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Chao-Yuan Hsu Assistant Professor

Chao-Yuan Hsu Assistant Professor      
Chao-Yuan Hsu, Ph.D.

Position

Assistant Professor, Department and Graduate Institute of Microbiology and Immunology, National Defense Medical Center

Education

Ph.D., Graduate Institute of Life Sciences,
National Defense Medical Center, Taipei, Taiwan (2018)
M.S., Department and Graduate Institute of Microbiology and Immunology,
National Defense Medical Center, Taipei, Taiwan (2010)
B.S., Department of Biological Science and Technology,
National Chiao Tung University, Hsinchu, Taiwan (2008)

Professional Experiences

2020-2021: Assistant Professor, Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan

2019-2020: Postdoctoral Research Scholar, National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan

2018-2019: Postdoctoral Fellow, National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan

Research Interests

Gene modulation, Immunotherapy, Autoimmunity, Tumor immunology

My laboratory mainly used the epidemiological analysis data and experimental animal models to explore the asymmetric regulatory role of transcription factors in autoimmune diseases and inflammatory cancer tumors, and establishes a multiple inflammatory immune disease tracking system to evaluate the preventive medical efficacy for immune diseases. We used the gene manipulation technology to analyze the protein expression of transcription factors in T lymphocytes and their post-translational modification from the mouse models for analyzing the key pathogenic mechanisms in inflammatory immune diseases and dissecting the regulatory mechanisms to develop novel immunomodulatory treatment strategies.

Office Phone

+886-2-8792-3100 ext.18536

E-mail

hsucy@mail.ndmctsgh.edu.tw
hsu.chaoyuan@gmail.com

Publications

1. Yi-Wen Tsai, Shin-Huei Fu, Jia-Ling Dong, Ming-Wei Chien, Yu-Wen Liu, Chao-Yuan Hsu* and Huey-Kang Sytwu* (2020). Adipokine-Modulated Immunological Homeostasis Shapes the Pathophysiology of Inflammatory Bowel Disease. International Journal of Molecular Sciences, 21(24): 9564.

2. Chao Yuan Hsu, Shin Huei Fu, Ming Wei Chien, Yu‐Wen Liu, Shyi‐Jou Chen and Huey‐Kang Sytwu* (2020). Post‐Translational Modifications of Transcription Factors Harnessing the Etiology and Pathophysiology in Colonic Diseases. International Journal of Molecular Sciences, 21(9):3207.

3. Shin-Huei Fu, Ming-Wei Chien, Chao-Yuan Hsu, Yu-Wen Liu and Huey-Kang Sytwu* (2020). Interplay between Cytokine Circuitry and Transcriptional Regulation Shaping Helper T Cell Pathogenicity and Plasticity in Inflammatory Bowel Disease. International Journal of Molecular Sciences, 21, 3379.

4. Chao-Yuan Hsu, Li-Tzu Yeh, Shin-Huei Fu, Ming-Wei Chien, Yu-Wen Liu, Shi-Chuen Miaw, Deh-Ming Chang, and Huey-Kang Sytwu* (2018). SUMO-defective c-Maf preferentially transactivates Il21 to exacerbate autoimmune diabetes. The Journal of clinical investigation. 128:3779-3793.

5. Ming-Wei Chien, Shin-Huei Fu, Chao-Yuan Hsu, Yu-Wen Liu and Huey-Kang Sytwu* (2018). The Modulatory Roles of N-glycans in T-Cell-Mediated Autoimmune Diseases. International journal of molecular sciences. 19:780.

6. Ming-Wei Chien, Ming-Hong Lin, Shing-Hwa Huang, Shin-Huei Fu, Chao-Yuan Hsu, B. Lin-Ju Yen, Jiann-Torng Chen, Deh-Ming Chang and Huey-Kang Sytwu* (2015). Glucosamine Modulates T Cell Differentiation through Down-regulating N-Linked Glycosylation of CD25. The Journal of biological chemistry.290:29329-44

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  • Update Date:2023-09-28
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