Specialty
Epidemiology, Applied Biostatistics, Data Analysis, Molecular Epidemiology, Association studies, Public Health
Research Description
To evaluate the frequency of human diseases and health events, particularly in the field of breast cancer, colorectal cancer and susceptibility. Furthermore, to discuss the gene-environment interactions in breast and colorectal cancer. Otherwise, the military medicine for health surveillance of soldiers and applied biostatistics in clinical medicine are also my interests.
Selected Publications: (2018-2020)
1. Tzeng NS, Chung CH, Lin FH, Huang CF, Yeh CB, Huang SY, Lu RB, Chang HA, Kao YC, Yeh HW, Chiang WS, Chou YC, Tsao CH, Wu YF, Chien WC. Magnesium oxide use and reduced risk of dementia: a retrospective, nationwide cohort study in Taiwan. Curr Med Res Opin 2018 Jan;34(1):163-169. (2017 JCR SCI, IF= 2.665, 36/154=23.4%, Medicine, General & Internal)
2. Tseng MH, Lin SH, Wu CY, Chien HP, Yang HY, Chen YC, Chou YC, Huang JL. Serum complement factor I is associated with disease activity of systemic lupus erythematosus. Oncotarget 2018 Jan 3;9(9):8502-8511. (2017 Non-SCI)
3. Chen YH, Kuo TT, Yi-Kung Huang E, Hoffer BJ, Chou YC, Chiang YH, Ma HI, Miller JP. Profound deficits in hippocampal synaptic plasticity after traumatic brain injury and seizure is ameliorated by prophylactic levetiracetam. Oncotarget 2018 Jan 4;9(14):11515-11527. (2017 Non-SCI)
4. Chen YH, Kuo TT, Yi-Kung Huang E, Chou YC, Chiang YH, Hoffer BJ, Miller J. Effect of traumatic brain injury on nicotine-induced modulation of dopamine release in the striatum and nucleus accumbens shell. Oncotarget 2018 Jan 13;9(11):10016-10028. (2017 Non-SCI)
5. Tzeng NS, Chung CH, Liu FC, Chiu YH, Chang HA, Yeh CB, Huang SY, Lu RB, Yeh HW, Kao YC, Chiang WS, Tsao CH, Wu YF, Chou YC, Lin FH, Chien WC. Fibromyalgia and Risk of Dementia-A Nationwide, Population-Based, Cohort Study. Am J Med Sci 2018 Feb;355(2):153-161. (2017 JCR SCI, IF= 1.773, 68/154=44.2%, Medicine, General & Internal)
6. Chen YH, Kuo TT, Kao JH, Huang EY, Hsieh TH, Chou YC, Hoffer BJ. Exercise Ameliorates Motor Deficits and Improves Dopaminergic Functions in the Rat Hemi-Parkinson's Model. Sci Rep 2018 Mar 5;8(1):3973. (2017 JCR SCI, IF= 4.122, 12/64=18.8%, Multidisciplinary sciences)
7. Chao PC, Chien WC, Chung CH, Chu CW, Yeh CB, Huang SY, Lu RB, Chang HA, Kao YC, Yeh HW, Chiang WS, Chou YC, Tzeng NS*. Cognitive enhancers associated with decreased risk of injury in patients with dementia: a nationwide cohort study in Taiwan. J Investig Med 2018 Mar;66(3):684-692. (2017 JCR SCI, IF= 2.029, 55/154=35.7%, Medicine, General & Internal)
8. Hu JM, Shen CJ, Chou YC, Hung CF, Tian YF, You SL, Chen CY, Hsu CH, Hsiao CW, Lin CY,Sun CA*. Risk of colorectal cancer in patients with periodontal disease severity: a nationwide, population-based cohort study. Int J Colorectal Dis 2018 Mar;33(3):349-352. (2017 JCR SCI, IF=2.533, 57/80=71.3% in Gastroenterology & Hepatology; 61/200=30.5% in Surgery)
