Other Info
Publications:
(*correspondence)
Lin, Y.-C., Liao, Y.-J., Lee, Y.-H., Tseng, S.-F., Liu, J.-Y., Chen, Y.-S., Shui, H.-A., Lin, F.-Z., Lin, K.-H., Chen, Y.-C., Tsai, M.-C., Sytwu, H.-K., Wang, C.-C., Chuang, Y.-P. (2019) Staphylococcal Phosphatidylinositol-Specific Phospholipase C potentiates lung injury via complement sensitization. Cellular Microbiology. 21(10), e13085
Lin, G.-J., Wu, C.-H., Yu, C.-C., Lin, J.-R., Liu, X.-D., Chen, Y.-W., Chang, H.-M., Hong, Z.-J., Cheng, C.-P., Sytwu, H.-K., Huang, S.-H. (2019) Adoptive transfer of D">Toxicology and Applied Pharmacology 378:114641
Yang, C.-Y., Lin, C.-K., Hsieh, C.-C., Tsao, C.-H., Lin, C.-S., Peng, B., Chen, Y.-T., Ting, C.-C., Chang, W.-C., Lin, G.-J., Sytwu, H.-K., Chen, Y.-W. (2019) Anti-oral cancer effects of triptolide by downregulation of DcR3 in vitro, in vivo, and in preclinical patient-derived tumor xenograft model. Head & Neck 2019 41(5):1260-1269
Chen, S.-J., Lin, G.-J., Chen, J.-W., Wang, K.-C., Tien, C.-H., Hu, C.-F., Chang, C.-N., Hsu, W.-F., Fan, H.-C., *Sytwu, H.-K. (2019) Immunopathogenic Mechanisms and Novel Immune-Modulated Therapies in Rheumatoid Arthritis. International Journal of Molecular Sciences 20(6), 1332
Chen, F.-J., Huang, W.-C., Liao, Y.-C., Wang, H.-Y., Lai, J.-F., Kuo, S.-C., Lauderdale, T.-L., Sytwu, H.-K. (2019) Molecular Epidemiology of Emerging Carbapenem Resistance in Acinetobacter nosocomialis and Acinetobacter pittii in Taiwan, 2010-2014. Antimicrob Agents Chemother 63(4) e02007-18
Wu, Y.-F., *Sytwu, H.-K., *Lung, F.-W. (2018) Human Aquaporin 4 Gene Polymorphisms and Haplotypes Are Associated With Serum S100B Level and Negative Symptoms of Schizophrenia in a Southern Chinese Han Population. Frontiers in Psychiatry 11:657
Hsu, C.-F., Hsiao, C.-H., Tseng, S.-F., Chen, J.-R., Liao, Y.-J., Chen, S.-J., Lin, C.-S., Sytwu, H.-K., Chuang, Y.-P. (2018) PrtA immunization fails to protect against pulmonary and invasive infection by Streptococcus pneumoniae. Respiratory Research 19:187
Chen, H.-K., Zhang, S.-M., Chang, J.-L., Chen, H.-C., Lin, Y.-C., Shih, C.-P., Sytwu, H.-K., Fang, M.-C., Lin, Y.-Y., Kuo, C.-Y., Liao, A.-H., Chu, Y.-H., Wang, C.-H. (2018) Insonation of Systemically Delivered Cisplatin-Loaded Microbubbles Significantly Attenuates Nephrotoxicity of Chemotherapy in Experimental Models of Head and Neck Cancer. Cancers 10(9) 311
Hsu, C.-Y., Yeh, L.-T., Fu, S.-H., Chien, M.-W., Liu, Y.-W., Miaw, S.-C., Chang, D.-M., *Sytwu, H.-K. (2018) SUMO-defective c-Maf preferentially transactivates Il21 to exacerbate autoimmune diabetes. The Journal of Clinical Investigation 128(9):3779-3793
Huang, Y.-S., Lu, K.-C., Chao, T.-K., Chen, J.-S., Chen, A., Guo, C.-Y., Hsieh, H.-Y., Shih, H.-M., Sytwu, H.-K., Wu, C.-C. (2018) Role of MTNR1A and PITX1 coexpression in protecting tubular epithelial cells in membranous nephropathy.
Journal of Pineal Research 65(1):e12482
Wang, A. Y.-L., Loh, C. Y.-Y., Chen, S.-J., Kao, H.-K., Lin, C.-H., Chuang, S.-H., Lee, C.-M., Sytwu, H.-K., Wei, F.-C. (2018) Blimp-1 prolongs allograft survival without regimen via influencing T cell development in favor of regulatory T cells while suppressing Th1. Molecular Immunology 99:53-65
Wang, A. Y.-L., Loh, C. Y.-Y., Chen, S.-J., Kao, H.-K., Lin, C.-H., Chuang, S.-H., Lee, C.-M., Sytwu, H.-K., Wei, F.-C. (2018) Characterization data for T cell-specific Blimp-1 transgenic C57BL/6 mice. Data in Brief 119:117-127
Wang, L.-T., Jiang, S.-S., Ting, C.-H., Hsu, P.-J., Chang, C.-C., Sytwu, H.-K., Liu, K.-J., Yen, B.-L. (2018) Differentiation of Mesenchymal Stem Cells from Human Induced Pluripotent Stem Cells Results in Downregulation of c-Myc and DNA Replication Pathways with Immunomodulation Toward CD4 and CD8 Cells. Stem Cells 36:903-914
Chien, M.-W., Fu, S.-H., Hsu, C.-Y., Liu, Y.-W., *Sytwu, H.-K. (2018) The Modulatory Roles of N-glycans in T-Cell-Mediated Autoimmune Diseases. International Journal of Molecular Sciences 19(3), 780
Chou, F.-C., Chen, H.-Y., Kuo, C.-C., *Sytwu, H.-K. (2018) Roles of Galectins in Tumors and in Clinical Immunotherapy. International Journal of Molecular Sciences 19(2), 430
Huang, Y.-S., Fu, S.-H., Lu, K.-C., Chen, J.-S., Hsieh, H.-Y., Sytwu, H.-K., Wu, C.-C. (2017) Inhibition of tumor necrosis factor signaling attenuates renal immune cell infiltration in experimental membranous nephropathy. Oncotarget 8:111631-111641
Yang, C.-Y., Hsieh, C.-C., Lin, C.-K., Lin, C.-S., Peng, B., Lin, G.-J., Sytwu, H.-K., Chang, W.-L., Chen, Y.-W. (2017) Danshen extract circumvents drug resistance and represses cell growth in human oral cancer cells. BMC Complementary and Alternative Medicine 17:555
Chou, F.-C., Chen, H.-Y., Chen, H.-H., Lin, G.-J., Lin, S.-H., *Sytwu, H.-K. (2017) Differential Modulation of IL-12 Family Cytokines in Autoimmune Islet Graft Rejection. Diabetologia 60:2409-2417
Divakar Kulshrestha, Yeh, L.-T., Chien, M.-W., Chou, F.-C., *Sytwu, H.-K. (2017) Peripheral autoimmune regulator induces exhaustion of CD4+ and CD8+ effector T cells to attenuate autoimmune diabetes in NOD mice. Frontiers in Immunology 8:1128
Fu, S.-H., Yeh, L.-T., Chu, C.-C., Yen, B.-L., *Sytwu, H.-K. (2017) New insights into Blimp-1 in T lymphocytes: a divergent regulator of cell destiny and effector function. Journal of Biomedical Science 24:49
