Professional Experience

Graduate research assistant Dr. James Sutcliffe’s lab 05/1998~10/2000
Dept. of Molecular Physiology and Biophysics
Vanderbilt University
Nashville, TN, U.S.A.

Research assistant/ Dr. Robert Maxson’s lab 11/2000~07/2001
Lab technician II Norris Cancer Center and Hospital
University of Southern California
Los Angeles, CA, U.S.A.

Graduate research assistant Dr. Robert Maxson’s lab 08/2001~ 08/2006
Dept. of Biochemistry and Molecular Biology
University of Southern California
Los Angeles, CA, U.S.A.

Postdoctoral research associate Dr. Robert Maxson’s lab 10/2006~03/2007
Dept. of Biochemistry and Molecular Biology
University of Southern California
Los Angeles, CA, U.S.A.

Postdoctoral research fellow Dr. John Yu’s lab
Stem Cell Program 05/2007~01/2011
Genomics Research Center
Academia Sinica
Taipei, Taiwan

Publication

1. SCI論文：

(1) Lin SC, Gou GH, Hsia CW, Ho CW, Huang KL, Wu YF, Lee SY, and Chen YH*. Simulated microgravity disrupts cytoskeleton organization and increases apoptosis of rat neural crest stem cells via upregulating CXCR4 expression and RhoA-ROCK1-p38 MAPK-p53 signaling. Stem Cells Dev. 2016 Aug 1, 25(15): 1172-1193

(2)Chen CC, Hsia CW, Ho CW, Liang CM, Chen CM, Huang KL, Kang BH, and Chen YH*. Hypoxia and Hyperoxia Differentially Control Proliferation of Rat Neural Crest Stem Cells via Distinct Regulatory Pathways of the HIF1α–CXCR4 and TP53–TPM1 Proteins. Dev. Dyn. 2016 (in press)

(3) Chen, Y.H. and Yu, J. Epigenetic disruptions of histone signatures for the trophectoderm and inner cell mass in mouse parthenogenetic embryos. Stem Cells Dev. 2015 March 1; 24(5):550-564

(4) Lin SC, Gou GH, Hsia CW, Wu YC, Chen YH*. Simulated microgravity increases CXCR4 expression and RhoA signaling, depolymerizes actin and induces neural differentiation of neural crest stem cells from rat hair follicles. Stem Cell Dev. 2014 (in revision)

(5) Chen YH, Yu J. Epigenetic disruptions of histone signatures for the trophectoderm and inner cell mass in mouse parthenogenetic embryos. Stem Cell Dev. 2014 (in press)

(6) Chen YH, Yu J. Ectopic expression of Fgf3 leads to aberrant lineage segregation in the mouse parthenote preimplantation embryos. Dev Dyn. 2012; 241:1651-1664.

(7) Chen YH, Ishii M, Sucov HM, Maxson RE. Msx1 and Msx2 are required for endothelial-mesenchymal transformation of the atrioventricular cushions and patterning of the atrioventricular myocardium. BMC Dev Biol. 2008; 8:75.

(8) Chen YH, Ishii M, Sun J, Sucov HM, Maxson RE. Msx1 and Msx2 regulate survival of secondary heart field precursors and post-migratory proliferation of cardiac neural crest in the outflow tract. Dev Biol. 2007; 308:421-437.


2. 研討會論文：
(1) Simulated microgravity increases CXCR4 expression and RhoA signaling, depolymerizes actin and induces neural differentiation of neural crest stem cells from rat hair follicles. 林幸蓁1、勾國豪2、夏靜吾2、吳怡昌3,4、陳怡潓1#* 1國防醫學院航太及海底醫學研究所, 2國防醫學院醫學科學研究所, 3國防部軍醫局, 4國軍桃園總醫院家庭醫學科。發表於第41屆國軍軍醫學術研討會, 航太與海底醫學組 第三名。

(2) Lin SC, Gou GH, Hsia CW, Wu YC, Chen YH*. Simulated microgravity disrupts cytoskeleton organization and induces differentiation of rat neural crest stem cells via Galpha-mediated CXCR4/ROCK2/p38 signaling. (2014年第十屆台灣幹細胞學會年會)

(3) Chen YH, Yu J. Epigenetic disruptions of histone signatures for the trophectoderm and inner cell mass in mouse parthenogenetic embryos. (2014年台灣發育生物學研討會)

(4) 林幸蓁、陳怡潓*. Microgravity disturbs stress fiber dynamics of cytoskeleton in neural crest stem cells. (第40屆國軍軍醫學術研討會)