9. Wang HY, Chen JH, Huang SY, Yeh HW, Mao WC, Chang HA, Kao YC, Yeh CB, Chou YC, Chiang WS, Tzeng NS*. Forensic Evaluations for Offenders With Dementia in Taiwan's Criminal Courts. J Am Acad Psychiatry Law 2018 Mar;46(1):45-51. (2017 JCR SSCI, IF=1.231, 51/150=34% in Law; 98/142=69% in Psychiatry)
10.Wu WC, Hsieh PC, Hu FK, Kuan JC, Chu CM, Sun CA, Yang T, Su SL, Chou YC*. Long-term predictive models of risk factors for early chronic kidney disease: a longitudinal study. Oncotarget 2018 Apr 13; 9(28):19745-19752. (2016 JCR SCI, IF= 5.168, 44/217=20.3%, Oncology) (2017 Non-SCI) (Corresponding author)
11.Tzeng NS, Chung CH, Lin FH, Chiang CP, Yeh CB, Huang SY, Lu RB, Chang HA, Kao YC, Yeh HW, Chiang WS, Chou YC, Tsao CH, Wu YF, Chien WC. Anti-herpetic Medications and Reduced Risk of Dementia in Patients with Herpes Simplex Virus Infections-a Nationwide, Population-Based Cohort Study in Taiwan. Neurotherapeutics 2018 Apr;15(2):417-429. (2017 JCR SCI, IF=5.719, 34/261=13.1%, Neurosciences)
12.Tzeng NS, Chang HA, Chung CH, Kao YC, Chang CC, Yeh HW, Chiang WS, Chou YC, Chang SY, Chien WC. Increased Risk of Psychiatric Disorders in Allergic Diseases: A Nationwide, Population-Based, Cohort Study. Front Psychiatry 2018 Apr 24;9:133. (2017 JCR SCI, IF=2.857, 60/142=42.3%, Psychiatry)
13.Chang SY, Kuo CC, Wu CC, Hsiao CW, Hu JM, Hsu CH, Chou YC, Shih YL, Lin YW. NKX6.1 hypermethylation predicts the outcome of stage II colorectal cancer patients undergoing chemotherapy. Genes Chromosomes Cancer 2018 May;57(5):268-277. (2017 JCR SCI, IF= 3.362, 102/223=45.7%, Oncology)
14.Tang MB, Huang WT, Wu WC, Chang HF, Lin YW, Lin MH, Lin YL, Chang HW, Chou YC*, Yu CP*. Detection of rotavirus and adenovirus in elderly patients with and without acute gastroenteritis in Taiwan. Southeast Asian J Trop Med Public Health 2018 Jul; 49(4): 639-645. (2017 JCR SCI, IF= 0.817, 164/180=92%, Public, Environmental & Occupational Health) (Corresponding author)
15.Lin JC, Tsai JT, Chou YC, Li MH, Liu WH. Compared with intensity-modulated radiotherapy, image-guided radiotherapy reduces severity of acute radiation-induced skin toxicity during radiotherapy in patients with breast cancer. Cancer Med 2018 Aug;7(8):3622-3629. (2017 JCR SCI, IF= 3.202, 111/223=49.8%, Oncology)
16.Wu HF, Kao LT, Shih JH, Kao HH, Chou YC, Li IH, Kao S. Pioglitazone use and Parkinson's disease: a retrospective cohort study in Taiwan. BMJ Open 2018 Aug 29;8(8):e023302. (2017 JCR SCI, IF= 2.413, 43/154=27.9%, Medicine, General & Internal)
17.Chen YH, Kuo TT, Huang EY, Hoffer BJ, Kao JH, Chou YC, Chiang YH, Miller J. Nicotine-Induced Conditional Place Preference Is Affected by Head Injury: Correlation with Dopamine Release in the Nucleus Accumbens Shell. Int J Neuropsychopharmacol 2018 Oct 1;21(10):949-961. (2017 JCR SCI, IF=3.981, 74/261=28.4%, Neurosciences)
18.Chang SY, Chien WC, Chung CH, Chang HA, Kao YC, Yeh HW, Chou YC, Peng CK, Shen CH, Tzeng NS. Risk of dementia after charcoal-burning suicide attempts: a nationwide cohort study in Taiwan. J Investig Med 2018 Oct;66(7):1070-1082. (2017 JCR SCI, IF= 2.029, 55/154=35.7%, Medicine, General & Internal)