Yang, C.-Y., Lin, C.-K., Tsao, C.-H., Hsieh, C.-C., Lin, G.-J., Ma, K.-H., Shieh, Y.-S., Sytwu, H.-K., Chen, Y.-W. (2017) Melatonin exerts anti-oral cancer effect via suppressing LSD1 in patient-derived tumor xenograft models. Oncotarget 8:33756-33769
Lee, H.-T., Liu, S.-P., Lin, C.-H., Lee, S.-W., Hsu, C.-Y., Sytwu, H.-K., Hsieh, C.-H., Shyu, W.-C. (2017) A Crucial Role of CXCL14 for Promoting Regulatory T Cells Activation in Stroke. Theranostics 7:855-875
Yang, C.-Y., Lin, C.-K., Lin, G.-J., Hsieh, C.-C., Huang, S.-H., Ma, K.-H., Shieh, Y.-S., Sytwu, H.-K., Chen, Y.-W. (2017) Triptolide represses oral cancer cell proliferation, invasion, migration, and angiogenesis in co-inoculation with U937 cells. Clinical Oral Investigations 21:419-427
Peng, Y.-J., Wang, C.-Y., Lin, Y.-H., Lin, G.-J., Huang, S.-H., Shyu, J.-F., Sytwu, H.-K., Cheng, C.-P. (2016) Interleukin 26 suppresses receptor activator of nuclear factor κB ligand induced osteoclastogenesis via down-regulation of nuclear factor of activated T-cells, cytoplasmic 1 and nuclear factor κB activity. Rheumatology 55:2074-2083
Liu, Y.-L., Yang, S.-S., Chen, S.-J., Lin, Y.-C., Chu, C.-C., Huang, H.-H., Chang, F.-W., Yu, M.-H., Lin, S.-H., Wu, G.-J., *Sytwu, H.-K. (2016) OSR1 and SPAK cooperatively modulate Sertoli cell support of mouse spermatogenesis. Scientific Reports 6：37205
Wang, L.-T., Ting, C.-H., Yen, M.-L., Liu, K.-J., Sytwu, H.-K., Wu, K.-K., Yen, B. L. (2016) Human mesenchymal stem cells (MSCs) for treatment towards immune- and inflammation-mediated diseases: review of current clinical trials. Journal of Biomedical Science 23:76
Liao, A.-H., Lu, Y.-J., Lin, Y.-C., Chen, H.-K., Sytwu, H.-K., Wang, C.-H. (2016) Effectiveness of a Layer-by-Layer Microbubbles-Based Delivery System for Applying Minoxidil to Enhance Hair Growth. Theranostics 6:817-827
Chou, F.-C., Kuo, C.-C., Chen, H.-Y., Chen, H.-H., *Sytwu, H.-K. (2016) DNA demethylation of the Tim-3 promoter is critical for its stable expression on T cells. Genes and Immunity 17, 179-186
Lin, G.-J., Huang, Y.-S., Lin, C.-K., Huang, S.-H., Shih, H.-M., Sytwu, H.-K., Chen, Y.-W. (2016) Daxx and TCF4 interaction links to oral squamous cell carcinoma growth by promoting cell cycle progression via induction of cyclin D1 expression. Clinical Oral Investigations 20:533-540
Wu, C.-C., Liu, F.-L., Sytwu, H.-K., Tsai, C.-Y., Chang, D.-M. (2016) CD146+ mesenchymal stem cells display greater therapeutic potential than CD146- cells for treating collagen-induced arthritis in mice. Stem Cell Research Therapy 7:23
Chen, S.-J., Huang, S.-H., Chen, J.-W., Wang, K.-C., Yang, Y.-R., Liu, P.-F., Lin, G.-J., Sytwu, H.-K. (2016) Melatonin enhances interleukin-10 expression and suppresses chemotaxis to inhibit inflammation in situ and reduce the severity of experimental autoimmune encephalomyelitis. International Immunopharmacology 31:169-177
Hsu, P.-J., Liu, K.-J., Chao, Y.-Y., Sytwu, H.-K., Yen, B.L. (2015) Assessment of the immunomodulatory properties of human mesenchymal stem cells (MSCs). Journal of Visualized Experiments 106:53265
Ka, S.-M., Lin, J.-C., Lin, T.-J., Liu, F.-C., Chao, L.-K., Ho, C.-L., Yeh, L.-T., Sytwu, H.-K., Hua, K.-F., Chen, A. (2015) Citral alleviates an accelerated and severe lupus nephritis model by inhibiting the activation signal of NLRP3 inflammasome and enhancing Nrf2 activation. Arthritis Research & Therapy 17:331
Chien, M.-W., Lin, M.-H., Huang, S.-H., Fu, S.-H., Hsu, C.-Y., Yen, B.-L., Chen, J.-T., Chang, D.-M., *Sytwu, H.-K. (2015) Glucosamine modulates T cell differentiation through downregulating N-linked glycosylation of CD25. The Journal of Biological Chemistry 290:29329-29344
Chen, H.-C., Lee, J.-T., Shih, C.-P., Chao, T.-T., Sytwu, H.-K., Li, S.-L., Fang, M.-C., Chen, H.-K., Lin, Y.-C., Kuo, C.-Y., Wang, C.-H. (2015) Hypoxia Induces a Metabolic Shift and Enhances the Stemness and Expansion of Cochlear Spiral Ganglion Stem/Progenitor Cells. BioMed Research International 2015;359537.
Wang, W.-B., Yen, M.-L., Liu, K.-J., Hsu, P.-J., Lin, M.-H., Chen, P.-M., Sudhir, P.-R., Chen, C.-H., Chen, C.-H., Sytwu, H.-K., Yen, B.-L. (2015) Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses. Stem Cell Reports 5:392-404
Tsai, P.-J., Wang, H.-S., Lin, G.-J., Chou, S.-C., Chu, T.-H., Chuan, W.-T., Lu, Y.-J., Weng, Z.-C., Su, C.-H., Hsieh, P.-S., Sytwu, H.-K., Lin, C.-H., Chen, T.-H., Shyu, J.-F. (2015) Undifferentiated Wharton’s Jelly Mesenchymal Stem Cell Transplantation Induces Insulin-Producing Cell Differentiation and Suppression of T Cell-Mediated Autoimmunity in Non-Obese Diabetic Mice. Cell Transplant 24:1555-1570
Tseng, F.-J., Chia, W.-T., Wang, C.-H., Shyu, J.-F., Gou, G.-H., Shui, H.-A., Sytwu, H.-K., Pan, R.-Y., Weng, C.-F. (2015) Carbon Monoxide Inhibits Receptor Activator of NF-κB (RANKL)-Induced Osteoclastogenesis. Cellular Physiology and Biochemistry 36:1250-1258.
Wu, C.-C., Huang, Y.-S., Chen, J.-S., Huang, C.-F., Su, S.-L., Lu, K.-C., Lin, Y.-F., Chu, P., Lin, S.-H., Sytwu, H.-K. (2015) Resveratrol Ameliorates Renal Damage, Increases Expression of Heme Oxygenase-1, and Has Anti-Complement, Anti-Oxidative, and Anti-Apoptotic Effects in a Murine Model of Membranous Nephropathy. PLoS One 2015 May 8;10(5):e0125726.
Fu, S.-H., Lin, M.-H., Yeh, L.-T., Wang, Y.-L., Chien, M.-W., Lin, S.-H., Chang, D.-M., *Sytwu, H.-K. (2015) Targeting tumor necrosis factor receptor 1 assembly reverses Th17-mediated colitis through boosting a Th2 response. Gut 64:765-775.
