF, Lancaster JM, Kim M, Yang S. Fascin is critical for transforming growth factor {beta} induced invasion and filopodia formation in spindle-shaped tumor cells . J Biol Chem .2011 ;(286):38865-38875

133. 2011 Hsieh TJ,Hsieh PC,Wu MT,Chang WC,Hsiao PJ,Lin KD, Chou PC, Shin SJ. Betel nut extract and arecoline block insulin signaling and lipid storage in 3T3-L1 adipocytes . Cell Biol Toxicol .2011

134. 2011 Chou YH,Woon PY,Chen WC,Hsu YW,Chang JM,Hwang DY, Chiu YC, Kuo HC, Chang WP, Hou MF, Liu ME, Chang JG, Chang WC. A genetic polymorphism (rs17251221) in the calcium-sensing receptor gene (CASR) is associated with stone multiplicity in calcium nephrolithiasis . PLoS One .2011 ;(6):e25227

135. 2011 Kuo HC,Lin YJ,Juo SH,Hsu YW,Chen WC,Yang KD, Liang CD, Yang S, Chao MC, Yu HR, Wang S, Lin LY, Chang WC. Lack of Association between ORAI1/CRACM1 Gene Polymorphisms and Kawasaki Disease in Taiwanese Children . J Clin Immunol .2011 ;(31):650-655

136. 2011 Kuo HC,Yang KD,Juo SH,Liang CD,Chen WC,Wang YS, Lee CH, Hsi E, Yu HR, Woon PY, Lin IC, Huang CF, Hwang DY, Lee CP, Lin LY, Chang WP, Ch. ITPKC single nucleotide polymorphism associated with the Kawasaki disease in a Taiwanese population . PLoS One .2011 ;(6):e17370

137. 2011 Chou YH,Woon PY,Huang WC,Shiurba R,Tsai YT,Wang YS, Hsieh TJ, Chang WC, Chuang HY , Chang WC. Divalent lead cations induce cyclooxygenase-2 gene expression by epidermal growth factor receptor/nuclear factor-kappa B signaling in A431carcinoma cells . Toxicol Lett .2011 ;(203):147-153

138. 2011 Wei CC,Yen JH,Juo SH,Chen WC,Wang YS,Chiu YC, Hsieh TJ, Guo YC, Wong RH, Huang CH, Wang HP, Tsai KL, Wu YC, Chang HW, Hsi E, Chang WP, C. Association of ORAI1 haplotypes with the risk of HLA-B27 positive ankylosing spondylitis . PLoS One .2011 ;(6):e20426

139. 2011 Chang WC,Chang CC,Wang YS,Wang YS,Weng WT,Yoshioka T, Juo SH. Involvement of the epidermal growth factor receptor in Pb(2+)-induced activation of cPLA(2)/COX-2 genes and PGE(2) production in vascular smooth muscle cells . Toxicology .2011 ;(279):45-53

140. 2011 Hou MF,Kuo HC,Li JH,Wang YS,Chang CC,Chen KC, Chen WC, Chiu CC, Yang S, Chang WC. Orai1/CRACM1 Overexpression Suppresses Cell Proliferation via Attenuation of the Store-Operated Calcium Influx-mediated Signalling Pathway in A549 Lung Cancer Cells . Biochimica et Biophysica Acta .2011 ;(1810):1278-1284

141. 2010 Kuo HC,Liang CD,Yu HR,Wang CL,Lin IC,Liu CA, Chang JC, Lee CP, Chang WC, Yang KD.. CTLA-4, Position 49 A/G Polymorphism Associated with Coronary Artery Lesions in Kawasaki Disease . J Clin Immunol .2010 ;(67):3523-3533

142. 2010 Huang WC,Chen ST,Chang WC,Chang KY,Chang WC,Chen BK. Involvement of aryl hydrocarbon receptor nuclear translocator in EGF-induced c-Jun/Sp1-mediated gene expression . Cell Mol Life Sci .2010 ;(67):3523-3533

143. 2008 Chang WC,di Capite JL,Singaravelu k,Nelson C,Halse V,Parekh AB. Local Ca2+ influx through CRAC channels stimulates production of an intracellular messenger and an intercellular pro-inflammatory signal . Journal of biological chemistry .2008 ;(283):4622-4631