19.Huang HH, Wang YC, Chou YC, Yu MH, Chao TK. The combination of aldehyde dehydrogenase 1 (ALDH1) and CD44 is associated with poor outcomes in endometrial cancer. PLoS One 2018 Oct 29;13(10):e0206685. (2017 JCR SCI, IF= 2.766, 15/64=23.4%, Multidisciplinary sciences)
20.Hsieh YH, Weng TH, Chou YC, Wu KL, Liang CM, Tai MC. Agreement of post-LASIK corneal power and corneal thickness measurements by pentacam and GALILEI corneal tomography systems. J Chin Med Assoc 2019 Jan;82(1):72-77. (2018 JCR SCI, IF= 1.894, 67/160=42%, Medicine, General & Internal)
21.Tseng YC, Chen BC, Chen CT, Chou YC, Dai NT, Chen PJ, Huang TY, Shih YL, Chang WK, Hsieh TY, Lin JC. Early Initiation of Post-Pyloric Feeding in Patients with Major Burns: Experience in Taiwan Formosa Water Park Dust Explosion Disaster. Tohoku J Exp Med. 2019 Feb;247(2):111-118. (2018 JCR SCI, IF= 1.584, 80/160=50%, Medicine, General & Internal)
22.Hu CC, Chang TH, Chou YC, Hsu HH. Significance and positive predictive values of mammographic findings in the Asia-Pacific region: a single-centre study in Taiwan. Clin Radiol 2019 Feb;74(2):166.e1-166.e7. (2018 JCR SCI, IF= 2.082, 67/129=52%, Radiology, Nuclear Medicine & Medical Imaging)
23.Hung CC, Li YT, Chou YC, Chen JE, Wu CC, Shen HC, Yeh TT. Conventional plate fixation method versus pre-operative virtual simulation and three-dimensional printing-assisted contoured plate fixation method in the treatment of anterior pelvic ring fracture. Int Orthop 2019 Feb;43(2):425-431. (2018 JCR SCI, IF= 2.384, 27/76=36%, Orthopedics)
24.Li YT, Hung CC, Chou YC, Chen JE, Wu CC, Shen HC, Yeh TT. Surgical Treatment for Posterior Dislocation of Hip Combined with Acetabular Fractures Using Preoperative Virtual Simulation and Three-Dimensional Printing Model-Assisted Precontoured Plate Fixation Techniques. Biomed Res Int 2019 Feb 28;2019:3971571. (2018 JCR SCI, IF= 2.197, 83/136=62%, Medicine, Research & Experimental)
25.Chen YH, Lin BJ, Hsieh TH, Kuo TT, Miller J, Chou YC, Huang EY, Hoffer BJ. Differences in Nicotine Encoding Dopamine Release between the Striatum and Shell Portion of the Nucleus Accumbens. Cell Transplant 2019 Mar;28(3):248-261. (2018 JCR SCI, IF= 3.477, 54/136=39.8% in Medicine, Research & Experimental; 10/25=40% in Transplantation)
26.Kao HH, Kao LT, Li IH, Pan KT, Shih JH, Chou YC*, Wu ST. Androgen Deprivation Therapy Use Increases the Risk of Heart Failure in Patients With Prostate Cancer: A Population-Based Cohort Study. J Clin Pharmacol 2019 Mar;59(3):335-343. (2018 JCR SCI, IF= 2.915, 110/267=41.2%, Pharmacology & Pharmacy) (Corresponding author)
27.Tsai YT, Hsu CL, Hung CC, Chou YC, Wu CC, Yeh TT. Conventional plate fixation versus minimally invasive modified pedicle screw-rod fixation for anterior pelvic ring fractures. PLoS One 2019 Apr 8;14(4):e0215233. doi: 10.1371/journal.pone.0215233. (2018 JCR SCI, IF= 2.776, 24/69=34.8%, Multidisciplinary sciences)
28.Chiu YL, Chou YC, Chang YW, Chu CM, Lin FG, Lai CH, Hwang SL, Fang WH, Kao S. Using an extended theory of planned behaviour to predict smoking cessation counsellors' intentions to offer smoking cessation support in the Taiwanese military: a cross-sectional study. BMJ Open 2019 May 9;9(5):e026203. doi: 10.1136/bmjopen-2018-026203. (2018 JCR SCI, IF= 2.376, 50/160=31.3%, Medicine, General & Internal)