Hueng, D.-Y., Sytwu, H.-K. (2015) Letter to the Editor: Fusion antibody Fc-endostatin. Journal of Neurosurgery 122:1249.
Chuang, Y.-P., Peng, Z.-R., Tseng, S.-F., Lin, Y.-C., Sytwu, H.-K., Hsieh, Y.-C. (2015) The impact of glpQ2 gene on virulence in a Streptococcus pneumoniae serotype 19AST320 strain. Infection and Immunity 83:682-692.
Cheng, C.-J., Sung, C.-C., Wu, S.-T., Lin, Y.-C., Sytwu, H.-K., Huang, C.-L., Lin, S.-H. (2015) Novel KCNJ5 mutations in sporadic aldosterone-producing adenoma reduce Kir3.4 membrane abundance. The Journal of Clinical Endocrinology & Metabolism 100:E155-163.
Li, C.-H., Lin, M.-H., Chu, S.-H., Tu, P.-H., Fang, C.-C., Yen, C.-H., Liang, P.-I., Huang, J.-C., Su, Y.-C., Sytwu, H.-K., Chen, Y.-M. (2014) Role of glycine N-methyltransferase in the regulation of T cell responses in experimental autoimmune encephalomyelitis. Molecular Medicine 20:684-696
Yeh, L.-T., Chuang, Y.-P., Chen, S.-J., Chu, C.-C., *Sytwu, H.-K. (2014) Diabetic animal models with infectious diseases: focus on the dysfunction of immune system. Journal of Diabetes & Metabolism 2014. 5:8
Lin, G.-J., Sytwu, H.-K., Yu, J.-C., Chen, Y.-W., Kuo, Y.-L., Yu, C.-C., Chang, H.-M., Chan, D.-C., Huang, S.-H. (2014) Dimethyl sulfoxide inhibits spontaneous diabetes and autoimmune recurrence in non-obese diabetic mice by inducing differentiation of regulatory T cells. Toxicology and applied pharmacology 282:207-214.
Chen, C.-L., Liu, F.-L., Lee, C.-C., Chen, T.-C., Ahmed Ali AA, Sytwu, H.-K., Chang, D.-M., Huang, H.-S. (2014) Modified Salicylanilide and 3-Phenyl-2H-benzo[e][1,3]oxazine-2,4(3H)-dione Derivatives as novel inhibitors of osteoclast differentiation and bone resorption. Journal of Medicinal Chemistry 57:8072-8085.
Huang, Y.-S., Hsieh, H.-Y. , Shih, H.-M., Sytwu, H.-K., Wu, C.-C. (2014) Urinary Xist is a potential biomarker for membranous nephropathy. Biochemical and Biophysical Research Communications 452:415-421.
Chen, Y.-W., Huang, H.-S., Shieh, Y.-S., Ma, K.-H., Huang, S.-H., Hueng, D.-Y., Sytwu, H.-K., Lin, G.-J. (2014) A Novel Compound NSC745885 Exerts an Anti-Tumor Effect on Tongue Cancer SAS Cells In Vitro and In Vivo. PLoS One 2014;9(8):e104703.
Chen, P.-I., Liu, K.-J., Hsu, P.-J., Wei, C.-F., Bai, C.-H., Ho, L.-J., Sytwu, H.-K., Yen, B.L. (2014) Induction of immunomodulatory monocytes by human mesenchymal stem cell-derived hepatocyte growth factor through ERK1/2. Journal of Leukocyte Biology 96:295-303.
Tseng, F.-J., Chia, W.-T., Shyu, J.-F., Gou, G.-H., Sytwu, H.-K., Hsia, C.-W., Tseng, M.-J., Pan, R.-Y. (2014) Interactomics profiling of the negative regulatory function of carbon monoxide on RANKL-treated RAW 264.7 cells during osteoclastogenesis. BMC Systems Biology 8:57.
Hueng, D.-Y., Lin, G.-J., Sytwu, H.-K. (2014) Letter to the Editor: Glioma immunoenvironment. Journal of Neurosurgery 120:1012-1013.
Chen, Y.-W., Lin, G.-J., Hueng, D.-Y., Huang, S.-H., Chia, W.-T., Shieh, Y.-S., Ma, K.-H., Sytwu, H.-K. (2014) Enhanced Anti-Tumor Activity of Triptolide in Combination with Irradiation for the Treatment of Oral Cancer. Planta Medica 80:255-261.
Lin, M.-H., Yeh, L.-T., Chen, S.-J., Chiou, H.-Y., *Chu, C.-C., Yen, B.L., Lin, K.-I., Chang, D.-M., *Sytwu, H.-K. (2014) T cell-specific BLIMP-1 deficiency exacerbates experimental autoimmune encephalomyelitis in nonobese diabetic mice by increasing Th1 and Th17 cells. Clinical Immunology 151:101–113.
Hueng, D.-Y., Sytwu, H.-K. (2014) Letter to the editor: Vestibular schwannoma growth and hearing loss. Journal of Neurosurgery 120:786.
Hueng, D.-Y., Li, Y.-F., Sytwu, H.-K. (2014) Letter to the editor: Atypical meningiomas. Journal of Neurosurgery 120:781.
Feng, S.-W., Sytwu, H.-K., Hueng, D.-Y. (2014) Letter to the editor: Cell transplantation. Journal of Neurosurgery 120:574.
Hueng, D.-Y., Sytwu, H.-K. (2014) Letter to the editor: Blood-brain barrier. Journal of Neurosurgery 120:290-291.
Cheng, C.-H., Hong, C.-W., Yang, C.-H., Wu, Y.-J., Lee, C.-H., Sytwu, H.-K., Hueng, D.-Y. (2013) Letter to the editor: Glioblastoma. Journal of Neurosurgery 119:1641
Chou, F.-C., Kuo, C.-C., Wang, Y.-L., Lin, M.-H., Yen, B.L., *Sytwu, H.-K. (2013) Overexpression of Galectin-9 in Islets Prolongs Grafts Survival via Downregulation of Th1 Responses. Cell Transplantation 22:2135-2145.
Yang, S.-S., Fang, Y.-W., Tseng, M.-H., Chu, P.-Y., Yu, I.-S., Wu, H.-C., Lin, S.-W., Chau, T., Uchida S, Sasaki S, Lin, Y.-F., Sytwu, H.-K., Lin, S.-H. (2013) Phosphorylation Regulates NCC Stability and Transporter Activity In Vivo. J Am Soc Nephrol 24:1587-1597.
Tsai, W.-C., Chen, Y., Huang, L.-C., Lee, H.-S., Ma, H.-I., Huang, S.-M., Sytwu, H.-K., Hueng, D.-Y. (2013) EMMPRIN expression positively correlates with WHO grades of astrocytomas and meningiomas. Journal of Neuro-oncology 114:281-290.
Yen, B.L., Yen, M.-L., Hsu, P.-J., Liu, K.-J., Wang, C.-J., Bai, C.-H., Sytwu, H.-K. (2013) Multipotent Human Mesenchymal Stromal Cells Mediate Expansion of Myeloid-Derived Suppressor Cells via Hepatocyte Growth Factor/c-Met and STAT3. Stem Cell Reports 1:139-151.