29.Tsai YY, Chen BC, Chou YC, Lin JC, Lin HH, Huang HH, Huang TY. Clinical characteristics and risk factors of active bleeding in colonic angiodysplasia among the Taiwanese. J Formos Med Assoc 2019 May;118(5):876-882. (2018 JCR SCI, IF= 2.844, 35/160=22%, Medicine, General & Internal)
30.Li YC, Chou YC, Chen HC, Lu CC, Chang DM. Interleukin-6 and interleukin-17 are related to depression in patients with rheumatoid arthritis. Int J Rheum Dis 2019 Jun;22(6):980-985. (2018 JCR SCI, IF=1.938, 24/31=78%, Rheumatology)
31.Chen YH, Hsieh TH, Kuo TT, Kao JH, Ma KH, Huang EY, Chou YC, Olson L, Hoffer BJ. Release parameters during progressive degeneration of dopamine neurons in a mouse model reveal earlier impairment of spontaneous than forced behaviors. J Neurochem 2019 Jul;150(1):56–73. doi:10.1111/jnc.14702 (2018 JCR SCI, IF= 4.870, 53/267=19.9%, Neurosciences)
32. Tzeng NS, Chung CH, Lin FH, Yeh CB, Huang SY, Lu RB, Chang HA, Kao YC, Yeh HW, Chiang WS, Chou YC, Tsao CH, Wu YF, Chien WC. Risk of Dementia in Adults With ADHD: A Nationwide, Population-Based Cohort Study in Taiwan. J Atten Disord 2019 Jul;23(9):995-1006. doi: 10.1177/1087054717714057. (2018 JCR SCI, IF= 3.656, 43/146=29.5%, Psychiatry)
33.Hsu CL, Chou YC, Li YT, Chen JE, Hung CC, Wu CC, Shen HC, Yeh TT. Pre-operative virtual simulation and three-dimensional printing techniques for the surgical management of acetabular fractures. Int Orthop 2019 Aug;43(8):1969–1976. doi:10.1007/s00264-018-4111-8 (2018 JCR SCI, IF= 2.384, 27/76=35.6%, Orthopedics)
34.Chung HH, Kuo CC, Hsiao CW, Chen CY, Hu JM, Hsu CH, Chou YC, Lin YW, Shih YL. A Novel Prognostic DNA Methylation Panel for Colorectal Cancer. Int J Mol Sci 2019 Sep 20;20(19). pii: E4672. doi: 10.3390/ijms20194672 (2018 JCR SCI, IF= 4.183, 78/298=26.2%, Biochemistry & Molecular Biology)
35.Liu IL, Tsai CH, Hsu CH, Hu JM, Chen YC, Tian YF, You SL, Chen CY, Hsiao CW, Lin CY, Chou YC*, Sun CA*. Helicobacter pylori infection and the risk of colorectal cancer: a nationwide population-based cohort study. QJM 2019 Oct 1;112(10):787-792. doi: 10.1093/qjmed/hcz157. (2018 JCR SCI, IF= 2.649, 42/160=26.3%, Medicine, General & Internal) (Corresponding author)
36.Wu WT, Tsai CT, Chou YC, Ku PM, Chen YC, You SL, Hung CF, Sun CA. Cardiovascular Outcomes Associated With Clinical Use of Citalopram and Omeprazole: A Nationwide Population-Based Cohort Study. J Am Heart Assoc 2019 Oct 15;8(20):e011607. doi: 10.1161/JAHA.118.011607. (2018 JCR SCI, IF= 4.660, 34/136=25%, Cardiac & Cardiovascular Systems)
37.Pan KT, Shen CH, Lin FG, Chou YC, Croxford B, Leonardi G, Huang KL. Prognostic factors of carbon monoxide poisoning in Taiwan: a retrospective observational study. BMJ Open 2019 Nov 18;9(11):e031135. doi: 10.1136/bmjopen-2019-031135. (2018 JCR SCI, IF= 2.376, 50/160=31.3%, Medicine, General & Internal)