Yeh, L.-T., Maiw, S.-C., Lin, M.-H., Chou, F.-C., Shieh, S.-J., Chuang, Y.-P., Lin, S.-H., Chang, D.-M., *Sytwu, H.-K. (2013) Different modulation of Ptpn22 on effector and regulatory T cells leads to attenuation of autoimmune diabetes in transgenic non-obese diabetic mice. Journal of Immunology 191:594-607.
Wang, K.-C., Tsai, C.-P., Lee, C.-L., Chen, S.-Y., Lin, G.-J., Yen, M.-H., Sytwu, H.-K., Chen, S.-J. (2013) Alpha lipoic acid enhances endogenous peroxisome proliferator-activated receptor-γ to ameliorate experimental autoimmune encephalomyelitis. Clinical Science 125:329-340.
Lin, G.-J., Huang, S.-H., Chen, S.-J., Wang, C.-H., Chang, D.-M., *Sytwu, H.-K. (2013) Modulation by Melatonin of the Pathogenesis of Inflammatory Autoimmune Diseases. International Journal of Molecular Sciences 14:11742-11766.
Hueng, D.-Y., Ma, H.-I., Sytwu, H.-K. (2013) Letter to the Editor: Chordoma. Journal of Neurosurgery: Spine 18:533-534.
Chao, T.-T., Wang, C.-H., Chen, H.-C., Shih, C.-P., Sytwu, H.-K., Huang, K.-L., Chen, S.-Y. (2013) Adherent culture conditions enrich the side population obtained from the cochlear modiolus-derived stem/progenitor cells. International Journal of Pediatric Otorhinolaryngology 77:779-784.
Lee, C.-H., Chang, W.-C., Yeh, C.-C., Jiang, P.-J., Sytwu, H.-K., Hueng, D.-Y. (2013) Letter to the Editor: Chordoma stem cells. Journal of Neurosurgery 118:913-914.
Chiu, S.-H., Wang, I.-D., Sytwu, H.-K., Hueng, D.-Y. (2013) Letter to the Editor: Atypical meningioma. Journal of Neurosurgery 118:912-913.
Cheng, C.-P., Sheu, M.-J., Sytwu, H.-K., Chang, D.-M. (2013) Decoy receptor 3 suppresses RANKL-induced osteoclastogenesis via down-regulating NFATc1 and enhancing cell apoptosis. Rheumatology 52:609-622.
Huang, S.-H., Lin, G.-J., Chu, C.-H., Yu, J.-C., Chen, T.-W., Chen, Y.-W., Chien, M.-W., Chu, C.-C., *Sytwu, H.-K. (2013) Triptolide ameliorates autoimmune diabetes and prolongs islet graft survival in nonobese diabetic mice. Pancreas 42:442-451.
Huang, S.-H., Lin, G.-J., Chien, M.-W., Chu, C.-H., Yu, J.-C., Chen, T.-W., Hueng, D.-Y., Liu, Y.-L., *Sytwu, H.-K. (2013) Adverse Effect on Syngeneic Islet Transplantation by Transgenic Co-expression of Decoy Receptor 3 and Heme Oxygenase-1 in the Islet of NOD Mice. Transplantation Proceedings 45:580-584.
Chou, F.-C., Chen, H.-Y., Chen, S.-J., Fang, M.-C., *Sytwu, H.-K. (2013) Rodent Models for Investigating the Dysregulation of Immune Responses in Type 1 Diabetes. Journal of Diabetes Research 2013:138412.
Shih, C.-P., Chen, H.-C., Chen, H.-K., Chiang, M.-C., Sytwu, H.-K., Lin, Y.-C., Li, S.-L., Shih, Y.-F., Liao, A.-H., Wang, C.-H. (2013) Ultrasound-aided microbubbles facilitate the delivery of drugs to the inner ear via the round window membrane. Journal of Controlled Release 167:167-174.
Huang, Y.-S., Li, I.-H., Chueh, S.-H., Hueng, D.-Y., Tai, M.-C., Liang, C.-M., Lien, S.-B., Sytwu, H.-K., Ma, K.-H. (2013) Mesenchymal stem cells from rat olfactory bulbs can differentiate into cells with cardiomyocyte characteristics. Journal of Tissue Engineering and Regenerative Medicine 9:E191-201.
Lin, M.-H., Chou, F.-C., Yeh, L.-T., Fu, S.-H., Chiou, H.-Y., Lin, K.-I., Chang, D.-M., *Sytwu, H.-K. (2013) B lymphocyte-induced maturation protein 1 (BLIMP-1) attenuates autoimmune diabetes in NOD mice by suppressing Th1 and Th17 cells. Diabetologia 56:136-146.
Ou, C.-C., Chen, Y.-W., Hus, S.-C., Sytwu, H.-K., Loh, S.-H., Li, J.-W. Liu, J.- Y. (2013) Triptolide transcriptionally represses HER2 in ovarian cancer cells by targeting NF-kB. Evidence-Based Complementary and Alternative Medicine 2012:350239.
Hueng, D.-Y., Sytwu, H.-K. (2012) Letter to the Editor: Syringomyelia. Journal of Neurosurgery: Spine 18:202.
Dai, M.-S., Vassaux, G., Xu, M., You, R.-I., Hsieh, Y.-F., Ouisse, L.-H., Lo, K.-Y., Sytwu, H.-K., Chao, T.-Y. (2012) Early Treg suppression by a listeriolysin-O-expressing E. coli vaccine in heterologous prime-boost vaccination against cancer. Vaccine 30:6903-6911.
Hou, H.-S., Liao, C.-L., Sytwu, H.-K., Liao, N.-S., Huang, T.-Y., Hsieh, T.-Y., Chu, H.-C. (2012) Deficiency of Interleukin-15 Enhances Susceptibility to Acetaminophen-Induced Liver Injury in Mice. PLoS One 2012;7(9):e44880.
Hueng, D.-Y., Tsao, C.-H., Sytwu, H.-K., Chen, Y.-W. (2012) Letter to the editor: Brain Biopsy. Journal of Neurosurger. 117:384.
Hueng, D.-Y., Liang, C.-M., Sytwu, H.-K., Ma, S.-I. (2012) Letter to the editor: Tumor model. Journal of Neurosurgery 117:383.
Yo, Y.-T., Lin, Y.-W., Wang, Y.-C., Balch C, Huang, R.-L., Chan, M.-W., Sytwu, H.-K., Chen, C.-K., Chang, C.-C., Nephew KP, Huang, T., Yu, M.-H., Lai, H.-C. (2012) Growth inhibition of ovarian tumor-initiating cells by niclosamide. Molecular Cancer Therapeutics 11:1703-1712.
Lai, C.-Y., Lin, S.-Y., Wu, C.-K., Yeh, L.-T., Sytwu, H.-K., Miaw, S.-C. (2012) Tyrosine Phosphorylation of c-Maf Enhances the Expression of IL-4 Gene. Journal of Immunology 189:1545-1550.
Chuang, Y.-P., Wang, C.-H., Wang, N.-C., Chang, D.-M., *Sytwu, H.-K. (2012) Modulatory function of invariant natural killer T cells in systemic lupus erythematosus. Clinical and Developmental Immunology 2012:478429.
Chou, F.-C., Huang, S.-H., *Sytwu, H.-K. (2012) Genetically Engineered Islets and Alternative Sources of Insulin-producing Cells for Treating Autoimmune Diabetes: Quo Vadis? International Journal of Endocrinology 2012:296485.
Chen, S.-J., Wang, Y.-L., Fan, H.-C., Lo, W.-T., Wang, C.-C., *Sytwu, H.-K. (2012) Current Status of the Immunomodulation and Immunomediated Therapeutic Strategies for Multiple Sclerosis. Clinical and Developmental Immunology 2012:970789.