38.Wang HE, Liao YC, Hu JM, Wu WC, Chou WY, Chen YC, Chou YC, Hung CF, Tian YF, You SL, Sun CA. Correlation between kidney transplantation and colorectal cancer in hemodialysis patients: A nationwide, retrospective, population-based cohort study. BMC Cancer 2019 Nov 16;19(1):1120. doi: 10.1186/s12885-019-6283-z. (2019 JCR SCI, IF= 3.150, 129/244=53%, Oncology)
39.Lai YJ, Chou YC, Lin YJ, Yu MH, Ou YC, Chu PW, Wu CC, Wang YC, Chao TK*. Pyruvate Kinase M2 Expression: A Potential Metabolic Biomarker to Differentiate Endometrial Precancer and Cancer That Is Associated with Poor Outcomes in Endometrial Carcinoma. Int J Environ Res Public Health 2019 Nov 20;16(23). pii: E4589. doi: 10.3390/ijerph16234589. (2018 JCR SCI, IF= 2.468, 67/185=36.3%, Public, Environmental &Occupational Health)
40.Shen YP, Li TY, Chou YC, Ho TY, Ke MJ, Chen LC, Wu YT. Comparison of perineural platelet-rich plasma and dextrose injections for moderate carpal tunnel syndrome: A prospective randomized, single-blind, head-to-head comparative trial. J Tissue Eng Regen Med 2019 Nov;13(11):2009-2017. doi: 10.1002/term.2950. Epub 2019 Aug 20. (2018 JCR SCI, IF= 3.319, 16/26=61.6%, Cell & Tissue Engineering)
41.Chen YH, Wang V, Huang EY, Chou YC, Kuo TT, Olson L, Hoffer BJ. Delayed Dopamine Dysfunction and Motor Deficits in Female Parkinson Model Mice. Int J Mol Sci 2019 Dec 11;20(24). pii: E6251. doi: 10.3390/ijms20246251(2018 JCR SCI, IF= 4.183, 78/298=26.2%, Biochemistry & Molecular Biology)
42.Chou YC, You SL, Bai CH, Liao YC, Wei CY, Sun CA. Utility of apolipoprotein measurements in predicting incident type 2 diabetes: A Chinese cohort study. J Formos Med Assoc 2020 Jan;119(1 Pt 1):51-58. doi: 10.1016/j.jfma.2019.03.001. Epub 2019 Mar 21 (2019 JCR SCI, IF= 3.008, 42/165=26%, Medicine, General & Internal) (First author)
43.Hsu CH, Hsiao CW, Sun CA, Wu WC, Yang T, Hu JM, Liao YC, Huang CH, Chen CY, Lin FH, Chou YC*. Multiple gene promoter methylation and clinical stage in adjacent normal tissues: Effect on prognosis of colorectal cancer in Taiwan. Sci Rep 2020 Jan 10;10(1):145. doi: 10.1038/s41598-019-56691-6. (2019 JCR SCI, IF= 3.998, 17/71=24%, Multidisciplinary sciences) (Corresponding author)
44.Hsu CH, Hsiao CW, Sun CA, Wu WC, Yang T, Hu JM, Huang CH, Liao YC, Chen CY, Lin FH, Chou YC*. Novel methylation gene panel in adjacent normal tissues predicts poor prognosis of colorectal cancer in Taiwan. World J Gastroenterol 2020 January 14; 26(2): 154-167. (2019 JCR SCI, IF= 3.665, 35/88=39.8%, Gastroenterology & Hepatology) (Corresponding author)
45.Liu WH, Lin JC, Chou YC, Li MH, Tsai JT. CD44-associated radioresistance of glioblastoma in irradiated brain areas with optimal tumor coverage. Cancer Med 2020 Jan;9(1):350-360. doi: 10.1002/cam4.2714. Epub 2019 Nov 19. (2019 JCR SCI, IF= 3.491, 111/244=45.5%, Oncology)
46.Ding JJ, Lin SH, Huang JL, Wu TW, Hsia SH, Lin JJ, Chou YC, Tseng MH. Risk factors for complications of percutaneous ultrasound-guided renal biopsy in children. Pediatr Nephrol 2020 Feb;35(2):271-278. doi: 10.1007/s00467-019-04367-8. (2019 JCR SCI, IF= 2.676, 28/128=21.9%, Pediatrics)