Chen, S.-J., Liu, Y.-L., *Sytwu, H.-K. (2012) Immunologic Regulation in Pregnancy: From Mechanism to Therapeutic Strategy for Immunomodulation. Clinical and Developmental Immunology 2012:258391.
Hueng, D.-Y., Sytwu, H.-K. (2012) Letter to the editor: Brain edema. Journal of Neurosurgery 116:688-689.
Yang, C.-T., Fu, B.-S., Wang, H.-Y., Sytwu, H.-K., Hueng, D.-Y. (2012) Letter to the editor: Glioma spheroids. Journal of Neurosurgery 116:691-693.
Wu, C.-C., Lu, K.-C., Lin, G.-J., Hsieh, H.-Y., Chu, P., Lin, S.-H., Sytwu. H.-K. (2012) Melatonin enhances endogenous heme oxygenase-1 and represses immune responses to ameliorate experimental murine membranous nephropathy. Journal of Pineal Research 52:460-469.
Wu, C.-C., Sytwu, H.-K., Lin, Y.-F. (2012) Cytokines in Diabetic Nephropathy. Advances in Clinical Chemistry 56:55-74.
Wu, C.-C., Lu, K.-C., Lin, Y.-F., Chen, J.-S., Huang, C.-F., Chen, C.-C., Lin, S.-H., Chu, P., Sytwu, H.-K. (2012) Pathogenic Role of Effector Cells and Immunoglobulins in Cationic Bovine Serum Albumin-Induced Membranous Nephropathy. Journal of Clinical Immunology 32:138-149.
Wu, C.-C., Wu, T.-C., Liu, F.-L., Sytwu, H.-K., Chang, D.-M. (2012) TNF-α inhibitor reverse the effects of human umbilical cord-derived stem cells on experimental arthritis by increasing immunosuppression. Cellular Immunology 273:30-40.
Lin, S.-H., Yu, I.-S., Jiang, S.-T., Lin, S.-W., Chu, P., Chen, A., Sytwu, H.-K., Sohara E, Uchida S, Sasaki S, Yang, S.-S. (2011) Impaired phosphorylation of Na+-K+-2Cl- cotransporter by oxidative stress-responsive kinase-1 deficiency manifests hypotension and Bartter-like syndrome. Proc Natl Acad Sci U S A. 108:17538-17543.
Ka, S.-M., Hsieh, T.-T., Lin, S.-H., Yang, S.-S., Wu, C.-C., Sytwu, H.-K., Chen, A. (2011) Decoy receptor 3 inhibits renal mononuclear leukocyte infiltration and apoptosis and prevents progression of IgA nephropathy in mice. American Journal of Physiology - Renal Physiology 301:1218-1230.
Cheng, C.-P., Sytwu, H.-K., Chang, D.-M. (2011) Decoy Receptor 3 Attenuates Collagen-induced Arthritis by Modulating T Cell Activation and B Cell Expansion. Journal of Rheumatology 38:2522-2535.
Wu, C.-C., Sytwu, H.-K., Lu, K.-C., Lin, Y.-F. (2011) Role of T Cells in Type 2 Diabetic Nephropathy. Experimental Diabetes Research 2011:514738.
Chen, P.-M., Yen, M.-L., Liu, K.-J., Sytwu, H.-K., Yen, B.L. (2011) Immunomodulatory properties of human adult and fetal multipotent mesenchymal stem cells. Journal of Biomedical Science 18:49.
Wang, Y.-L., Chou, F.-C., Chen, S.-J., Lin, S.-H., Chang, D.-M., *Sytwu, H.-K. (2011) Targeting pre-ligand assembly domain of TNFR1 ameliorates autoimmune diseases – an unrevealed role in downregulation of Th17 cells. Journal of Autoimmunity 37:160-170.
Liu, K.-J., Wang, C.-J., Chang, C.-J., Hu, H.-I., Hsu, P.-J., Wu, Y.-C., Bai, C.-H., Sytwu, H.-K., Yen, B.L. (2011) Surface expression of HLA-G is involved in mediating immunomodulatory effects of placenta-derived multipotent cells (PDMCs) towards natural killer lymphocytes. Cell Transplantation 20:1721-1730.
Hueng, D.-Y., Sytwu, H.-K., Huang, S.-M., Chang, C., Ma, H.-I. (2011) Isolation and characterization of tumor stem-like cells from human meningiomas. Journal of Neuro-oncology 104:45-53.
Hueng, D.-Y., Lin, G.-J., Huang, S.-H., Liu, L.-W., Ju, D.-T., Chen, Y.-W., Sytwu, H.-K., Chang, C., Huang, S.-M., Yeh, Y.-S., Lee, H.-M., Ma, H.-I. (2011) Inhibition of Nodal suppresses angiogenesis and growth of human gliomas. Journal of Neuro-oncology 104:21-31.
Lin, G.-J., Huang, S.-W., Chen, Y.-W., Hueng, D.-Y., Chia, W.-T., Chien, M.-W., Yen, B.L., *Sytwu, H.-K. (2011) Transgenic expression of murine chemokine decoy receptor D6 by islets reveals the role of inflammatory CC chemokines in the development of autoimmune diabetes in NOD mice. Diabetologia 54:1777-1787.
Hueng, D.-Y., Ma, H.-I., Sytwu, H.-K., Liu, M.-Y. (2011) Letters to the editor: Temozolomide and pituitary adenoma. Journal of Neurosurgery 114:1820-1821.
Chuang, Y.-P. Lin, Y.-C., *Sytwu, H.-K. (2011) α-Galactosylceramide ameliorates autoimmune diabetes in non-obese diabetic mice through a suppressive effect mediated by CD8+ T cells. Immunology Letters 138:54-62.
Lo, Y.-F., Nozu K, Iijima K, Morishita T, Huang, C.-C., Yang, S.-S., Sytwu, H.-K., Fang, Y.-W., Tseng, M.-H., Lin, S.-H. (2011) Recurrent Deep Intronic Mutations in the SLC12A3 Gene Responsible for Gitelman's Syndrome. Clin J Am Soc Nephrol 6:630-639.
Ma, H.-I., Chiou, S.-H., Hueng, D.-Y., Tai, L.-K., Huang, P.-I., Kao, C.-L., Chen, Y.-W., Sytwu H.-K. (2011) Celecoxib and Radioresistant Glioblastoma-derived CD133+ cells: improvement in radiotherapeutic effects. Journal of Neurosurgery 114:651-662.
Wu, C.-C., Chen, J.-S., Huang, C.-F., Chen, C.-C., Lu, K.-C., Chu, P., Sytwu, H.-K., Lin, Y.-F. (2011) Approaching biomarkers of membranous nephropathy from murine model to human disease. Journal of Biomedicine and Biotechnology 2011:581928.
Shyu, J.-F., Wang, H.-S., Shyr, Y.-M., Wang, S.-E., Chen, C.-H., Tan, J.-S., Lin, M.-F., Hsieh, P.-S., Sytwu, H.-K., Chen, T.-H. (2010) Alleviation of hyperglycemia in diabetic rats by intraportal injection of insulin-producing cells generated from surgically resected human pancreatic tissue. The Journal of Endocrinology 208:233-244.
Chen, H.-C., Sytwu, H.-K., Chang, J.-L., Wang, H.-W., Chen, H.-K., Kang, B.-H., Liu, D.-W., Chen, C.-H., Chao, T.-T., Wang, C.-H. (2010) Hypoxia enhances the stemness markers of cochlear stem/progenitor cells and expands sphere formation through activation of hypoxia-inducible factor-1alpha. Hearing Research 275:43-52.
Yang, S.-S., Lo, Y.-F., Yu, I.-S., Lin, S.-W., Chang, T.-H., Hsu, Y.-J., Chao, T.-K., Sytwu, H.-K., Shinichi Uchida, Sei Sasaki, Lin, S.-H. (2010) Generation and analysis of the thiazide-sensitive Na+-Cl- cotransporter S707X knockin mice as a model of Gitelman’s syndrome. Human Mutation 31:1304-1315.
Yang, S.-S., Lo, Y.-F., Wu, C.-C., Lin, S.-W., Yeh, C.-J., Chu, P., Sytwu, H.-K., Shinichi Uchida, Sei Sasaki, Lin, S.-H. (2010) SPAK knockout mice manifest Gitelman’s syndrome and impaired vasoconstriction. Journal of the Amercian Society of Nephrology 21:1868-1877.
Chia, W.-T., Pan, R.-Y., Tseng, F.-J., Chen, Y.-W., Feng, C.-K., Lin, G.-J., Liu, H.-H., Lee, H.-S., Chang, D.-M., *Sytwu, H.-K. (2010) Experimental osteoarthritis induced by surgical realignment of the patella in BALB/c mice. The Journal of Bone & Joint Surgery-BritishVolume 92-B(12):1710-1716.
Chen, S.-J. , Wang, Y.-L., Lo, W.-T., Wu, C.-C., Hsieh, C.-W. , Huang, C.-F., Lan, Y.-H., Wang, C.-C. , Chang, D.-M., Sytwu, H.-K. (2010) Erythropoietin enhances endogenous heme oxygenase-1 and represses immune responses to ameliorate experimental autoimmune encephalomyelitis. Clinical and Experimental Immunology 162:210-223.
Chen, H.-C., Ma, H.-I., Sytwu, H.-K., Wang, H.-W., Chen, C.-C., Liu, S.-C., Chen, C.-H., Chen, H.-K., Wang, C.-H. (2010) Neural stem cells secrete factors that promote auditory cell proliferation via a leukemia inhibitory factor signaling pathway. Journal of Neuroscience Research 88:3308-3318.
Wang, Y.-L., Chou, F.-C., Sung, H.-H., Fan, P.-L., Hsueh, C.-W., Lin, W.-C., Chen, S.-J., Lin, W.-W., *Sytwu, H.-K. (2010) Decoy receptor 3 protects non-obese diabetic mice from autoimmune diabetes by regulating dendritic cell maturation and function. Molecular Immunology 47:2552-2562.
Huang, S.-H., Chu, C.-H., Yu, J.-C., Chuang, W.-C., Lin, G.-J., Chen, P.-L., Chou, F.-C., Chau, L.-Y., *Sytwu, H.-K. (2010) Transgenic expression of haem oxygenase-1 in pancreatic beta cells protects non-obese mice used as a model of diabetes from autoimmune destruction and prolongs graft survival following islet transplantation. Diabetologia 53:2389–2400.
Tseng, K.-Y., Chung, M.-H., Sytwu H.-K., Lee, H.-M., Chen, K.-Y., Chang, C., Lin, C.-K., Yen, C.-H., Chen, J.-H., Lin, G.-J., Ma, H.-I., Yeh, Y.-S., Ju, D.-T., Liu, M.-Y., Hueng, D.-Y. (2010) Osteopontin expression is a valuable marker for prediction of short-term recurrence in WHO grade I benign meningiomas. Journal of Neuro-oncology 100: 217-223.
Chen, Y.-W., Lin, G.-J., Chuang, Y.-P., Chia, W.-T., Hueng, D.-Y., Lin, C.-K., Nieh, S., *Sytwu, H.-K. (2010) Triptolide circumvents drug-resistant effect and enhances 5-fluorouracil antitumor effect on KB cells. Anti-Cancer Drugs 21:502-513.
Wu, C.-C., Chen, J.-S., Lu, K.-C., Chen, C.-C., Lin, S.-H., Chu, P., Sytwu, H.-K., Lin, Y.-F.(2010) Aberrant cytokines/chemokines production correlate with proteinuria in patients with overt diabetic nephropathy. Clinica Chimica Acta 411:700-704.
Chia, W.-T., Lin, C.-F., Yeh, L.-T., Chang, D.-M., *Sytwu, H.-K. (2010) A noncontact footpad thickness assay to evaluate rheumatoid disease. Rheumatology International 30:547-550.
Liu, F.-L., Lin, L.-H., Sytwu, H.-K., Chang, D.-M. (2010) GDF-5 is suppressed by IL-1beta and enhances TGF-beta3-mediated chondrogenic differentiation in human rheumatoid fibroblast-like synoviocytes. Experimental and molecular pathology 88:163-170.
Chen, S.-J., Wang, Y.-L., Wu, S.-F., Wang, C.-C., Kao, J.-H., Tao, P.-L., Wu, C.-C., Chang, D.-M., *Sytwu, H.-K. (2009) Decoy receptor 3 ameliorates experimental autoimmune encephalomyelitis by directly counteracting local inflammation and downregulating Th17 cells. Molecular Immunology 47:567-574.
Lin, G.-J., Huang, S.-H., Chen, Y.-W., Hueng, D.-Y., Chien, M.-W., Chia, W.-T., Chang, D.-M., *Sytwu, H.-K. (2009) Melatonin prolongs islet graft survival in diabetic NOD mice. Journal of Pineal Research 47:284-292.
Shieh, S.-J., Chou, F.-C., Yu, P.-N., Lin, W.-C., Chang, D.-M., Roffler, S., *Sytwu, H.-K. (2009) Transgenic expression of single-chain anti-CTLA-4 Fv on beta cells protects NOD mice from autoimmune diabetes. Journal of Immunology 183:2277-2285.
Chou, F.-C., *Sytwu, H.-K. (2009) Overexpression of thioredoxin in islets by lentiviral vector prolongs graft survival in autoimmune diabetic NOD mice. Journal of Biomedical Science 16:71.
Chou, F.-C., Shieh, S.-J., *Sytwu, H.-K. (2009) Attenuation of Th1 cell immune response through galectin-9-TIM-3 interactions inhibits autoimmune diabetes in NOD mice. European Journal of Immunology 39:2403-2411.
Chen, Y.-W., Lin, G.-J., Chia, W.-T., Lin, C.-K., Chuang, Y.-P., *Sytwu, H.-K. (2009) Triptolide exerts anti-tumor effect on oral cancer and KB cells in vitro and in vivo. Oral Oncology 45:562-568.
Chia, W.-T., Yeh, L.-T., Lee, H.-S. Chang, D.-M. , *Sytwu, H.-K. (2009) IL-1b in irrigation fluid and mRNA expression in synovial tissue of the knee joint as therapeutic markers of inflammation in collagen antibody-induced arthritis. Disease Markers 26:1-7.
Dai, N.-T., Yeh, M.-K., Chiang, C.-H., Chen, K.-C., Liu, T.-H., Feng, A.-C., Chao, L.-L., Shih, C.-M., Sytwu, H.-K., Chen, S.-L., Chen, T.-M., Adams EF. (2009) Human single-donor composite skin substitutes based on collagen and polycaprolactone copolymer. Biochemical and Biophysical Research Communications 386:21-25.