47.Chen CY, Hu JM, Shen CJ, Chou YC, Tian YF, Chen YC, You SL, Hung CF, Lin TC, Hsiao CW, Lin CY, Sun CA. Increased incidence of colorectal cancer with obstructive sleep apnea: a nationwide population-based cohort study. Sleep Med 2020 Feb; 66:15-20. doi: 10.1016/j.sleep.2019.02.016. Epub 2019 Mar 7. (2019 JCR SCI, IF= 3.038, 80/204=39.2%, Clinical Neurology)
48.Chou YC, Lin CH, Wong CS*, Chou WY, Chang JY, Sun CA*. Statin use and the risk of renal cell carcinoma: national cohort study. J Investig Med 2020 Mar;68(3):776-781. doi: 10.1136/jim-2019-001209. Epub 2019 Dec 9. (2019 JCR SCI, IF= 2.304, 60/165=36.4%, Medicine, General & Internal) (First author)
49. Wu WC, Lai YW, Chou YC, Liao YC, You SL, Bai CH, Sun CA. Serum Uric Acid Level as a Harbinger of Type 2 Diabetes: A Prospective Observation in Taiwan. Int J Environ Res Public Health 2020 Mar 28;17.pii: E2277; doi:10.3390/ijerph17072277. (2019 JCR SCI, IF= 2.849, 58/193=30.1%, Public, Environmental &Occupational Health)
50.Chou YC, Hsieh CJ, Cheng CA, Wu DC, Wu WC, Lin FH, Yu CP. Epidemiologic Characteristics of Imported and Domestic Chikungunya Cases in Taiwan: A 13-Year Retrospective Study. Int J Environ Res Public Health 2020 May 21;17(10):3615. doi: 10.3390/ijerph17103615. (2019 JCR SCI, IF= 2.849, 58/193=30.1%, Public, Environmental &Occupational Health) (First author)
51.Chung HH, Lee CT, Hu JM, Chou YC, Lin YW, Shih YL. NKX6.1 Represses Tumorigenesis, Metastasis, and Chemoresistance in Colorectal Cancer. Int J Mol Sci 2020 Jul 19;21(14):5106. doi: 10.3390/ijms21145106. (2019 JCR SCI, IF= 4.556, 74/297=24.9%, Biochemistry & Molecular Biology)
52.Hsieh CJ, Li CW, Cheng CA, Wu DC, Wu WC, Lin FH, Chou YC*, Yu CP*. Epidemiologic Characteristics of Domestic Patients with Hemorrhagic Fever with Renal Syndrome in Taiwan: A 19-Year Retrospective Study. Int J Environ Res Public Health 2020 Jul 22;17(15):E5291. doi: 10.3390/ijerph17155291. (2019 JCR SCI, IF= 2.849, 58/193=30.1%, Public, Environmental &Occupational Health) (Corresponding author)
53.Chang CY, Chen LC, Chou YC, Li TY, Ho TY, Wu YT. The Effectiveness of Platelet-Rich Plasma and Radial Extracorporeal Shock Wave Compared with Platelet-Rich Plasma in the Treatment of Moderate Carpal Tunnel Syndrome. Pain Med 2020 Aug 1;21(8):1668-1675. doi: 10.1093/pm/pnz309. (2019 JCR SCI, IF= 2.513, 51/165=31%, Medicine, General & Internal)
54.Liu LC, Tsai YH, Chou YC, Jheng YC, Lin CK, Lyu NY, Chien Y, Yang YP, Chang KJ, Chang KH, Wang PH, Chu TW, Chang CC. Concordance analysis of intrapartum cardiotocography between physicians and Artificial Intelligence (AI)-based technique using modified 1D Fully Convolutional Networks (FCN). J Chin Med Assoc 2020 Aug 20. doi: 10.1097/JCMA.0000000000000416. [Online ahead of print] (2019 JCR SCI, IF= 2.170, 63/165=44%, Medicine, General & Internal)
55.Chou YC, Chan PC, Yang T, You SL, Bai CH, Sun CA. Apolipoprotein B Level and the Apolipoprotein B/Apolipoprotein A-I Ratio as a Harbinger of Ischemic Stroke: A Prospective Observation in Taiwan. Cerebrovasc Dis 2020 Sep 18:1-8. doi: 10.1159/000509452. [Online ahead of print] (2019 JCR SCI, IF= 2.698, 31/65=48%, Peripheral Vascular Disease) (First author)