Chung, M.-T., Lai, H.-C., Sytwu, H.-K., Yan, M.-D., Shih, Y.-L., Chang, C.-C., Yu, M.-H, Liu, H.-S., Chu, D.-W., Lin, Y.-W. (2009) SFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathway. Gynecologic Oncology 112:646-653.
Chung, M.-T., Sytwu, H.-K., Yan, M.-D., Shih, Y.-L., Chang, C.-C., Yu, M.-H., Chu, T.-Y., Lai, H.-C., Lin, Y.-W. (2009) Promoter methylation of SFRPs gene family in cervical cancer. Gynecologic Oncology 112:301-306.
Hsu, Y.-J., Yang, S.-S., Chu, N.-F., Sytwu, H.-K., Cheng, C.-J., Lin, S.-H. (2009) Heterozygous mutations of the sodium chloride cotransporter in Chinese children: prevalence and association with blood pressure. Nephrol Dial Transplant 24:1170-1175.
Wang, C.-J., Chou, F.-C., Chu, C,-H., Wu, J.-C., Lin, S.-H., Chang, D.-M., *Sytwu, H.-K. (2008) Protective role of programmed death 1 ligand 1 in nonobese diabetic mice: The paradox in transgenic models. Diabetes 57:1861-1869.
Chuang, Y.-P., Chu, C.-H., *Sytwu, H.-K. (2008) Genetic manipulation of islet cells in autoimmune diabetes: from bench to bedside. Frontiers in Bioscience-Landmark 13:6155-6169.
Chia, W.-T., Chen, Y.-W., Cheng, L.-Y., Lee, H.-S., Chang, D.-M., *Sytwu, H.-K. (2008) MMP-9 mRNA as a therapeutic marker in acute and chronic stages of arthritis induced by type II collagen antibody. Journal of the Formosan Medical Association 107:245-252.
Ho, T.-C., Yang, Y.-C., Chen, S.-L., Kuo, P.-C., Sytwu, H.-K., Cheng, H.-C., Tsao, Y.-P. (2008) Pigment epithelium-derived factor induces THP-1 macrophage apoptosis and necrosis by the induction of the peroxisome proliferator-activated receptor gamma. Molecular Immunology 45:898-909.
Wu, C.-C., Lu, K.-C., Chen, J.-S., Hsieh, H.-Y., Lin, S.-H., Chu, P., Wang, J.-Y., *Sytwu, H.-K. *Lin, Y.-F. (2008) HO-1 induction ameliorates experimental murine membranous nephropathy: anti-oxidative, anti-apoptotic, and immunomodulatory effects. Nephrol Dial Transplant 23:3082-3090.
Wu, C.-C., Chen, J.-S., Lin, S.-H., Chen, A., *Sytwu, H.-K. *Lin, Y.-F. (2008) Experimental model of membranous nephropathy in mice: Sequence of histologic and biochemical events. Laboratory Animals 42:350-359.
Wu, C.-C., Chen, J.-S., Chen, S.-J., Lin, S.-H., Chen, A., Chang, L.-C., *Sytwu, H.-K. *Lin, Y.-F. (2007) Kinetics of adaptive immunity to cationic bovine serum albumin induced membranous nephropathy: Evidence from diverse expression of double T1/T2 transgenes and Th1/Th2-related cytokines. Kidney International 72:831-840.
Ka, S.-M., Sytwu, H.-K., Chang, D.-M., Hsieh, S.-L., Tsai, P.-Y., Chen, A. (2007) Decoy receptor 3 ameliorates an autoimmune crescentic glomerulonephritis model in mice. Journal of the American Society of Nephrology 18:2473-2485.
Liu, F.-L., Chen, C.-H., Chu, S.-J., Chen, J.-H., Lai, J.-H., Sytwu, H.-K., Chang, D.-M. (2007) Interleukin (IL)-23 p19 expression induced by IL-1b in human fibroblast-like synoviocytes with rheumatoid arthritis via active nuclear factor-kB and AP-1 dependent pathway. Rheumatology 46:1266-1273.
Chen, Y.-C., Chen, S.-Y., Ho, P.-S., Lin, C.-H., Cheng, Y.-Y., Wang, J.-K., *Sytwu, H.-K. (2007) Apoptosis of T-leukemia and B-myeloma cancer cells induced by hyperbaric oxygen increased phosphorylation of p38 MAPK. Leukemia Research 31:805-815.
Chao, T.-K., Rifai, A., Ka, S.-M., Yang, S.-M., Shui, H.-A., Lin, Y.-F., Sytwu, H.-K., Lee, W.-H., Kung, J.T., Chen, A. (2006) The endogenous immune response modulates the course of IgA-immune complex mediated nephropathy. Kidney International 70:283-297.
Chen, S.-J., Liao, C.-L., Hsieh, S.-L., Chu, M.-L., Wang, C.-J., Hung, J.-T., *Sytwu, H.-K., *Wang, C.-C. (2006) Kinetic Th1/Th2 responses of transgenic mice with bacterial meningitis induced by Haemophilus influenzae. Clinical Science 111:253-263.
Chen, S.-J., Liao, C.-L., Hsieh, S.-L., Chu, M.-L., Fang, M.-C., *Sytwu, H.-K., *Wang, C.-C. (2006) Kinetics of adaptive immunity to Haemophilus influenzae type b meningitis in transgenic mice: Evidence from diverse expression of double T1/T2 transgenes and Th1/Th2-related cytokines. Immunology Letters 105:6-15.
Hung, J.-T., Liao, J.-H., Lin, Y.-C., Chang, H.-Y., Wu, S.-F., Chang, T.-H., Kung, J., Hsieh, S.-L., McDevitt, H., *Sytwu, H.-K. (2005) Immunopathogenic role of Th1 cells in autoimmune diabetes: Evidence from a T1 and T2 doubly transgenic non-obese diabetic (NOD) model. Journal of Autoimmunity 25:181-192.
Cheng, C.-P., Loh, Y.-X., Lin, C.-I., Lai, Y.-J., Chen, Y.-C., Sytwu, H.-K., Gustafson-Wagner, E.A., and Lin, J.J.-C. (2005) Electrophysiological characteristics of ventricular myocytes of Xina-deficient mice. Advances in Heart Disease 25-29.
Dai, N.-T., Yeh, M.-K., Liu, D., Adams, E.F., Chiang C.-H, Yen, C.-Y., Shih, C.-M., Sytwu, H.-K., Chen, T.-M., Wang, H.-J., Williamson, M.R., Coombes, A.G.A. (2005) A co-cultured skin model based on cell support membranes. Biochemical and Biophysical Research Communications 329:905-908.
Chu, H.-C., Lin, Y.-L., Sytwu, H.-K., Lin, S.-H., Liao, C.-L., and Chao, Y.-C. (2005) Effects of minocycline on Fas-mediated fulminant hepatitis in mice. British Journal of Pharmacology 144:275-282.
Sung, H.-H., Juang, J.-H., Lin, Y.-C., Kuo, C.-H., Hung, J.-T., Chen, A., Chang, D.-M., Chang, S.-Y., Hsieh, S.-L., *Sytwu, H.-K. (2004) Transgenic expression of decoy receptor 3 protects islets from spontaneous and chemical-induced autoimmune destruction in non-obese diabetic mice. Journal of Experimental Medicine 199:1143-1151.
Wang, C.-J., *Sytwu, H.-K. (2004) Application of transgenic and gene knockout mice for the study on immunological diseases. Formosan Journal of Medicine 8:207-213.
Sung, H.-H., Shen, K.-L., and *Sytwu, H.-K. (2004) Immunomodulation by decoy receptor 3: lessons from tumors to therapeutic approaches. Journal of Medical Sciences 24:301-306.
Chang, S.-L., Chang , L.-T., Chiang, Y.-M., Hsieh, R.-H., Tzeng, C.-R., Wu, T.-K., Sytwu, H.-K., Shyur, L.-F., Yang, W.-C. (2004) Polyacetylenic compound and butanol fraction from Bidens pilosa can modulate the differentiation of helper T cells and prevent autoimmune diabetes in non-obese diabetic mice. Planta Medica 70:1045-1051.
Wu, S.-F., Liu, T.-M., Lin, Y.-C., *Sytwu, H.-K., Juan, H.-F., Chen, S.-T., Shen, K.-L., Hsi, S.-C., and Hsieh, S.-L. (2004) Immunomodulatory effect of decoy receptor 3 on the differentiation and function of bone marrow-derived dendritic cells in non-obese diabetic mice: from regulatory mechanism to clinical implication. Journal of Leukocyte Biology 75:293-306.
*Sytwu, H.-K., Lin, W.-D., Roffler, S. R., Hung, J.-T., Sung, H.-H., Wang, C.-H., Cheng, T.-L., Tsou, S.-C., Hsi, S.-C., Shen, K.-L. (2003) Anti-4-1BB-based immunotherapy for autoimmune diabetes: Lessons from a transgenic non-obese diabetic (NOD) model. Journal of Autoimmunity 21:247-254.
Chen, S.-Y., Chen, Y.-C., Wang, J.-K., Hsu, H.-P., Ho, P.-S., Chen, Y.-C., and *Sytwu, H.-K. (2003) Early hyperbaric oxygen therapy attenuates disease severity in lupus-prone autoimmune (NZBXNZW) F1 mice. Clinical Immunology 108:103-110.
Wu, S.-F., Liao, C.-L., Lin, Y.-L., Yeh, C.-T., Chen, L.-K., Huang, Y.-F., Chou, H.-Y., Huang, J.-L., Shaio, M.-F., and *Sytwu, H.-K. (2003) Evaluation of protective efficacy and immune mechanisms of using a nonstructural protein NS1 in DNA vaccine against dengue 2 virus in mice. Vaccine 21:3919-3929.
Lai, H.-J., Sytwu, H.-K., Sun, C.-A., Yu, M.-H., Yu, C.-P., Liu, H.-S., Chang, C.-C., and Chu, T.-Y. (2003) Single nucleotide polymorphism at Fas promoter is associated with cervical carcinogenesis. International Journal of Cancer 103, 221-225.
Tang, I.-K., Ji, D.-D., Chou, C.-F., Lin, H.-C., Liao, C.-L., Sytwu, H.-K. , Wang, J.-J. Liu, Y.-T. (2002). Characterization of a highly attenuated Salmonella enterica serovar Typhimurium mutant strain. J Microbiol Immunol Infect 35: 229-235.
Hsieh, S.-L., Chen, N.-J., Tarbell, K., Liao, N.-S, Lai, Y.-G., Lee, K.-M., Lee, K.-H., Wu, S.-C., Sytwu, H.-K., Han, S.-H., McDevitt, H. (2000). Transgenic mice expressing surface markers for INF-g and IL-4 producing cells. Molecular Immunology 37:281-293.
Liu, D.-W., Tsao, Y.-P., Kung, J.T., Ding, Y.-A., Sytwu, H.-K., Xiao, X., and Chen, S.-L. (2000) Recombinant adeno-associated virus expressing human papillomavirus type 16 E7 peptide DNA fused with heat shock protein DNA as a potential vaccine for cervical cancer. Journal of Virology 74:2888-2894.
Liu, Y.-T., Chen, C.-G., Chao, D.-C., Lee, F., Liao, C.-L., Sytwu, H.-K. , Chou, C.-F., and Ji, D.-D. (1999) Sequence analysis of the Gluconobacter oxydans RecA protein and construction of a recA-deficient mutant. Can J of Microbiol 45: 347-351.
Chao, C.-C., Sytwu, H.-K., Chen, E. L., Toma, J., and McDevitt, H. O. (1999) The role of MHC class II molecules in susceptibility to type I diabetes: Identification of peptide epitopes and characterization of the T cell repertoire. Proc Natl Acad Sci USA 96: 9299-9304.
Singer, S., Tisch, R., Yang, X.-D., Sytwu, H.-K., Liblau, R., and McDevitt, H. O. (1998) Prevention of diabetes in NOD mice by a mutated I-Ab transgene. Diabetes 47:1570-1577.
Michie, A. S., Sytwu, H.-K., McDevitt, H. O., and Yang, X.-D. (1998) The roles of a-4 integrins in the development of insulin-dependent diabetes mellitus. Current topics in microbiology and immunology 231, 65-83.
Yang, X.-D., Sytwu, H.-K., McDevitt, H. O., and Michie, A. S. (1997) Involvement of b7 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in the development of diabetes in nonobese diabetic mice. Diabetes 46, 1542-1547.
Sytwu, H.-K., Liblau, R., and McDevitt, H. O. (1996) The roles of Fas/APO-1 (CD95) and tumor necrosis factor (TNF) in antigen induced programmed cell death in T cell receptor transgenic mice. Immunity, Cell Press, 5, 17-30.
Sytwu, H.-K., Sheu, W.-J., Shih, J.-M., and Chen, S.-L. (1992) Detection and analysis of human papilloma virus type 1 infection of skin warts from a dermatology clinic in Taiwan by Southern hybridization. Chinese J Microbiol Immunol 24:200-214.
Lee, S.-H., Sytwu, H.-K., Liao, C.-L., Lee, J.-H., and Liu, Y.-T. (1989) The β-lactam antibiotic resistance of E. coli isolated from clinic. J. Med. Sci. 10:17-24.
Chapter Book
Yen, B.-L., Liu, K.-J., Yen, M.-L., Sytwu, H.-K. (2016) The modulatory effects of MSCs on the adaptive immune system. The Biology & Therapeutic Applications of Mesenchymal Cells, 490-495, editor Atkinson K, Wiley & Sons, Inc., Hoboken, NJ, USA (http://as.wiley.com/WileyCDA/WileyTitle/productCd-1118907515.html)
21 Nov. 2016
Shyi-Jou, Chen, Hueng-Chuen, Fan, *Huey-Kang, Sytwu. (2012) Immunomodulation of Potent Antioxidant Agents: Preclinical Study to Clinical Application in Multiple Sclerosis. p139-162, Experimental Autoimmune Encephalomyelitis. Edited by Robert Weissert, INTECH BOOK (www.intechopen.com)
Chia-Chao Wu, Kuo-Cheng Lu, Jin-Shuen Chen, Yuh-Feng Lin and *Huey-Kang Sytwu. (2011) Immunopathogenic Mechanism and Therapeutic Intervention in an Experimental Murine Model of Membranous Nephropathy. p87-104, AN UPDATE ON GLOMERULOPATHIES – ETIOLOGY AND PATHOGENESIS. Edited by Sharma S. Prabhakar, INTECH BOOK (www.intechopen.com)
Patent
Yen, B.L., Liu, K.-J., Sytwu, H.-K. (2012) Method for Generating Immunomodulatory Cells, The Cells Prepared Therefrom, and Use Thereof, US 13/607,976 (NHRI TTO case # 1010005)